Detalhe da pesquisa
1.
Structure-based design, synthesis and biological evaluation of a novel series of isoquinolone and pyrazolo[4,3-c]pyridine inhibitors of fascin 1 as potential anti-metastatic agents.
Bioorg Med Chem Lett
; 29(8): 1023-1029, 2019 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30773430
2.
CYRI-B mediated macropinocytosis drives metastasis via lysophosphatidic acid receptor uptake.
Elife
; 132024 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38712822
3.
A nanobody inhibitor of Fascin-1 actin-bundling activity and filopodia formation.
Open Biol
; 14(3): 230376, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38503329
4.
Cancer-associated fibroblasts produce matrix-bound vesicles that influence endothelial cell function.
Sci Signal
; 17(827): eade0580, 2024 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38470957
5.
NUAK1 governs centrosome replication in pancreatic cancer via MYPT1/PP1ß and GSK3ß-dependent regulation of PLK4.
Mol Oncol
; 17(7): 1212-1227, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36975767
6.
Increased apoptotic sensitivity of glioblastoma enables therapeutic targeting by BH3-mimetics.
Cell Death Differ
; 29(10): 2089-2104, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35473984
7.
CYRI-A limits invasive migration through macropinosome formation and integrin uptake regulation.
J Cell Biol
; 220(9)2021 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34165494
8.
An evaluation of multi-excitation-wavelength standing-wave fluorescence microscopy (TartanSW) to improve sampling density in studies of the cell membrane and cytoskeleton.
Sci Rep
; 11(1): 2903, 2021 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33536463
9.
The creatine-phosphagen system is mechanoresponsive in pancreatic adenocarcinoma and fuels invasion and metastasis.
Nat Metab
; 2(1): 62-80, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32694686
10.
Adhesion and growth factor receptor crosstalk mechanisms controlling cell migration.
Essays Biochem
; 63(5): 553-567, 2019 10 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-31551325
11.
CYRI/ Fam49 Proteins Represent a New Class of Rac1 Interactors.
Commun Integr Biol
; 12(1): 112-118, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31413787
12.
Characterization of the Phospho-Adhesome by Mass Spectrometry-Based Proteomics.
Methods Mol Biol
; 1636: 235-251, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28730483
13.
Coordination by Cdc42 of Actin, Contractility, and Adhesion for Melanoblast Movement in Mouse Skin.
Curr Biol
; 27(5): 624-637, 2017 Mar 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28238662
14.
Endocytic Trafficking of Integrins in Cell Migration.
Curr Biol
; 25(22): R1092-105, 2015 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-26583903
15.
Emerging properties of adhesion complexes: what are they and what do they do?
Trends Cell Biol
; 25(7): 388-97, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25824971
16.
Isolation of integrin-based adhesion complexes.
Curr Protoc Cell Biol
; 66: 9.8.1-9.8.15, 2015 Mar 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-25727331
17.
Definition of a consensus integrin adhesome and its dynamics during adhesion complex assembly and disassembly.
Nat Cell Biol
; 17(12): 1577-1587, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26479319
18.
α5ß1 integrin recycling promotes Arp2/3-independent cancer cell invasion via the formin FHOD3.
J Cell Biol
; 210(6): 1013-31, 2015 Sep 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26370503