Detalhe da pesquisa
1.
Rapid genomic changes by mineralotropic hormones and kinase SIK inhibition drive coordinated renal Cyp27b1 and Cyp24a1 expression via CREB modules.
J Biol Chem
; 298(11): 102559, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36183832
2.
Targeted genomic deletions identify diverse enhancer functions and generate a kidney-specific, endocrine-deficient Cyp27b1 pseudo-null mouse.
J Biol Chem
; 294(24): 9518-9535, 2019 06 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31053643
3.
A chromatin-based mechanism controls differential regulation of the cytochrome P450 gene Cyp24a1 in renal and non-renal tissues.
J Biol Chem
; 294(39): 14467-14481, 2019 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31439663
4.
A kidney-specific genetic control module in mice governs endocrine regulation of the cytochrome P450 gene Cyp27b1 essential for vitamin D3 activation.
J Biol Chem
; 292(42): 17541-17558, 2017 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28808057
5.
Epigenetic Plasticity Drives Adipogenic and Osteogenic Differentiation of Marrow-derived Mesenchymal Stem Cells.
J Biol Chem
; 291(34): 17829-47, 2016 08 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27402842
6.
Deletion of a Distal RANKL Gene Enhancer Delays Progression of Atherosclerotic Plaque Calcification in Hypercholesterolemic Mice.
J Cell Biochem
; 118(12): 4240-4253, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28419519
7.
Selective Distal Enhancer Control of the Mmp13 Gene Identified through Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR) Genomic Deletions.
J Biol Chem
; 290(17): 11093-107, 2015 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-25773540
8.
Mechanisms of Enhancer-mediated Hormonal Control of Vitamin D Receptor Gene Expression in Target Cells.
J Biol Chem
; 290(51): 30573-86, 2015 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26504088
9.
1,25-Dihydroxyvitamin D3 Controls a Cohort of Vitamin D Receptor Target Genes in the Proximal Intestine That Is Enriched for Calcium-regulating Components.
J Biol Chem
; 290(29): 18199-18215, 2015 Jul 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-26041780
10.
1,25-Dihydroxyvitamin D regulates expression of the tryptophan hydroxylase 2 and leptin genes: implication for behavioral influences of vitamin D.
FASEB J
; 29(9): 4023-35, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26071405
11.
Progestins inhibit calcitriol-induced CYP24A1 and synergistically inhibit ovarian cancer cell viability: An opportunity for chemoprevention.
Gynecol Oncol
; 143(1): 159-167, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27106018
12.
The RUNX2 cistrome in osteoblasts: characterization, down-regulation following differentiation, and relationship to gene expression.
J Biol Chem
; 289(23): 16016-31, 2014 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-24764292
13.
Genomic determinants of gene regulation by 1,25-dihydroxyvitamin D3 during osteoblast-lineage cell differentiation.
J Biol Chem
; 289(28): 19539-54, 2014 Jul 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-24891508
14.
Transcriptional regulation of the human TNFSF11 gene in T cells via a cell type-selective set of distal enhancers.
J Cell Biochem
; 116(2): 320-30, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25211367
15.
Genomic mechanisms controlling renal vitamin D metabolism.
J Steroid Biochem Mol Biol
; 228: 106252, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36657729
16.
Molecular insights into mineralotropic hormone inter-regulation.
Front Endocrinol (Lausanne)
; 14: 1213361, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37441497
17.
Genome-wide analyses of gene expression profile identify key genes and pathways involved in skeletal response to phosphate and 1,25-dihydroxyvitamin D3 in vivo.
J Steroid Biochem Mol Biol
; 232: 106335, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37245694
18.
Neuropilin 2 in osteoblasts regulates trabecular bone mass in male mice.
Front Endocrinol (Lausanne)
; 14: 1223021, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37600714
19.
Vitamin D receptor cross-talk with p63 signaling promotes epidermal cell fate.
J Steroid Biochem Mol Biol
; 232: 106352, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37330071
20.
A parathyroid hormone/salt-inducible kinase signaling axis controls renal vitamin D activation and organismal calcium homeostasis.
J Clin Invest
; 133(9)2023 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36862513