Detalhe da pesquisa
1.
Using patient-derived tumor organoids from common epithelial cancers to analyze personalized T-cell responses to neoantigens.
Cancer Immunol Immunother
; 72(10): 3149-3162, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37368077
2.
Stable, Nonviral Expression of Mutated Tumor Neoantigen-specific T-cell Receptors Using the Sleeping Beauty Transposon/Transposase System.
Mol Ther
; 24(6): 1078-1089, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26945006
3.
A TCR targeting the HLA-A*0201-restricted epitope of MAGE-A3 recognizes multiple epitopes of the MAGE-A antigen superfamily in several types of cancer.
J Immunol
; 186(2): 685-96, 2011 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21149604
4.
Adoptive cell transfer immunotherapy for patients with solid epithelial cancers.
Cancer Cell
; 41(4): 646-648, 2023 04 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37037613
5.
Phenotypic signatures of circulating neoantigen-reactive CD8+ T cells in patients with metastatic cancers.
Cancer Cell
; 41(12): 2154-2165.e5, 2023 12 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38039963
6.
Clinical scale rapid expansion of lymphocytes for adoptive cell transfer therapy in the WAVE® bioreactor.
J Transl Med
; 10: 69, 2012 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-22475724
7.
T cells targeting carcinoembryonic antigen can mediate regression of metastatic colorectal cancer but induce severe transient colitis.
Mol Ther
; 19(3): 620-6, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21157437
8.
A phenotypic signature that identifies neoantigen-reactive T cells in fresh human lung cancers.
Cancer Cell
; 40(5): 479-493.e6, 2022 05 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35452604
9.
Breast Cancers Are Immunogenic: Immunologic Analyses and a Phase II Pilot Clinical Trial Using Mutation-Reactive Autologous Lymphocytes.
J Clin Oncol
; 40(16): 1741-1754, 2022 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35104158
10.
Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade.
Med
; 3(10): 682-704.e8, 2022 10 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36007524
11.
Molecular signatures of antitumor neoantigen-reactive T cells from metastatic human cancers.
Science
; 375(6583): 877-884, 2022 02 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35113651
12.
Adoptive Cellular Therapy with Autologous Tumor-Infiltrating Lymphocytes and T-cell Receptor-Engineered T Cells Targeting Common p53 Neoantigens in Human Solid Tumors.
Cancer Immunol Res
; 10(8): 932-946, 2022 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35749374
13.
Identification and Validation of T-cell Receptors Targeting RAS Hotspot Mutations in Human Cancers for Use in Cell-based Immunotherapy.
Clin Cancer Res
; 27(18): 5084-5095, 2021 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34168045
14.
A machine learning model for ranking candidate HLA class I neoantigens based on known neoepitopes from multiple human tumor types.
Nat Cancer
; 2(5): 563-574, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34927080
15.
Rapid Identification and Evaluation of Neoantigen-reactive T-Cell Receptors From Single Cells.
J Immunother
; 44(1): 1-8, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33086340
16.
Characterization of genetically modified T-cell receptors that recognize the CEA:691-699 peptide in the context of HLA-A2.1 on human colorectal cancer cells.
Clin Cancer Res
; 15(1): 169-80, 2009 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19118044
17.
mRNA vaccine-induced neoantigen-specific T cell immunity in patients with gastrointestinal cancer.
J Clin Invest
; 130(11): 5976-5988, 2020 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33016924
18.
Stem-like CD8 T cells mediate response of adoptive cell immunotherapy against human cancer.
Science
; 370(6522): 1328-1334, 2020 12 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33303615
19.
Antigen Experienced T Cells from Peripheral Blood Recognize p53 Neoantigens.
Clin Cancer Res
; 26(6): 1267-1276, 2020 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31996390
20.
Extrathymic generation of tumor-specific T cells from genetically engineered human hematopoietic stem cells via Notch signaling.
Cancer Res
; 67(6): 2425-9, 2007 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17363559