Detalhe da pesquisa
1.
P-TEFb: The master regulator of transcription elongation.
Mol Cell
; 83(3): 393-403, 2023 02 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36599353
2.
Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma.
Mol Cell
; 62(1): 34-46, 2016 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27058786
3.
P-TEFb is degraded by Siah1/2 in quiescent cells.
Nucleic Acids Res
; 50(9): 5000-5013, 2022 05 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35524561
4.
HEXIM1-Tat chimera inhibits HIV-1 replication.
PLoS Pathog
; 14(11): e1007402, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30395647
5.
Fab-based inhibitors reveal ubiquitin independent functions for HIV Vif neutralization of APOBEC3 restriction factors.
PLoS Pathog
; 14(1): e1006830, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29304101
6.
Bromodomain-containing protein 4-independent transcriptional activation by autoimmune regulator (AIRE) and NF-κB.
J Biol Chem
; 293(14): 4993-5004, 2018 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29463681
7.
The Cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genes.
Genes Dev
; 25(20): 2158-72, 2011 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22012619
8.
Hili Inhibits HIV Replication in Activated T Cells.
J Virol
; 91(11)2017 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28331090
9.
FBXO3 Protein Promotes Ubiquitylation and Transcriptional Activity of AIRE (Autoimmune Regulator).
J Biol Chem
; 291(34): 17953-63, 2016 08 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27365398
10.
An In-Depth Comparison of Latency-Reversing Agent Combinations in Various In Vitro and Ex Vivo HIV-1 Latency Models Identified Bryostatin-1+JQ1 and Ingenol-B+JQ1 to Potently Reactivate Viral Gene Expression.
PLoS Pathog
; 11(7): e1005063, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26225566
11.
Visualization of positive transcription elongation factor b (P-TEFb) activation in living cells.
J Biol Chem
; 290(3): 1829-36, 2015 Jan 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-25492871
12.
Tat-SIRT1 tango.
Mol Cell
; 29(5): 539-40, 2008 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-18342601
13.
Genetic analysis of the structure and function of 7SK small nuclear ribonucleoprotein (snRNP) in cells.
J Biol Chem
; 289(30): 21181-90, 2014 Jul 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-24917669
14.
Release of positive transcription elongation factor b (P-TEFb) from 7SK small nuclear ribonucleoprotein (snRNP) activates hexamethylene bisacetamide-inducible protein (HEXIM1) transcription.
J Biol Chem
; 289(14): 9918-25, 2014 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-24515107
15.
The mechanism of tissue-restricted antigen gene expression by AIRE.
J Immunol
; 190(6): 2479-82, 2013 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23456700
16.
Hide, shield and strike back: how HIV-infected cells avoid immune eradication.
Nat Rev Immunol
; 3(2): 97-107, 2003 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-12563294
17.
Histone deacetylase inhibitors (HDACis) that release the positive transcription elongation factor b (P-TEFb) from its inhibitory complex also activate HIV transcription.
J Biol Chem
; 288(20): 14400-14407, 2013 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-23539624
18.
PKC phosphorylates HEXIM1 and regulates P-TEFb activity.
Nucleic Acids Res
; 40(18): 9160-70, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22821562
19.
Bromodomain and extra-terminal (BET) bromodomain inhibition activate transcription via transient release of positive transcription elongation factor b (P-TEFb) from 7SK small nuclear ribonucleoprotein.
J Biol Chem
; 287(43): 36609-16, 2012 Oct 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-22952229
20.
Moloney leukemia virus type 10 inhibits reverse transcription and retrotransposition of intracisternal a particles.
J Virol
; 86(19): 10517-23, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22811528