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1.
J Strength Cond Res ; 36(3): 832-837, 2022 Mar 01.
Artigo em Inglês | MEDLINE | ID: mdl-35180193

RESUMO

ABSTRACT: Smetanka, RG, Armenta, RF, Nessler, JA, and Newcomer, SC. Heart rate response, duration, grip strength, and anthropometric characteristics in recreational indoor rock climbers. J Strength Cond Res 36(3): 832-837, 2022-Despite the growing popularity of recreational indoor rock climbing, there is a lack of research on cardiovascular responses to rock climbing. In addition, although the importance of body composition and grip strength has been established in elite climbers, their effect on recreational climbing is unknown. Therefore, the purpose of this study was to characterize the physiological and anthropometric characteristics of indoor climbers engaging in climbing at a recreational or noncompetitive setting. We hypothesized that heart rates and climbing durations would meet the standards set by the American College of Sports Medicine (ACSM) and Center for Disease Control and Prevention (CDC) for eliciting health benefits and that grip strength would decrease over the course of a typical climbing session. One hundred twenty-one male and female adult recreational climbers participated in this study. Following informed consent, subjects were instrumented with a heart rate monitor (Polar V800) which recorded heart rate and duration. Preclimb and postclimb grip strength were evaluated using a hand grip dynamometer and used to calculate fatigue. Subjects were 30.9 ± 8.3 years old and had participated in climbing for 5.6 ± 6.5 years. The average heart rate during climbing sessions was 122.3 ± 14.5 b·min-1, and session duration was 90.6 ± 31.3 minutes. Mean grip strength was 49.9 ± 11.2 kg, whereas the strength to mass ratio was 0.71 ± 0.14, and fatigue was 13.1 ± 11.6%. Results from the current study suggest that recreational indoor climbing elicits exercise heart rates and durations that are consistent with the CDC and ACSM's recommendations for cardiovascular health. Grip strength data suggested that forearm muscle fatigue may limit climbing durations.


Assuntos
Montanhismo , Esportes , Adulto , Antropometria , Feminino , Força da Mão/fisiologia , Frequência Cardíaca , Humanos , Masculino , Montanhismo/fisiologia , Resistência Física/fisiologia , Esportes/fisiologia , Adulto Jovem
2.
J Strength Cond Res ; 35(1): 205-211, 2021 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-29912859

RESUMO

ABSTRACT: Crocker, GH, Moon, JF, Nessler, JA, and Newcomer, SC. Energetics of swimming with hand paddles of different surface areas. J Strength Cond Res 35(1): 205-211, 2021-Hand paddles are one of the most common training aids used by the competitive swimmer, yet little is known regarding how hand paddle surface area affects the metabolic cost of transport (COT) while swimming. The purpose of this study was to determine how altering hand paddle size affects energy use during submaximal, front-crawl (i.e., freestyle) swimming. Twenty-six proficient, adult swimmers (13 men and 13 women) completed six 3-minute trials in a flume at a constant pace (102 cm·s-1; 1:38 per 100 m). Trials were performed in random order, using 1 of 5 pairs of hand paddles of different sizes or no paddles at all. Paddle surface areas were 201, 256, 310, 358, and 391 cm2 per hand. Without paddles, COT, arm cadence, and distance per stroke were 7.87 ± 1.32 J·kg-1·m-1, 29.4 ± 4.9 min-1, and 2.13 ± 0.34 m, which corresponded to a rate of oxygen consumption (V̇o2) of 23.3 ± 3.7 ml·kg-1·min-1 and a heart rate (HR) of 118 ± 17 b·min-1. The use of larger hand paddles decreased COT, cadence, V̇o2, and HR and increased distance traveled per stroke (all p < 0.001). However, the magnitude of the change of COT decreased as paddle size increased, indicating diminishing marginal return with increasing paddle surface area. The largest sized paddles increased COT per stroke compared with swimming without paddles (p = 0.001). Therefore, results from this study suggest that an optimal hand paddle size exists (210-358 cm2) for proficient, adult swimmers, which reduces COT without increasing COT per stroke.


