Detalhe da pesquisa
1.
Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malaria.
Proc Natl Acad Sci U S A
; 109(21): 8298-303, 2012 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-22566611
2.
Targeting the Ubiquinol-Reduction (Qi) Site of the Mitochondrial Cytochrome bc1 Complex for the Development of Next Generation Quinolone Antimalarials.
Biology (Basel)
; 11(8)2022 Jul 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35892964
3.
Second-generation nitazoxanide derivatives: thiazolides are effective inhibitors of the influenza A virus.
Future Med Chem
; 10(8): 851-862, 2018 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29629834
4.
A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance.
Nat Commun
; 8: 15159, 2017 05 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28537265
5.
Targeting the mitochondrial electron transport chain of Plasmodium falciparum: new strategies towards the development of improved antimalarials for the elimination era.
Future Med Chem
; 5(13): 1573-91, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24024949
6.
Identification, design and biological evaluation of bisaryl quinolones targeting Plasmodium falciparum type II NADH:quinone oxidoreductase (PfNDH2).
J Med Chem
; 55(5): 1831-43, 2012 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-22364416
7.
Identification, design and biological evaluation of heterocyclic quinolones targeting Plasmodium falciparum type II NADH:quinone oxidoreductase (PfNDH2).
J Med Chem
; 55(5): 1844-57, 2012 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-22364417
8.
Identification of novel antimalarial chemotypes via chemoinformatic compound selection methods for a high-throughput screening program against the novel malarial target, PfNDH2: increasing hit rate via virtual screening methods.
J Med Chem
; 55(7): 3144-54, 2012 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-22380711
9.
Thiazolides as novel antiviral agents. 1. Inhibition of hepatitis B virus replication.
J Med Chem
; 54(12): 4119-32, 2011 Jun 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-21553812
10.
Thiazolides as novel antiviral agents. 2. Inhibition of hepatitis C virus replication.
J Med Chem
; 54(24): 8670-80, 2011 Dec 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-22059983
11.
Direct catalytic asymmetric enolexo aldolizations.
Angew Chem Int Ed Engl
; 42(24): 2785-8, 2003 Jun 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-12820268
12.
In vitro efficacies of nitazoxanide and other thiazolides against Neospora caninum tachyzoites reveal antiparasitic activity independent of the nitro group.
Antimicrob Agents Chemother
; 49(9): 3715-23, 2005 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16127045