Detalhe da pesquisa
1.
Inhibiting Inflammation with Myeloid Cell-Specific Nanobiologics Promotes Organ Transplant Acceptance.
Immunity
; 49(5): 819-828.e6, 2018 11 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30413362
2.
Externalized histone H4 orchestrates chronic inflammation by inducing lytic cell death.
Nature
; 569(7755): 236-240, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31043745
3.
M6229 Protects against Extracellular-Histone-Induced Liver Injury, Kidney Dysfunction, and Mortality in a Rat Model of Acute Hyperinflammation.
Int J Mol Sci
; 25(3)2024 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38338654
4.
The role of extracellular histones in COVID-19.
J Intern Med
; 293(3): 275-292, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36382685
5.
N-glycan-mediated shielding of ADAMTS13 prevents binding of pathogenic autoantibodies in immune-mediated TTP.
Blood
; 137(19): 2694-2698, 2021 05 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33544829
6.
Inhibition of Neutral Sphingomyelinase 2 by Novel Small Molecule Inhibitors Results in Decreased Release of Extracellular Vesicles by Vascular Smooth Muscle Cells and Attenuated Calcification.
Int J Mol Sci
; 24(3)2023 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36768348
7.
Conformational plasticity of ADAMTS13 in hemostasis and autoimmunity.
J Biol Chem
; 297(4): 101132, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34461090
8.
Endotoxinemia Accelerates Atherosclerosis Through Electrostatic Charge-Mediated Monocyte Adhesion.
Circulation
; 143(3): 254-266, 2021 01 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33167684
9.
ptFVa (Pseudonaja Textilis Venom-Derived Factor Va) Retains Structural Integrity Following Proteolysis by Activated Protein C.
Arterioscler Thromb Vasc Biol
; 41(8): 2263-2276, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34162230
10.
Structure-Based Cyclic Glycoprotein Ibα-Derived Peptides Interfering with von Willebrand Factor-Binding, Affecting Platelet Aggregation under Shear.
Int J Mol Sci
; 23(4)2022 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35216161
11.
Modifying ADAMTS13 to modulate binding of pathogenic autoantibodies of patients with acquired thrombotic thrombocytopenic purpura.
Haematologica
; 105(11): 2619-2630, 2020 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33131251
12.
Deficiency of the T cell regulator Casitas B-cell lymphoma-B aggravates atherosclerosis by inducing CD8+ T cell-mediated macrophage death.
Eur Heart J
; 40(4): 372-382, 2019 01 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30452556
13.
Child-onset thrombotic thrombocytopenic purpura caused by p.R498C and p.G259PfsX133 mutations in ADAMTS13.
Eur J Haematol
; 2018 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29763513
14.
iPPI-DB: an online database of modulators of protein-protein interactions.
Nucleic Acids Res
; 44(D1): D542-7, 2016 Jan 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26432833
15.
Inhibition of CD40-TRAF6 interactions by the small molecule inhibitor 6877002 reduces neuroinflammation.
J Neuroinflammation
; 14(1): 105, 2017 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28494768
16.
Neutrophils and Contact Activation of Coagulation as Potential Drivers of COVID-19.
Circulation
; 142(18): 1787-1790, 2020 11 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32946302
17.
Rational design of small molecules targeting the C2 domain of coagulation factor VIII.
Blood
; 123(1): 113-20, 2014 Jan 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-24227818
18.
Nonanticoagulant heparin prevents histone-mediated cytotoxicity in vitro and improves survival in sepsis.
Blood
; 123(7): 1098-101, 2014 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24264231
19.
Discovery of small molecule CD40-TRAF6 inhibitors.
J Chem Inf Model
; 55(2): 294-307, 2015 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25622654
20.
Factor Xa activation of factor V is of paramount importance in initiating the coagulation system: lessons from a tick salivary protein.
Circulation
; 128(3): 254-66, 2013 Jul 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-23817575