Assuntos
Mãos , Natação , Adulto , Fenômenos Biomecânicos , Feminino , Frequência Cardíaca , Humanos , Masculino , Consumo de Oxigênio
3.
J Strength Cond Res ; 35(2): 542-548, 2021 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-29939901

RESUMO

ABSTRACT: Furr, HN, Nessler, JA, and Newcomer, SC. Characterization of heart rate responses, duration, and distances traveled in youth participating in recreational skateboarding at community skateparks. J Strength Cond Res 35(2): 542-548, 2021-Recreational skateboarding continues to gain popularity in youth within the United States and abroad. Surprisingly, there is a paucity of research regarding the cardiovascular responses of youth participating in recreational skateboarding. Therefore, the purpose of this study was to test the hypothesis that skateboarding would elicit heart rates and durations consistent with the American College of Sports Medicine (ACSM) and Center for Disease Control and Prevention (CDC) recommendations for cardiovascular fitness in youth. Seventy-one recreational skateboarders (boys: 63 and girls: 8) between the ages of 6 and 17 years participated in this study. Data were acquired at 9 skateparks in the local community. After parental consent, subjects completed a questionnaire and were instrumented with a heart rate monitor (Polar V800 GPS Sports Watch), which recorded heart rate, duration, and distance traveled. Subjects were instructed to engage in typical skateboarding activities, with the duration and intensity of activity determined by the individual. Subjects were 10.6 ± 2.9 years old and had participated in skateboarding for 3.1 ± 2.4 years. On average, subjects skateboarded 55.5 ± 28.4 minutes, at an average heart rate of 140.4 ± 16.1 b·min-1, and traveled an average distance of 2.65 ± 1.87 km. Results from this study suggest that youth participating in recreational skateboarding at community skateparks attain exercise intensities and durations that are comparable with the ACSM's and CDC's exercise recommendations for cardiovascular fitness in youth. These findings may hold implications for city planners considering the impact of community skateparks on physical activity in youth and overall public health.


Assuntos
Patinação , Medicina Esportiva , Esportes , Adolescente , Criança , Exercício Físico , Feminino , Frequência Cardíaca , Humanos , Masculino , Estados Unidos
4.
J Strength Cond Res ; 33(4): 1102-1110, 2019 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-30741874

RESUMO

Nessler, JA, Ponce-Gonzalez, JG, Robles-Rodriguez, C, Furr, H, Warner, M, and Newcomer, SC. Electromyographic analysis of the surf paddling stroke across multiple intensities. J Strength Cond Res 33(4): 1102-1110, 2019-Surfers spend a majority of their time in the water paddling. The purpose of this study was to examine activity in 5 muscles that contribute to paddling at different velocities and to characterize oxygen use, paddling cadence, and surfboard motion at each velocity. Twelve recreational surfers completed an incremental paddling test on a short surfboard in a swim flume. Surface electromyography was recorded bilaterally from latissimus dorsi, upper and mid trapezius, and posterior and mid deltoid. Electromyographic activity increased as water velocity increased for all muscles, but the change in activation between endurance and sprint paddling was greatest for latissimus dorsi (p < 0.001). At higher water velocities, the middle deltoid was activated earlier in the paddling stroke (p = 0.005). Oxygen use, paddling cadence, and surfboard roll/yaw increased with increasing water velocity. These data may be useful for athletes, trainers, and equipment designers interested in increasing power and efficiency of the paddling stroke.


Assuntos
Músculo Deltoide/fisiologia , Movimento/fisiologia , Esforço Físico/fisiologia , Músculos Superficiais do Dorso/fisiologia , Esportes Aquáticos/fisiologia , Adulto , Eletromiografia , Humanos , Masculino , Consumo de Oxigênio , Adulto Jovem
5.
J Strength Cond Res ; 33(4): 1095-1101, 2019 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-30707140

RESUMO

Furr, HN, Warner, ME, Copeland, TL, Robles-Rodríguez, C, Ponce-González, JG, Nessler, JA, and Newcomer, SC. Differences in V[Combining Dot Above]O2peak of surfers when paddling in water vs. on a swimbench ergometer. J Strength Cond Res 33(4): 1095-1101, 2019-The purpose of this study was to test the hypothesis that surfers would achieve a higher V[Combining Dot Above]O2peak when tested in a swim flume vs. on a swimbench ergometer. Forty-eight surfers (male: 38, female: 10) aged 18-45 years participated in the study. Protocol 1 and 2 both measured heart rate, oxygen consumption (V[Combining Dot Above]O2), and respiratory exchange ratio while subjects performed an incremental paddling test both on a swimbench ergometer and in a swim flume. Protocol 2 additionally measured muscle activity and changes in skin temperature. V[Combining Dot Above]O2peak was significantly higher in the swim flume (33.03 ± 1.04 ml·kg·min) vs. on the swimbench ergometer (29.86 ± 1.08 ml·kg·min) (p value < 0.001). There were also significant differences in muscle activation and changes in skin temperature between the flume and ergometer (p-value < 0.05). Surfers significantly increased their V[Combining Dot Above]O2peak in the water suggesting previous reports of V[Combining Dot Above]O2peak likely underestimated surfer's aerobic fitness when measured on a swimbench ergometer. Future research investigating the aerobic fitness of surfers should be conducted while paddling in water or account for the 11% difference in V[Combining Dot Above]O2peak when tested on a swimbench ergometer.


