Detalhe da pesquisa
1.
Metallohelix vectors for efficient gene delivery via cationic DNA nanoparticles.
Nucleic Acids Res
; 50(2): 674-683, 2022 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35018455
2.
Cyclometalated Benzimidazole Osmium(II) Complexes with Antiproliferative Activity in Cancer Cells Disrupt Calcium Homeostasis.
Inorg Chem
; 62(16): 6474-6487, 2023 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37040203
3.
Multitargeting Prodrugs that Release Oxaliplatin, Doxorubicin and Gemcitabine are Potent Inhibitors of Tumor Growth and Effective Inducers of Immunogenic Cell Death.
Angew Chem Int Ed Engl
; 62(42): e202310774, 2023 10 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37646232
4.
A Cyclometalated IrIII Complex Conjugated to a Coumarin Derivative Is a Potent Photodynamic Agent against Prostate Differentiated and Tumorigenic Cancer Stem Cells.
Chemistry
; 27(33): 8547-8556, 2021 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33835526
5.
Optically Pure Metallohelices That Accumulate in Cell Nuclei, Condense/Aggregate DNA, and Inhibit Activities of DNA Processing Enzymes.
Inorg Chem
; 59(5): 3304-3311, 2020 Mar 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32064865
6.
Platinum (IV) Derivatives with Cinnamate Axial Ligands as Potent Agents Against Both Differentiated and Tumorigenic Cancer Stem Rhabdomyosarcoma Cells.
Angew Chem Int Ed Engl
; 59(8): 3329-3335, 2020 02 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31802607
7.
Glycoconjugated Metallohelices have Improved Nuclear Delivery and Suppress Tumour Growth In Vivo.
Angew Chem Int Ed Engl
; 59(34): 14677-14685, 2020 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32489012
8.
Towards Novel Photodynamic Anticancer Agents Generating Superoxide Anion Radicals: A Cyclometalated IrIII Complex Conjugated to a Far-Red Emitting Coumarin.
Angew Chem Int Ed Engl
; 58(19): 6311-6315, 2019 05 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30889300
9.
Exploring the Effect of Polypyridyl Ligands on the Anticancer Activity of Phosphorescent Iridium(III) Complexes: From Proteosynthesis Inhibitors to Photodynamic Therapy Agents.
Chemistry
; 24(18): 4607-4619, 2018 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29369444
10.
Organoruthenium Complexes with C
Chemistry
; 23(61): 15294-15299, 2017 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28922506
11.
Novel Antitumor Platinum(II) Conjugates Containing the Nonsteroidal Anti-inflammatory Agent Diclofenac: Synthesis and Dual Mechanisms of Antiproliferative Effects.
Inorg Chem
; 56(3): 1483-1497, 2017 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28102676
12.
Internalization of Ineffective Platinum Complex in Nanocapsules Renders It Cytotoxic.
Chemistry
; 22(8): 2728-35, 2016 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26789279
13.
Enhancing Tumor Cell Response to Chemotherapy through the Targeted Delivery of Platinum Drugs Mediated by Highly Stable, Multifunctional Carboxymethylcellulose-Coated Magnetic Nanoparticles.
Chemistry
; 22(28): 9750-9, 2016 Jul 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27246144
14.
Photoactivatable, mitochondria targeting dppz iridium(III) complex selectively interacts and damages mitochondrial DNA in cancer cells.
Chem Biol Interact
; 392: 110921, 2024 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38382705
15.
Multiaction Pt(IV) Prodrugs Releasing Cisplatin and Dasatinib Are Potent Anticancer and Anti-Invasive Agents Displaying Synergism between the Two Drugs.
J Med Chem
; 67(11): 9745-9758, 2024 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38819023
16.
Novel 2-(5-Arylthiophen-2-yl)-benzoazole Cyclometalated Iridium(III) dppz Complexes Exhibit Selective Phototoxicity in Cancer Cells by Lysosomal Damage and Oncosis.
J Med Chem
; 67(1): 691-708, 2024 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38141031
17.
Energetics, conformation, and recognition of DNA duplexes containing a major adduct of an anticancer azolato-bridged dinuclear Pt(II) complex.
Biochim Biophys Acta
; 1820(10): 1502-11, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22683702
18.
Ir(III) Compounds Containing a Terdentate Ligand Are Potent Inhibitors of Proliferation and Effective Antimetastatic Agents in Aggressive Triple-Negative Breast Cancer Cells.
J Med Chem
; 66(14): 9766-9783, 2023 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37410386
19.
N-Indolyl diiron vinyliminium complexes exhibit antiproliferative effects in cancer cells associated with disruption of mitochondrial homeostasis, ROS scavenging, and antioxidant activity.
Chem Biol Interact
; 385: 110742, 2023 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37802407
20.
Dipyridophenazine iridium(III) complex as a phototoxic cancer stem cell selective, mitochondria targeting agent.
Chem Biol Interact
; 360: 109955, 2022 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35447138