Detalhe da pesquisa
1.
7-tert-Butyl-6-(4-chloro-phenyl)-2-thioxo-2,3-dihydro-1H-pyrido[2,3-d]pyrimidin-4-one, a classic polymodal inhibitor of transient receptor potential vanilloid type 1 with a reduced liability for hyperthermia, is analgesic and ameliorates visceral hypersensitivity.
J Pharmacol Exp Ther
; 342(2): 389-98, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22566669
2.
STING regulates peripheral nerve regeneration and colony stimulating factor 1 receptor (CSF1R) processing in microglia.
iScience
; 24(12): 103434, 2021 Dec 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34877494
3.
Magnetic Resonance Imaging as a Biomarker in Rodent Peripheral Nerve Injury Models Reveals an Age-Related Impairment of Nerve Regeneration.
Sci Rep
; 9(1): 13508, 2019 09 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31534149
4.
Modulation of Microglia by Voluntary Exercise or CSF1R Inhibition Prevents Age-Related Loss of Functional Motor Units.
Cell Rep
; 29(6): 1539-1554.e7, 2019 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31693894
5.
Identification and biological characterization of 6-aryl-7-isopropylquinazolinones as novel TRPV1 antagonists that are effective in models of chronic pain.
J Med Chem
; 49(2): 471-4, 2006 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-16420034
6.
Antihyperalgesic activity of a novel nonpeptide bradykinin B1 receptor antagonist in transgenic mice expressing the human B1 receptor.
Br J Pharmacol
; 144(7): 889-99, 2005 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15685199
7.
In vivo pharmacology of SDZ 249-665, a novel, non-pungent capsaicin analogue.
Pain
; 89(1): 65-74, 2000 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-11113294
8.
Discovery, optimization, and biological evaluation of 5-(2-(trifluoromethyl)phenyl)indazoles as a novel class of transient receptor potential A1 (TRPA1) antagonists.
J Med Chem
; 57(12): 5129-40, 2014 Jun 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-24884675
9.
Increased prokineticin 2 expression in gut inflammation: role in visceral pain and intestinal ion transport.
Neurogastroenterol Motil
; 24(1): 65-75, e12, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22050240