Assuntos
Teste de Esforço/métodos , Músculo Esquelético/fisiologia , Aptidão Física/fisiologia , Esportes Aquáticos/fisiologia , Adolescente , Adulto , Ergometria , Feminino , Frequência Cardíaca , Humanos , Masculino , Pessoa de Meia-Idade , Consumo de Oxigênio , Troca Gasosa Pulmonar , Temperatura Cutânea , Água , Adulto Jovem
6.
J Strength Cond Res ; 32(2): 372-378, 2018 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-27618226

RESUMO

Furness, J, Hing, W, Sheppard, JM, Newcomer, S, Schram, B, and Climstein, M. Physiological profile of male competitive and recreational surfers. J Strength Cond Res 32(2): 372-378, 2018-Surfing consists of both high- and low-intensity paddling of varying durations, using both the aerobic and anaerobic systems. Surf-specific physiological studies lack adequate group sample sizes, and V[Combining Dot Above]O2peak values are yet to determine the differences between competitive and recreational surfers. The purpose of this study was therefore to provide a comprehensive physiological profile of both recreational and competitive surfers. This multisite study involved 62 male surfers, recreational (n = 47) and competitive (n = 15). Anthropometric measurements were conducted followed by dual-energy x-ray absorptiometry, anaerobic testing and finally aerobic testing. V[Combining Dot Above]O2peak was significantly greater in competitive surfers than in recreational surfers (M = 40.71 ± 3.28 vs. 31.25 ± 6.31 ml·kg·min, p < 0.001). This was also paralleled for anaerobic power (M = 303.93 vs. 264.58 W) for competitive surfers. Arm span and lean total muscle mass was significantly (p ≤ 0.01) correlated with key performance variables (V[Combining Dot Above]O2peak and anaerobic power). No significant (p ≥ 0.05) correlations were revealed between season rank and each of the variables of interest (V[Combining Dot Above]O2peak and anaerobic power). Key performance variables (V[Combining Dot Above]O2peak and anaerobic power) are significantly higher in competitive surfers, indicating that this is both an adaptation and requirement in this cohort. This battery of physiological tests could be used as a screening tool to identify an athlete's weaknesses or strengths. Coaches and clinicians could then select appropriate training regimes to address weaknesses.


Assuntos
Atletas , Desempenho Atlético/fisiologia , Esportes Aquáticos/fisiologia , Absorciometria de Fóton , Adulto , Pesos e Medidas Corporais , Humanos , Masculino , Força Muscular/fisiologia , Músculo Esquelético/fisiologia , Consumo de Oxigênio/fisiologia , Estações do Ano , Adulto Jovem
7.
Ergonomics ; 61(5): 729-735, 2018 May.
Artigo em Inglês | MEDLINE | ID: mdl-28962544

RESUMO

The purpose of this study was to investigate skin temperatures across surfers' bodies while wearing a wetsuit during recreational surfing. Forty-six male recreational surfers participated in this study. Participants were instrumented with eight wireless iButton thermal sensors for the measurement of skin temperature, a Polar RCX5 heart rate monitor and a 2-mm full wetsuit. Following instrumentation, participants were instructed to engage in recreational surfing activities as normal. Significant differences (p < 0.001) in skin temperature (Tsk) were found across the body while wearing a wetsuit during recreational surfing. In addition, regional skin temperature changed across the session for several regions of the body (p < 0.001), and the magnitude of these changes varied significantly between regions. We show for the first time that significant differences exist in skin temperature across the body while wearing a wetsuit during a typical recreational surfing session. These findings may have implications for future wetsuit design. Practitioner Summary: This study investigated the impact of wearing a wetsuit during recreational surfing on regional skin temperatures. Results from this study suggest that skin temperatures differ significantly across the body while wearing a 2-mm wetsuit during recreational surfing. These findings may have implications for future wetsuit design.


