Detalhe da pesquisa
1.
Schistosoma mansoni α-N-acetylgalactosaminidase (SmNAGAL) regulates coordinated parasite movement and egg production.
PLoS Pathog
; 18(1): e1009828, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35025955
2.
Histone methylation changes are required for life cycle progression in the human parasite Schistosoma mansoni.
PLoS Pathog
; 14(5): e1007066, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29782530
3.
Quinoxaline-Based Anti-Schistosomal Compounds Have Potent Anti-Malarial Activity.
bioRxiv
; 2024 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38712185
4.
Using ChEMBL to Complement Schistosome Drug Discovery.
Pharmaceutics
; 15(5)2023 Apr 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37242601
5.
Small Molecule Ligands of the BET-like Bromodomain, SmBRD3, Affect Schistosoma mansoni Survival, Oviposition, and Development.
J Med Chem
; 66(23): 15801-15822, 2023 12 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38048437
6.
Chemical modulation of Schistosoma mansoni lysine specific demethylase 1 (SmLSD1) induces wide-scale biological and epigenomic changes.
Wellcome Open Res
; 8: 146, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37520936
7.
Modified Hederagenin Derivatives Demonstrate Ex Vivo Anthelmintic Activity against Fasciola hepatica.
Pharmaceutics
; 15(7)2023 Jul 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37514055
8.
Perspective on Schistosomiasis Drug Discovery: Highlights from a Schistosomiasis Drug Discovery Workshop at Wellcome Collection, London, September 2022.
ACS Infect Dis
; 9(5): 1046-1055, 2023 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37083395
9.
Identification of anti-schistosomal, anthelmintic and anti-parasitic compounds curated and text-mined from the scientific literature.
Wellcome Open Res
; 7: 193, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36003342
10.
Flukicidal effects of abietane diterpenoid derived analogues against the food borne pathogen Fasciola hepatica.
Vet Parasitol
; 309: 109766, 2022 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-35926239
11.
Structural Investigations on Novel Non-Nucleoside Inhibitors of Human Norovirus Polymerase.
Viruses
; 15(1)2022 12 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36680114
12.
Schistosoma mansoni Larval Extracellular Vesicle protein 1 (SmLEV1) is an immunogenic antigen found in EVs released from pre-acetabular glands of invading cercariae.
PLoS Negl Trop Dis
; 15(11): e0009981, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34793443
13.
Anti-schistosomal activities of quinoxaline-containing compounds: From hit identification to lead optimisation.
Eur J Med Chem
; 226: 113823, 2021 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34536671
14.
Identification of 6-(piperazin-1-yl)-1,3,5-triazine as a chemical scaffold with broad anti-schistosomal activities.
Wellcome Open Res
; 5: 169, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32904763
15.
Large-scale RNAi screening uncovers therapeutic targets in the parasite Schistosoma mansoni.
Science
; 369(6511): 1649-1653, 2020 09 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32973031
16.
The repositioning of epigenetic probes/inhibitors identifies new anti-schistosomal lead compounds and chemotherapeutic targets.
PLoS Negl Trop Dis
; 13(11): e0007693, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31730617
17.
Combining bioinformatics, cheminformatics, functional genomics and whole organism approaches for identifying epigenetic drug targets in Schistosoma mansoni.
Int J Parasitol Drugs Drug Resist
; 8(3): 559-570, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30455056
18.
(Epi)genetic Inheritance in Schistosoma mansoni: A Systems Approach.
Trends Parasitol
; 33(4): 285-294, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28040375
19.
Erratum to 'Combining bioinformatics, cheminformatics, functional genomics and whole organism approaches for identifying epigenetic drug targets in Schistosoma mansoni' [IJP Drugs Drug Resist. 8 (2018) 559-570].
Int J Parasitol Drugs Drug Resist
; 10: 91, 2019 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-31299537