Detalhe da pesquisa
1.
The Myxobacterial Antibiotic Myxovalargin: Biosynthesis, Structural Revision, Total Synthesis, and Molecular Characterization of Ribosomal Inhibition.
J Am Chem Soc
; 145(2): 851-863, 2023 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36603206
2.
Bifunctional Nitrone-Conjugated Secondary Metabolite Targeting the Ribosome.
J Am Chem Soc
; 142(43): 18369-18377, 2020 10 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32709196
3.
Structures of the orthosomycin antibiotics avilamycin and evernimicin in complex with the bacterial 70S ribosome.
Proc Natl Acad Sci U S A
; 113(27): 7527-32, 2016 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27330110
4.
Structure of the mammalian antimicrobial peptide Bac7(1-16) bound within the exit tunnel of a bacterial ribosome.
Nucleic Acids Res
; 44(5): 2429-38, 2016 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26792896
5.
Cryo-EM structure of the tetracycline resistance protein TetM in complex with a translating ribosome at 3.9-Å resolution.
Proc Natl Acad Sci U S A
; 112(17): 5401-6, 2015 Apr 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-25870267
6.
Total Synthesis and Structural Revision of the Antibiotic Tetrapeptide GE81112A.
Angew Chem Int Ed Engl
; 57(37): 12157-12161, 2018 09 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30004165
7.
Proline-rich antimicrobial peptides targeting protein synthesis.
Nat Prod Rep
; 34(7): 702-711, 2017 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28537612
8.
Tetracycline antibiotics and resistance mechanisms.
Biol Chem
; 395(5): 559-75, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24497223
9.
Full Profiling of GE81112A, an Underexplored Tetrapeptide Antibiotic with Activity against Gram-Negative Pathogens.
Microbiol Spectr
; 11(3): e0224722, 2023 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37140391
10.
The proline-rich antimicrobial peptide Onc112 inhibits translation by blocking and destabilizing the initiation complex.
Nat Struct Mol Biol
; 22(6): 470-5, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25984971
11.
Amythiamicinâ D and related thiopeptides as inhibitors of the bacterial elongation factor EF-Tu: modification of the amino acid at carbon atom C2 of ringâ C dramatically influences activity.
ChemMedChem
; 8(12): 1954-62, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24106106