Assuntos
Roupa de Proteção , Temperatura Cutânea/fisiologia , Esportes Aquáticos/fisiologia , Adulto , Análise de Variância , Ergonomia , Frequência Cardíaca , Humanos , Masculino , Inquéritos e Questionários , Adulto Jovem
8.
J Aging Phys Act ; 25(2): 182-188, 2017 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-27623020

RESUMO

Participation in surfing has evolved to include all age groups. Therefore, the purpose of this study was to determine whether activity levels and cardiovascular responses to surfing change with age. Surfing time and heart rate (HR) were measured for the total surfing session and within each activity of surfing (paddling, sitting, wave riding, and miscellaneous). Peak oxygen consumption (VO2peak) was also measured during laboratory-based simulated surfboard paddling on a modified swim bench ergometer. VO2peak decreased with age during simulated paddling (r = -.455, p < .001, n = 68). Total time surfing (p = .837) and time spent within each activity of surfing did not differ with age (n = 160). Mean HR during surfing significantly decreased with age (r = -.231, p = .004). However, surfing HR expressed as a percent of age-predicted maximum increased significantly with age. Therefore, recreational surfers across the age spectrum are achieving intensities and durations that are consistent with guidelines for cardiovascular health.


Assuntos
Desempenho Atlético/fisiologia , Frequência Cardíaca/fisiologia , Consumo de Oxigênio/fisiologia , Natação/fisiologia , Adolescente , Adulto , Fatores Etários , Idoso , California , Humanos , Masculino , Pessoa de Meia-Idade
9.
Ergonomics ; 60(9): 1255-1260, 2017 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-27875943

RESUMO

The purpose of this study was to investigate how altering surfboard volume (BV) affects energy expenditure during paddling. Twenty surfers paddled in a swim flume on five surfboards in random order twice. All surfboards varied only in thickness and ranged in BV from 28.4 to 37.4 L. Measurements of heart rate (HR), oxygen consumption (VO2), pitch angle, roll angle and paddling cadence were measured. VO2 and HR significantly decreased on thicker boards [VO2: r = -0.984, p = 0.003; HR: r = -0.972, p = 0.006]. There was also a significant decrease in pitch and roll angles on thicker boards [Pitch: r = -0.995, p < 0.001; Roll: r = -0.911, p = 0.031]. Results from this study suggest that increasing BV reduces the metabolic cost of paddling as a result of lower pitch and roll angles, thus providing mechanical evidence for increased paddling efficiency on surfboards with more volume. Practioner Summary: This study investigated the impact of surfboard volume on energy expenditure during paddling. Results from this study suggest that increasing surfboard volume reduces the metabolic cost of paddling as a result of lower pitch and roll angles, thus providing mechanical evidence for increased paddling efficiency on surfboards with more volume.


Assuntos
Metabolismo Energético , Desenho de Equipamento , Equipamentos Esportivos/estatística & dados numéricos , Esportes Aquáticos/fisiologia , Adulto , Feminino , Frequência Cardíaca/fisiologia , Humanos , Masculino , Consumo de Oxigênio/fisiologia , Método Simples-Cego
10.
J Appl Biomech ; 33(4): 282-287, 2017 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-28253044

RESUMO

Low back pain is a commonly reported problem among recreational surfers. Some individuals report that wearing a vest with an inflatable bladder that alters trunk angle may help to alleviate pain. The purpose of this study was to determine whether such a vest has an effect on muscle activation and extension of the lower back. Twelve recreational surfers completed 12 paddling trials at 1.1 m/s in a swim flume on both a shortboard and a longboard on 2 separate days. Three conditions of no vest, vest uninflated, and vest inflated were presented to participants in random order. Surface EMG and trunk angle were acquired via wireless sensors placed over the right erector spinae, mid-trapezius, upper trapezius, and latissimus dorsi. Wearing the inflated vest affected muscle activation: erector spinae and mid-trapezius demonstrated a significant decrease in activation relative to wearing no vest (12% and 18% respectively, p < .05). Trunk extension was also significantly reduced when the vest was inflated (18% reduction, p < .05). Results were similar for both the short and longboard, though this effect was greater while paddling the larger board. These results suggest that a properly inflated vest can alter trunk extension and muscle activity while paddling a surfboard in water.


