Detalhe da pesquisa
1.
N-Acetylglucosamine-1-Phosphate Transferase, WecA, as a Validated Drug Target in Mycobacterium tuberculosis.
Antimicrob Agents Chemother
; 61(11)2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28874370
2.
Optimization of a nucleic acid-based reporter system to detect Mycobacterium tuberculosis antibiotic sensitivity.
Antimicrob Agents Chemother
; 59(1): 407-13, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25367910
3.
Early phase evaluation of SQ109 alone and in combination with rifampicin in pulmonary TB patients.
J Antimicrob Chemother
; 70(5): 1558-66, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25630641
4.
Therapeutic efficacy of SQ641-NE against Mycobacterium tuberculosis.
Antimicrob Agents Chemother
; 58(1): 587-9, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24145521
5.
SQ109 and PNU-100480 interact to kill Mycobacterium tuberculosis in vitro.
J Antimicrob Chemother
; 67(5): 1163-6, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22258923
6.
Chemical modification of capuramycins to enhance antibacterial activity.
J Antimicrob Chemother
; 66(3): 578-87, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21186194
7.
Structure, In Vivo Detection, and Antibacterial Activity of Metabolites of SQ109, an Anti-Infective Drug Candidate.
ACS Infect Dis
; 7(8): 2492-2507, 2021 08 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34279904
8.
In vitro interactions between new antitubercular drug candidates SQ109 and TMC207.
Antimicrob Agents Chemother
; 54(7): 2840-6, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20385864
9.
In vitro antimicrobial activities of capuramycin analogues against non-tuberculous mycobacteria.
J Antimicrob Chemother
; 65(12): 2590-7, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-20952419
10.
Activity of SQ641, a capuramycin analog, in a murine model of tuberculosis.
Antimicrob Agents Chemother
; 53(7): 3138-9, 2009 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19414567
11.
In search of new cures for tuberculosis.
Med Chem
; 3(3): 301-16, 2007 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-17504204
12.
Identification of new diamine scaffolds with activity against Mycobacterium tuberculosis.
J Med Chem
; 49(11): 3045-8, 2006 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16722620
13.
New tuberculosis vaccine development.
Expert Opin Biol Ther
; 2(7): 741-9, 2002 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-12387673
14.
Tuberculosis - drugs in the 2016 development pipeline.
Nat Rev Dis Primers
; 3: 17015, 2017 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28276432
15.
Discovery and development of SQ109: a new antitubercular drug with a novel mechanism of action.
Future Microbiol
; 7(7): 823-37, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22827305
16.
Generation of a novel nucleic acid-based reporter system to detect phenotypic susceptibility to antibiotics in Mycobacterium tuberculosis.
mBio
; 3(2)2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22415006
17.
Anti-tuberculosis drug therapy in mice of different inbred strains.
Infect Genet Evol
; 10(7): 1151-4, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20655396
18.
In vitro antimycobacterial activities of capuramycin analogues.
Antimicrob Agents Chemother
; 52(2): 719-21, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18070956
19.
Preclinical study of new TB drugs and drug combinations in mouse models.
Recent Pat Antiinfect Drug Discov
; 3(2): 102-16, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18673123
20.
Drug therapy of experimental tuberculosis (TB): improved outcome by combining SQ109, a new diamine antibiotic, with existing TB drugs.
Antimicrob Agents Chemother
; 51(4): 1563-5, 2007 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-17242141