Detalhe da pesquisa
1.
Aberrant stromal tissue factor localisation and mycolactone-driven vascular dysfunction, exacerbated by IL-1ß, are linked to fibrin formation in Buruli ulcer lesions.
PLoS Pathog
; 18(1): e1010280, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35100311
2.
Pharmacological modulation of T cell immunity results in long-term remission of autoimmune arthritis.
Proc Natl Acad Sci U S A
; 118(19)2021 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33941676
3.
LAT1 enables T cell activation under inflammatory conditions.
J Autoimmun
; 138: 103031, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37229811
4.
Mycolactone enhances the Ca2+ leak from endoplasmic reticulum by trapping Sec61 translocons in a Ca2+ permeable state.
Biochem J
; 478(22): 4005-4024, 2021 11 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34726690
5.
TNF receptor 2 signaling prevents DNA methylation at the Foxp3 promoter and prevents pathogenic conversion of regulatory T cells.
Proc Natl Acad Sci U S A
; 116(43): 21666-21672, 2019 10 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-31597740
6.
Mycolactone-Dependent Depletion of Endothelial Cell Thrombomodulin Is Strongly Associated with Fibrin Deposition in Buruli Ulcer Lesions.
PLoS Pathog
; 11(7): e1005011, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26181660
7.
The pathogenic mechanism of the Mycobacterium ulcerans virulence factor, mycolactone, depends on blockade of protein translocation into the ER.
PLoS Pathog
; 10(4): e1004061, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24699819
8.
Induction of IDO1 and Kynurenine by Serine Proteases Subtilisin, Prostate Specific Antigen, CD26 and HtrA: A New Form of Immunosuppression?
Front Immunol
; 13: 832989, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35371018
9.
Modulation of immune cell function, IDO expression and kynurenine production by the quorum sensor 2-heptyl-3-hydroxy-4-quinolone (PQS).
Front Immunol
; 13: 1001956, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36389710
10.
IDO and Kynurenine Metabolites in Peripheral and CNS Disorders.
Front Immunol
; 11: 388, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32194572
11.
IDO activation, inflammation and musculoskeletal disease.
Exp Gerontol
; 131: 110820, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31884118
12.
cIAP1/2 inhibition synergizes with TNF inhibition in autoimmunity by down-regulating IL-17A and inducing Tregs.
Sci Adv
; 5(5): eaaw5422, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31049403
13.
Inhibition of Sec61-dependent translocation by mycolactone uncouples the integrated stress response from ER stress, driving cytotoxicity via translational activation of ATF4.
Cell Death Dis
; 9(3): 397, 2018 03 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29540678