Assuntos
Vestuário , Dor Lombar/prevenção & controle , Dor Lombar/fisiopatologia , Fenômenos Fisiológicos Musculoesqueléticos , Esportes/fisiologia , Tronco/fisiologia , Adulto , Eletromiografia , Voluntários Saudáveis , Humanos , Masculino
11.
J Hepatol ; 64(1): 171-8, 2016 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-26325536

RESUMO

BACKGROUND & AIMS: Mounting evidence indicates that maternal exercise confers protection to adult offspring against various diseases. Here we hypothesized that maternal exercise during gestation would reduce high-fat diet (HFD)-induced hepatic steatosis in adult rat offspring. METHODS: Following conception, pregnant dams were divided into either voluntary wheel running exercise (GE) or wheel-locked sedentary (GS) groups throughout gestation (days 4-21). Post-weaning, offspring received either normal chow diet (CD; 10% fat, 70% carbohydrate, 20% protein) or HFD (45% fat, 35% carbohydrate, and 20% protein) until sacrificed at 4- or 8-months of age. RESULTS: GE did not affect offspring birth weight or litter size. HFD feeding in offspring increased weight gain, body fat percentage, and glucose tolerance test area under the curve (GTT-AUC). Male offspring from GE dams had reduced body fat percentage across all ages (p<0.05). In addition, 8-month male offspring from GE dams were protected against HFD-induced hepatic steatosis, which was associated with increased markers of hepatic mitochondrial biogenesis (PGC-1α and TFAM), autophagic potential (ATG12:ATG5 conjugation) and hepatic triacylglycerol secretion (MTTP). CONCLUSIONS: The current study provides the first evidence that gestational exercise can reduce susceptibility to HFD-induced hepatic steatosis in adult male offspring.


Assuntos
Hepatopatia Gordurosa não Alcoólica/prevenção & controle , Condicionamento Físico Animal , Animais , Proteínas de Transporte/análise , Dieta Hiperlipídica , Feminino , Masculino , Coativador 1-alfa do Receptor gama Ativado por Proliferador de Peroxissomo , Gravidez , Ratos , Ratos Sprague-Dawley , Fatores de Transcrição/análise
12.
J Strength Cond Res ; 30(6): 1721-6, 2016 06.
Artigo em Inglês | MEDLINE | ID: mdl-26562714

RESUMO

Despite the nation's rising epidemic of childhood obesity and diabetes, schools struggle to promote physical activities that help reduce risks for cardiovascular disease. Emerging data suggest that adopting novel activities into physical education (PE) curriculum may serve as an effective strategy for increasing physical activity in children. The purpose of this investigation was to characterize activity in the water and heart rates (HRs) of high school students participating in surf PE courses. Twenty-four male (n = 20) and female (n = 4) high school students (mean age = 16.7 ± 1.0 years) who were enrolled in surf PE courses at 2 high schools participated in this investigation. Daily measurements of surfing durations, average HR, and maximum HR were made on the students with HR monitors (PolarFT1) over an 8-week period. In addition, HR and activity in the water was evaluated during a single session in a subset of students (n = 11) using a HR monitor (PolarRCX5) and a video camera (Canon HD). Activity and HR were synchronized and evaluated in 5-second intervals during data analyses. The average duration that PE students participated in surfing during class was 61.7 ± 1.0 minutes. Stationary, paddling, wave riding, and miscellaneous activities comprised 42.7 ± 9.5, 36.7 ± 7.9, 2.9 ± 1.4, and 17.8 ± 11.4 percent of the surf session, respectively. The average and maximum HRs during these activities were 131.1 ± 0.9 and 177.2 ± 1.0 b·min, respectively. These data suggest that high school students participating in surf PE attained HRs and durations that are consistent with recommendations with cardiovascular fitness and health. In the future, PE programs should consider incorporating other action sports into their curriculum to enhance cardiovascular health.


Assuntos
Frequência Cardíaca/fisiologia , Força Muscular/fisiologia , Músculo Esquelético/patologia , Treinamento Resistido/métodos , Natação/fisiologia , Adolescente , Exercício Físico , Feminino , Humanos , Hipertrofia , Masculino
13.
Exerc Sport Sci Rev ; 43(4): 198-203, 2015 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-26196867

RESUMO

Maternal behaviors during pregnancy have been reported to impact offspring health in adulthood. In this article we explore the novel hypothesis that exercise during pregnancy can protect against chronic disease susceptibility in the offspring. To date, research has demonstrated that improvements in metabolic outcomes, cardiovascular risk, and cancer can occur in response to maternal exercise during pregnancy.


