Detalhe da pesquisa
1.
Multiple copies of the oxytetracycline gene cluster in selected Streptomyces rimosus strains can provide significantly increased titers.
Microb Cell Fact
; 20(1): 47, 2021 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33596911
2.
Antiviral Activities of Halogenated Emodin Derivatives against Human Coronavirus NL63.
Molecules
; 26(22)2021 Nov 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34833917
3.
Comparison of Proteomic Responses as Global Approach to Antibiotic Mechanism of Action Elucidation.
Antimicrob Agents Chemother
; 65(1)2020 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33046497
4.
Heterologous expression of the atypical tetracycline chelocardin reveals the full set of genes required for its biosynthesis.
Microb Cell Fact
; 19(1): 230, 2020 Dec 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33341113
5.
Extracellular production of the engineered thermostable protease pernisine from Aeropyrum pernix K1 in Streptomyces rimosus.
Microb Cell Fact
; 18(1): 196, 2019 Nov 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31699090
6.
The Novel Transcriptional Regulator LmbU Promotes Lincomycin Biosynthesis through Regulating Expression of Its Target Genes in Streptomyces lincolnensis.
J Bacteriol
; 200(2)2018 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29038257
7.
Production of extracellular heterologous proteins in Streptomyces rimosus, producer of the antibiotic oxytetracycline.
Appl Microbiol Biotechnol
; 102(6): 2607-2620, 2018 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-29417200
8.
Dual mechanism of action of the atypical tetracycline chelocardin.
Biochim Biophys Acta
; 1864(6): 645-654, 2016 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-26969785
9.
Strategies for the Discovery and Development of New Antibiotics from Natural Products: Three Case Studies.
Curr Top Microbiol Immunol
; 398: 339-363, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27738913
10.
Extracellular 4'-phosphopantetheine is a source for intracellular coenzyme A synthesis.
Nat Chem Biol
; 11(10): 784-92, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26322826
11.
In Saccharomyces cerevisiae gene targeting fidelity depends on a transformation method and proportion of the overall length of the transforming and targeted DNA.
FEMS Yeast Res
; 17(4)2017 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28633406
12.
Biosynthesis of Oxytetracycline by Streptomyces rimosus:Past, Present and Future Directions in the Developmentof Tetracycline Antibiotics.
Food Technol Biotechnol
; 55(1): 3-13, 2017 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-28559729
13.
Integrated omics approaches provide strategies for rapid erythromycin yield increase in Saccharopolyspora erythraea.
Microb Cell Fact
; 15: 93, 2016 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27255285
14.
Roles of the crotonyl-CoA carboxylase/reductase homologues in acetate assimilation and biosynthesis of immunosuppressant FK506 in Streptomyces tsukubaensis.
Microb Cell Fact
; 14: 164, 2015 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26466669
15.
Rapid identification of atypical tetracyclines using tandem mass spectrometric fragmentation patterns.
Rapid Commun Mass Spectrom
; 29(17): 1556-1562, 2015 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28339151
16.
Construction of a new class of tetracycline lead structures with potent antibacterial activity through biosynthetic engineering.
Angew Chem Int Ed Engl
; 54(13): 3937-40, 2015 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25650563
17.
Oxytetracycline hyper-production through targeted genome reduction of Streptomyces rimosus.
mSystems
; 9(5): e0025024, 2024 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38564716
18.
Erratum for Hou et al., "The Novel Transcriptional Regulator LmbU Promotes Lincomycin Biosynthesis through Regulating Expression of Its Target Genes in Streptomyces lincolnensis".
J Bacteriol
; 200(5)2018 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29437796
19.
Identification of the chelocardin biosynthetic gene cluster from Amycolatopsis sulphurea: a platform for producing novel tetracycline antibiotics.
Microbiology (Reading)
; 159(Pt 12): 2524-2532, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24043447
20.
Recombinant strains for the enhanced production of bioengineered rapalogs.
Metab Eng
; 15: 167-73, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23164580