Pesquisa | Portal de Pesquisa da BVS

1.

STAT5 interferes with PD-1 transcriptional activation and affects CD8+ T-cell sensitivity to PD-1-dependent immunoregulation.

Wang, Guanning; Tajima, Masaki; Honjo, Tasuku; Ohta, Akio.

Int Immunol ; 33(11): 563-572, 2021 10 29.

Artigo em Inglês | MEDLINE | ID: mdl-34453440

2.

Local Cross-Coupling Activity of Azide-Hexa(ethylene glycol)-Terminated Self-Assembled Monolayers Investigated by Atomic Force Microscopy.

Lebitania, Julie Ann; Inada, Natsumi; Morimoto, Masayuki; You, Jiaxun; Shahiduzzaman, Md; Taima, Tetsuya; Hirata, Kaito; Fukuma, Takeshi; Ohta, Akio; Asakawa, Tsuyoshi; Asakawa, Hitoshi.

Langmuir ; 37(50): 14688-14696, 2021 12 21.

Artigo em Inglês | MEDLINE | ID: mdl-34878277

3.

A_2A Adenosine Receptor Gene Deletion or Synthetic A_2A Antagonist Liberate Tumor-Reactive CD8⁺ T Cells from Tumor-Induced Immunosuppression.

Kjaergaard, Jorgen; Hatfield, Stephen; Jones, Graham; Ohta, Akio; Sitkovsky, Michail.

J Immunol ; 201(2): 782-791, 2018 07 15.

Artigo em Inglês | MEDLINE | ID: mdl-29802128

4.

Oxygen-dependent regulation of immune checkpoint mechanisms.

Ohta, Akio.

Int Immunol ; 30(8): 335-343, 2018 07 24.

Artigo em Inglês | MEDLINE | ID: mdl-29846615

5.

The GS Protein-coupled A2a Adenosine Receptor Controls T Cell Help in the Germinal Center.

Abbott, Robert K; Silva, Murillo; Labuda, Jasmine; Thayer, Molly; Cain, Derek W; Philbrook, Phaethon; Sethumadhavan, Shalini; Hatfield, Stephen; Ohta, Akio; Sitkovsky, Michail.

J Biol Chem ; 292(4): 1211-1217, 2017 01 27.

Artigo em Inglês | MEDLINE | ID: mdl-27974461

6.

Germinal Center Hypoxia Potentiates Immunoglobulin Class Switch Recombination.

Abbott, Robert K; Thayer, Molly; Labuda, Jasmine; Silva, Murillo; Philbrook, Phaethon; Cain, Derek W; Kojima, Hidefumi; Hatfield, Stephen; Sethumadhavan, Shalini; Ohta, Akio; Reinherz, Ellis L; Kelsoe, Garnett; Sitkovsky, Michail.

J Immunol ; 197(10): 4014-4020, 2016 11 15.

Artigo em Inglês | MEDLINE | ID: mdl-27798169

7.

Extracellular adenosine controls NKT-cell-dependent hepatitis induction.

Subramanian, Meenakshi; Kini, Radhika; Madasu, Manasa; Ohta, Akiko; Nowak, Michael; Exley, Mark; Sitkovsky, Michail; Ohta, Akio.

Eur J Immunol ; 44(4): 1119-29, 2014 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-24448964

8.

Hypoxia-induced and A2A adenosine receptor-independent T-cell suppression is short lived and easily reversible.

Ohta, Akio; Madasu, Manasa; Subramanian, Meenakshi; Kini, Radhika; Jones, Graham; Choukèr, Alexander; Ohta, Akiko; Sitkovsky, Michail.

Int Immunol ; 26(2): 83-91, 2014 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-24150242

9.

[Biguanide].

Ohta, Akio; Tanaka, Yasushi.

Nihon Rinsho ; 73(3): 397-401, 2015 Mar.

Artigo em Japonês | MEDLINE | ID: mdl-25812364

10.

Genetic deletion of the HIF-1α isoform I.1 in T cells enhances antibacterial immunity and improves survival in a murine peritonitis model.

Georgiev, Peter; Belikoff, Bryan G; Hatfield, Stephen; Ohta, Akio; Sitkovsky, Michail V; Lukashev, Dmitriy.

Eur J Immunol ; 43(3): 655-66, 2013 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-23208786

11.

Postoperative hyperoxia (60%) worsens hepatic injury in mice.

Zangl, Quirin; Martignoni, André; Jackson, Sharon H; Ohta, Akio; Klaunberg, Brenda; Kaufmann, Ines; Lukashev, Dimitry; Ward, Jerrold M; Sitkovsky, Michail; Thiel, Manfred; Choukèr, Alexander.

Anesthesiology ; 121(6): 1217-25, 2014 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-25225820

12.

Effect of sitagliptin on glycemic control and beta cell function in Japanese patients given basal-supported oral therapy for type 2 diabetes.