Assuntos
Doença Crônica/prevenção & controle , Suscetibilidade a Doenças , Exercício Físico , Gravidez , Doenças Cardiovasculares/prevenção & controle , Feminino , Humanos , Doenças Metabólicas/prevenção & controle , Neoplasias/prevenção & controle , Fatores de Risco
14.
Exp Physiol ; 99(1): 205-19, 2014 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-24163423

RESUMO

The intrauterine environment is influenced by maternal behaviour and programmes atherosclerotic disease susceptibility in offspring. The aim of this investigation was to test the hypothesis that mothers' exercise during pregnancy improves endothelial function in 3-, 5- and 9-month-old porcine offspring. The pregnant sows in the exercise group ran for an average of 39.35 ± 0.75 min at 4.81 ± 0.35 km h(-1) each day for 5 days per week for all but the last week of gestation. This induced a significant reduction in resting heart rate (exercised group, 89.3 ± 3.5 beats min(-1); sedentary group, 102.1 ± 3.1 beats min(-1); P < 0.05) but no significant differences in gestational weight gain (65.8 ± 2.1 versus 63.3 ± 1.9%). No significant effect on bradykinin-induced vasorelaxation with and without l-NAME was observed. A significant main effect was identified on sodium nitroprusside-induced vasorelaxation (P = 0.01), manifested by a reduced response in femoral arteries of all age groups from exercised-trained swine. Nitric oxide signalling was not affected by maternal exercise. Protein expression of MYPT1 was reduced in femoral arteries from 3-month-old offspring of exercised animals. A significant interaction was observed for PPP1R14A (P < 0.05) transcript abundance and its protein product CPI-17. In conclusion, pregnant swine are able to complete an exercise-training protocol that matches the current recommendations for pregnant women. Gestational exercise is a potent stimulus for programming vascular smooth muscle relaxation in adult offspring. Specifically, exercise training for the finite duration of pregnancy decreases vascular smooth muscle responsiveness in adult offspring to an exogenous nitric oxide donor.


Assuntos
Músculo Liso Vascular/fisiologia , Condicionamento Físico Animal/fisiologia , Sistema Vasomotor/fisiologia , Animais , Endotélio Vascular/metabolismo , Endotélio Vascular/fisiologia , Feminino , Artéria Femoral/metabolismo , Artéria Femoral/fisiologia , Frequência Cardíaca/fisiologia , Mães , Relaxamento Muscular/fisiologia , Músculo Liso Vascular/metabolismo , Fosfatase de Miosina-de-Cadeia-Leve/metabolismo , Óxido Nítrico/metabolismo , Doadores de Óxido Nítrico/metabolismo , Gravidez , Suínos , Vasodilatação/fisiologia , Sistema Vasomotor/metabolismo
15.
BMC Pregnancy Childbirth ; 14: 405, 2014 Dec 12.
Artigo em Inglês | MEDLINE | ID: mdl-25495072

RESUMO

BACKGROUND: The development of long-term vascular disease can be linked to the intrauterine environment, and maternal nutrition during gestation plays a critical role in the future vascular health of offspring. The purpose of this investigation was to test the hypothesis that a high-energy (HE) gestational diet, HE post-weaning diet, or their combination will lead to endothelial dysfunction in offspring. METHODS: Duroc × Landrace gilts (n = 16) were assigned to either a HE (10,144 Kcal/day, n = 8) or normal energy (NE: 6721 Kcal/day, n = 8) diet throughout pregnancy. Piglets were placed on either a NE or HE diet during the growth phase. At 3 months of age femoral arteries were harvested from offspring (n = 47). Endothelial-dependent and -independent vasorelaxation was measured utilizing wire-myography and increasing concentrations of bradykinin (BK) and sodium nitroprusside (SNP), respectively. RESULTS: BK and SNP induced vasorelaxation were significantly reduced in the femoral arteries of gestational HE offspring. However, no effect for the post-weaning diet on BK and SNP induced vasorelaxation was seen. This investigation demonstrates that a HE diet prenatally diminishes both BK and SNP induced vasorelaxation in swine. CONCLUSIONS: These findings suggest that a HE gestational diet can play a critical role in the development of offspring's vascular function, predisposing them to endothelial dysfunction. This dysfunction may lead to atherosclerotic disease development later in life.


