Detalhe da pesquisa
1.
Structure of the thrombopoietin-MPL receptor complex is a blueprint for biasing hematopoiesis.
Cell
; 186(19): 4189-4203.e22, 2023 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37633268
2.
Decoupling the Functional Pleiotropy of Stem Cell Factor by Tuning c-Kit Signaling.
Cell
; 168(6): 1041-1052.e18, 2017 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28283060
3.
Functional Selectivity in Cytokine Signaling Revealed Through a Pathogenic EPO Mutation.
Cell
; 168(6): 1053-1064.e15, 2017 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28283061
4.
Structure of the interleukin-5 receptor complex exemplifies the organizing principle of common beta cytokine signaling.
Mol Cell
; 84(10): 1995-2005.e7, 2024 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38614096
5.
Tuning cytokine receptor signaling by re-orienting dimer geometry with surrogate ligands.
Cell
; 160(6): 1196-208, 2015 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25728669
6.
Organizing structural principles of the IL-17 ligand-receptor axis.
Nature
; 609(7927): 622-629, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35863378
7.
Plasma membrane topography governs the 3D dynamic localization of IgM B cell antigen receptor clusters.
EMBO J
; 42(4): e112030, 2023 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36594262
8.
Structural linkage between ligand discrimination and receptor activation by type I interferons.
Cell
; 146(4): 621-32, 2011 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-21854986
9.
Structure of the IFNγ receptor complex guides design of biased agonists.
Nature
; 567(7746): 56-60, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30814731
10.
Dissociation of ß2m from MHC class I triggers formation of noncovalent transient heavy chain dimers.
J Cell Sci
; 135(9)2022 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35393611
11.
Tuning MPL signaling to influence hematopoietic stem cell differentiation and inhibit essential thrombocythemia progenitors.
Proc Natl Acad Sci U S A
; 118(2)2021 01 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33384332
12.
Rapid dynamics of general transcription factor TFIIB binding during preinitiation complex assembly revealed by single-molecule analysis.
Genes Dev
; 30(18): 2106-2118, 2016 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27798851
13.
Densely methylated DNA traps Methyl-CpG-binding domain protein 2 but permits free diffusion by Methyl-CpG-binding domain protein 3.
J Biol Chem
; 298(10): 102428, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36037972
14.
Surrogate Wnt agonists that phenocopy canonical Wnt and ß-catenin signalling.
Nature
; 545(7653): 234-237, 2017 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28467818
15.
TIN2 is an architectural protein that facilitates TRF2-mediated trans- and cis-interactions on telomeric DNA.
Nucleic Acids Res
; 49(22): 13000-13018, 2021 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34883513
16.
Type I IFN is siloed in endosomes.
Proc Natl Acad Sci U S A
; 117(30): 17510-17512, 2020 07 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32665439
17.
Reversible Live-Cell Labeling with Retro-engineered HaloTags Enables Long-Term High- and Super-Resolution Imaging.
Angew Chem Int Ed Engl
; 62(18): e202219050, 2023 04 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36735334
18.
Flexible open conformation of the AP-3 complex explains its role in cargo recruitment at the Golgi.
J Biol Chem
; 297(5): 101334, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34688652
19.
Structure, dynamics, and regulation of TRF1-TIN2-mediated trans- and cis-interactions on telomeric DNA.
J Biol Chem
; 297(3): 101080, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34403696
20.
Biofunctional Nanodot Arrays in Living Cells Uncover Synergistic Co-Condensation of Wnt Signalodroplets.
Small
; 18(50): e2203723, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36266931