Asai, Shiko; Ohta, Akio; Kato, Hiroyuki; Sada, Yoshiyuki; Nagai, Yoshio; Kondo, Akihiko; Sasaoka, Toshiyasu; Tanaka, Yasushi.

Endocr J ; 61(12): 1213-20, 2014.

Artigo em Inglês | MEDLINE | ID: mdl-25231694

13.

Effect of insulin glargine on endogenous insulin secretion and beta-cell function in Japanese type 2 diabetic patients using oral antidiabetic drugs.

Ohta, Akio; Kato, Hiroyuki; Murayama, Katura; Hashimoto, Eriko; Murakami, Mariko; Nishine, Ami; Ohshige, Toshihiko; Sada, Yoshiyuki; Asai, Shiko; Kawata, Takehiro; Nagai, Yoshio; Katabami, Takuyuki; Tanaka, Yasushi.

Endocr J ; 61(1): 13-8, 2014.

Artigo em Inglês | MEDLINE | ID: mdl-24064478

14.

Remediation of cadmium-contaminated soil: GLDA-assisted extraction and sequential FeCl₃-CaO-based post-stabilization.

Ni, Shengbin; Rahman, Shafiqur; Harada, Yasuhiro; Yoshioka, Shoji; Imaizumi, Minami; Wong, Kuo H; Mashio, Asami S; Ohta, Akio; Hasegawa, Hiroshi.

Chemosphere ; 346: 140554, 2024 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-38303381

15.

Plasminogen activator inhibitor-1 promotes immune evasion in tumors by facilitating the expression of programmed cell death-ligand 1.

Ibrahim, Abd Aziz; Fujimura, Taku; Uno, Tomoko; Terada, Tomoya; Hirano, Ken-Ichi; Hosokawa, Hiroyuki; Ohta, Akio; Miyata, Toshio; Ando, Kiyoshi; Yahata, Takashi.

Front Immunol ; 15: 1365894, 2024.

Artigo em Inglês | MEDLINE | ID: mdl-38779680

16.

A2B adenosine receptor blockade enhances macrophage-mediated bacterial phagocytosis and improves polymicrobial sepsis survival in mice.

Belikoff, Bryan G; Hatfield, Stephen; Georgiev, Peter; Ohta, Akio; Lukashev, Dmitriy; Buras, Jon A; Remick, Daniel G; Sitkovsky, Michail.

J Immunol ; 186(4): 2444-53, 2011 Feb 15.

Artigo em Inglês | MEDLINE | ID: mdl-21242513

17.

Comparison of daily glucose excursion by continuous glucose monitoring between type 2 diabetic patients receiving preprandial insulin aspart or postprandial insulin glulisine.

Ohta, Akio; Arai, Kaori; Nishine, Ami; Sada, Yoshiyuki; Kato, Hiroyuki; Fukuda, Hisashi; Asai, Shiko; Nagai, Yoshio; Katabami, Takuyuki; Tanaka, Yasushi.

Endocr J ; 60(2): 173-7, 2013.

Artigo em Inglês | MEDLINE | ID: mdl-23047542

18.

Anti-PD-1 antibodies recognizing the membrane-proximal region are PD-1 agonists that can down-regulate inflammatory diseases.

Suzuki, Kensuke; Tajima, Masaki; Tokumaru, Yosuke; Oshiro, Yuya; Nagata, Satoshi; Kamada, Haruhiko; Kihara, Miho; Nakano, Kohei; Honjo, Tasuku; Ohta, Akio.

Sci Immunol ; 8(79): eadd4947, 2023 01 13.

Artigo em Inglês | MEDLINE | ID: mdl-36638191

19.

Evaluation of newly designed flushing techniques for on-site remediation of arsenic-contaminated excavated debris.

Rahman, Shafiqur; Saito, Makoto; Yoshioka, Shoji; Ni, Shengbin; Wong, Kuo H; Mashio, Asami S; Begum, Zinnat A; Rahman, Ismail M M; Ohta, Akio; Hasegawa, Hiroshi.

Environ Sci Pollut Res Int ; 30(52): 112052-112070, 2023 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-37824052

20.

Cell-compatible isotonic freezing media enabled by thermo-responsive osmolyte-adsorption/exclusion polymer matrices.

Kato, Yui; Matsuda, Yuya; Uto, Takuya; Tanaka, Daisuke; Ishibashi, Kojiro; Ishizaki, Takeru; Ohta, Akio; Kobayashi, Akiko; Hazawa, Masaharu; Wong, Richard W; Ninomiya, Kazuaki; Takahashi, Kenji; Hirata, Eishu; Kuroda, Kosuke.

Commun Chem ; 6(1): 260, 2023 Nov 29.

Artigo em Inglês | MEDLINE | ID: mdl-38030701

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