Assuntos
Dieta Hiperlipídica , Ingestão de Energia , Prenhez , Doenças Vasculares/etiologia , Animais , Animais Recém-Nascidos , Aterosclerose/etiologia , Aterosclerose/prevenção & controle , Biomarcadores/metabolismo , Vasos Sanguíneos/fisiopatologia , Bradicinina/análise , Bradicinina/metabolismo , Endotélio Vascular/patologia , Endotélio Vascular/fisiopatologia , Comportamento Alimentar , Feminino , Idade Gestacional , Nitroprussiato/análise , Nitroprussiato/metabolismo , Cuidado Pós-Natal/métodos , Gravidez , Distribuição Aleatória , Valores de Referência , Medição de Risco , Suínos , Doenças Vasculares/diagnóstico , Vasodilatação/fisiologia , Desmame
16.
BMC Genomics ; 14: 443, 2013 Jul 03.
Artigo em Inglês | MEDLINE | ID: mdl-23822099

RESUMO

BACKGROUND: The heterogeneous progression of atherosclerotic disease in the peripheral arteries is currently not well understood. In humans, artery specific disease progression is partly attributed to the local hemodynamic environments. However, despite similar hemodynamic environments, porcine brachial arteries are protected while femoral arteries are highly susceptible to advanced lesion formation. The aim of this investigation was to determine whether artery specific gene expression patterns contribute to the uneven distribution of peripheral arterial disease (PAD) in Rapacz Familial-Hypercholesterolemic (FHC) swine. RESULTS: Histological results confirmed rapid atherosclerotic disease progression in femoral but not brachial arteries. A total of 18,922 probe sets had sufficient signal abundance. A main effect for age and artery was observed for 1784 and 1256 probe sets, respectively. A significant age x artery interaction was found for 184 probe sets. Furthermore, comparison between arteries found a decrease from 714 to 370 differentially expressed transcripts from nine months to two years of age. Gene ontology analysis of the 56 genes with a main effect for artery and an age x artery interaction identified vascular smooth muscle contraction as enhanced biological signaling pathway. CONCLUSION: This is the first investigation to report that the total number of differential genes decreases with diverging atherosclerotic disease pattern between porcine brachial and femoral arteries.


Assuntos
Aterosclerose/complicações , Aterosclerose/genética , Progressão da Doença , Hiperlipoproteinemia Tipo II/complicações , Doença Arterial Periférica/complicações , Doença Arterial Periférica/genética , Transcriptoma , Animais , Aterosclerose/patologia , Doença Arterial Periférica/patologia , Suínos
17.
J Vasc Surg ; 58(6): 1688-96, 2013 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-24280329

RESUMO

The capability for externally applied rhythmic limb compressions to improve the outcomes of patients with peripheral artery disease has been recognized for nearly a century. Modern technology has permitted the development of portable and cost-effective intermittent pneumatic compression (IPC) systems to be made readily available for affordable at-home use. Mounting clinical evidence attests to the effectiveness of this strategy, with improvements in claudication distance rivaling those seen with exercise training or pharmacologic interventions, or both. However, owing to a lack of mechanistic knowledge, whether current application protocols are optimized for clinical outcomes is unknown. Traditional thinking has suggested that IPC transiently elevates blood flow, which is purported to relieve ischemia, improve vascular function, and promote vascular remodeling. Surprisingly, much ambiguity exists regarding the physiologic stimuli and adaptations that are responsible for the clinical effectiveness of IPC treatment. This review presents and critically discusses emerging evidence that sheds new light on the physiologic and molecular responses to IPC therapy. These novel findings highlight the importance of characterizing the phasic changes in the hemodynamic profile during IPC application. Further, these studies indicate that factors other than the elevation in blood flow during this therapy should be taken into account when designing an optimal IPC device. Lastly, we advance the hypothesis that manipulation of IPC stimulation characteristics could potentially magnify the documented clinical benefits associated with this therapy. In conclusion, recent evidence challenges the physiologic basis on which current IPC systems were designed, and further research to elucidate the basic and clinical outcomes of alternate stimulation characteristics is necessary.


