Detalhe da pesquisa
1.
PLD3 is a neuronal lysosomal phospholipase D associated with ß-amyloid plaques and cognitive function in Alzheimer's disease.
PLoS Genet
; 17(4): e1009406, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33830999
2.
Autosomal Dominant Alzheimer's Disease Mutations in Human Microglia Are Not Sufficient to Trigger Amyloid Pathology in WT Mice but Might Affect Pathology in 5XFAD Mice.
Int J Mol Sci
; 25(5)2024 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38473822
3.
APOE4 confers transcriptomic and functional alterations to primary mouse microglia.
Neurobiol Dis
; 164: 105615, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35031484
4.
Identifying the molecular systems that influence cognitive resilience to Alzheimer's disease in genetically diverse mice.
Learn Mem
; 27(9): 355-371, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32817302
5.
Genetic architecture of Alzheimer's disease.
Neurobiol Dis
; 143: 104976, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32565066
6.
Translational approaches to understanding resilience to Alzheimer's disease.
Trends Neurosci
; 45(5): 369-383, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35307206
7.
Gene-by-environment modulation of lifespan and weight gain in the murine BXD family.
Nat Metab
; 3(9): 1217-1227, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34552269
8.
Identifying Mechanisms of Normal Cognitive Aging Using a Novel Mouse Genetic Reference Panel.
Front Cell Dev Biol
; 8: 562662, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33042997
9.
Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer's Dementia.
Cell Rep
; 32(9): 108091, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32877673
10.
Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models.
Cell Rep
; 32(2): 107908, 2020 07 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32668255
11.
Knockdown of heterochromatin protein 1 binding protein 3 recapitulates phenotypic, cellular, and molecular features of aging.
Aging Cell
; 18(1): e12886, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30549219
12.
Identification of Pre-symptomatic Gene Signatures That Predict Resilience to Cognitive Decline in the Genetically Diverse AD-BXD Model.
Front Genet
; 10: 35, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30787942
13.
Genetic background modifies CNS-mediated sensorimotor decline in the AD-BXD mouse model of genetic diversity in Alzheimer's disease.
Genes Brain Behav
; 18(8): e12603, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31381246
14.
Harnessing Genetic Complexity to Enhance Translatability of Alzheimer's Disease Mouse Models: A Path toward Precision Medicine.
Neuron
; 101(3): 399-411.e5, 2019 02 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30595332
15.
Identification of a Functional Non-coding Variant in the GABA A Receptor α2 Subunit of the C57BL/6J Mouse Reference Genome: Major Implications for Neuroscience Research.
Front Genet
; 10: 188, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30984232
16.
Cell-Type-Specific Changes in Intrinsic Excitability in the Subiculum following Learning and Exposure to Novel Environmental Contexts.
eNeuro
; 5(6)2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30627661
17.
Hippocampal proteomics defines pathways associated with memory decline and resilience in normal aging and Alzheimer's disease mouse models.
Behav Brain Res
; 322(Pt B): 288-298, 2017 03 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-27265785
18.
Systems genetics identifies Hp1bp3 as a novel modulator of cognitive aging.
Neurobiol Aging
; 46: 58-67, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27460150
19.
TRPC3 channels critically regulate hippocampal excitability and contextual fear memory.
Behav Brain Res
; 281: 69-77, 2015 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25513972
20.
Advances at the intersection of normal brain aging and Alzheimer's disease.
Behav Brain Res
; 322(Pt B): 187-190, 2017 03 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-28231898