RESUMO
INTRODUCTION: Donovanosis (granuloma inguinale) is a bacterial infection caused by Klebsiella granulomatis that occurs mainly in the genital area and is primarily sexually transmitted; it is seen predominantly in the tropics. Herein, we report a case of the disease contracted in metropolitan France. PATIENTS AND METHODS: A 47-year-old man presented with painless ulceration of the glans, present for one month, with progressive extension; there was no history of any recent trip abroad. Skin biopsy with Whartin-Starry and Giemsa staining revealed Donovan bodies in the cytoplasm of macrophages. Based on these findings, further questioning of the patient revealed unprotected sexual contact two months earlier in France. Treatment was initiated with azithromycin 1g on the first day followed by 500mg per day for three weeks. The clinical outcome was spectacular, with almost complete regression of the ulcer at 7 days. DISCUSSION: This case demonstrates that donovanosis can occur in metropolitan France.
Assuntos
Granuloma Inguinal/diagnóstico , Doenças do Pênis/microbiologia , Citoplasma/microbiologia , França , Humanos , Macrófagos/citologia , Macrófagos/microbiologia , Masculino , Pessoa de Meia-IdadeAssuntos
Exantema , Fasciite Necrosante , Exantema/etiologia , Humanos , Cirrose Hepática/complicaçõesRESUMO
Epidermoid cyst is a benign and rare tumor, that evolves slowly. We describe the case of a 55 years-old woman, who came to our consultation for atypical trigeminal neuralgia of left V1 and V2 nerves. Brain MRI found two tumors: T1W hypointense with no appreciable enhancement after gadolinium injection and T2W and diffusion hyperintense. This last feature was in favour of an epidermoid cyst, but the multiplicity of cerebral lesions was definitely not in favor of such a diagnostic. They were located behind the right eye and in the left Meckel's cave (trigeminal cave). The surgical strategy consisted in removal the retro orbital tumor witch was the most accessible of both the diagnostic of epidermoid cyst was retaned thanks to the anatomopathology report. As these lesions had the exact same characteristics, we concluded that they were similar. The second epidermoid cyst was not removed because of surgical risk, its benign nature and low evolutionary potential.