Assuntos
Dispositivos de Compressão Pneumática Intermitente , Perna (Membro)/irrigação sanguínea , Doença Arterial Periférica/terapia , Humanos , Doença Arterial Periférica/fisiopatologia , Fluxo Sanguíneo Regional/fisiologia , Resultado do Tratamento
18.
J Spinal Cord Med ; 36(2): 104-11, 2013 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-23809524

RESUMO

OBJECTIVE: To investigate lower-extremity arterial hemodynamics in individuals with spinal cord injury (SCI). We hypothesized that oscillatory shear index would be altered and resting mean shear would be higher in the lower-extremity arteries of SCI. RESEARCH: Cross-sectional study of men and women with SCIs compared to able-bodied controls. SUBJECTS: Subjects included 105 ages 18-72 years with American Spinal Injury Association (ASIA) Impairment Scale grades A, B, or C and injury duration at least 5 years. Subjects were matched for age and cardiovascular disease risk factors with 156 able-bodied controls. METHODS: Diameter and blood velocity were determined with subject at rest via ultrasound in superficial femoral, popliteal, brachial, and carotid arteries. Mean shear, antegrade shear, retrograde shear, and oscillatory shear index were calculated. RESULTS: Oscillatory shear index was lower in SCI compared to controls for superficial femoral (0.16 ± 0.10 vs. 0.26 ± 0.06, P < 0.01) and popliteal arteries (0.20 ± 0.11 vs. 0.26 ± 0.05, P < 0.01). Mean shear rate was higher in SCI compared to controls for superficial femoral (43.54 ± 28.0 vs. 20.48 ± 13.1/second, P < 0.01) and popliteal arteries (30.43 ± 28.1 vs. 11.68 ± 9.5/second, P < 0.01). CONCLUSIONS: The altered resting hemodynamics in SCI are consistent with an atheroprotective hemodynamic environment.


Assuntos
Hemodinâmica/fisiologia , Extremidade Inferior/irrigação sanguínea , Traumatismos da Medula Espinal/diagnóstico por imagem , Traumatismos da Medula Espinal/fisiopatologia , Adolescente , Adulto , Idoso , Estudos Transversais , Feminino , Artéria Femoral/diagnóstico por imagem , Humanos , Extremidade Inferior/diagnóstico por imagem , Masculino , Pessoa de Meia-Idade , Artéria Poplítea/diagnóstico por imagem , Ultrassonografia
19.
Int J Exerc Sci ; 16(7): 599-612, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37621876

RESUMO

Prior research has demonstrated that male adults and youth engaged in skateboarding at community skateparks achieve heart rates that meet or exceed recommendations for exercise by the CDC. However, these studies do not adequately evaluate other non-traditional or ethnically diverse users who may differ in how they utilize the skatepark and in their cardiovascular response. The purpose of this experiment was to measure heart rate response and locomotor movement in three lesser studied groups that frequently utilize community skateparks, and to compare these results with those reported previously in male adult and youth skateboarders. Fifty-six skatepark users were analyzed, including thirty female and BIPOC skateboarders, and twenty-six non-skateboard users. All participants were instrumented with a HR monitor with GPS capability and asked to engage in their preferred activity with no duration specified. Average heart rate and time spent at high and moderate levels of heart rate intensity were not statistically different among the groups studied here, nor were they different from those reported previously for male adult and youth skateboarders. Distances traveled, average, and peak velocities were also not statistically different among the groups studied here, but all were significantly lower than values previously reported for adult male skateboarders. While some differences in distances traveled and velocity were noted, all groups met or exceeded CDC guidelines for cardiovascular fitness. These data suggest that skateparks can help a community achieve health outcomes, particularly among diverse users.

20.
Appl Ergon ; 113: 104108, 2023 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-37572425

RESUMO

The purpose of this study was to characterize the perception of heat loss, comfort, and wetness in recreational surfers wearing wetsuits, to compare these data with changes in skin temperature reported in prior studies, and to examine the impact of wetsuit thickness, zipper location, and accessory use on thermal sensation and comfort. Following their surf session, nine-hundred and three male (n = 735) and female (n = 168) recreational surfers responded to a series of questions regarding thermal comfort/sensation, wetsuit characteristics, and surfing history. Average whole body thermal sensation rating was 0.8 ± 3.6 on a scale of -10 to +10 and average whole body thermal comfort rating was 1.5 ± 1.2, midway between "just comfortable" and "comfortable." Overall, surfers felt coldest in their feet, hands, and head. Under their wetsuits, surfers felt the coldest, wettest, and least comfortable in their chest, lower legs, lower arms, and upper back. Wetsuit accessory use had the greatest impact on regions identified as coldest, least comfortable, and wettest. These data suggest that wetsuit design should focus on optimizing water access points and improving accessories for the feet, hands, and head.


Assuntos
Esportes , Humanos , Masculino , Feminino , Temperatura Cutânea , Temperatura Baixa , Regulação da Temperatura Corporal , Percepção
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