Detalhe da pesquisa
1.
Tuning cytokine receptor signaling by re-orienting dimer geometry with surrogate ligands.
Cell
; 160(6): 1196-208, 2015 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25728669
2.
Immunosuppression by Mutated Calreticulin Released from Malignant Cells.
Mol Cell
; 77(4): 748-760.e9, 2020 02 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31785928
3.
Secreted mutant calreticulins as rogue cytokines in myeloproliferative neoplasms.
Blood
; 141(8): 917-929, 2023 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36356299
4.
Inferring the initiation and development of myeloproliferative neoplasms.
Proc Natl Acad Sci U S A
; 119(37): e2120374119, 2022 09 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36083966
5.
Optimizing IFN Alpha Therapy against Myeloproliferative Neoplasms.
J Pharmacol Exp Ther
; 387(1): 31-43, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37391225
6.
CALR mutant protein rescues the response of MPL p.R464G variant associated with CAMT to eltrombopag.
Blood
; 138(6): 480-485, 2021 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34010413
7.
Dual role of EZH2 in megakaryocyte differentiation.
Blood
; 138(17): 1603-1614, 2021 10 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34115825
8.
Inferring the dynamics of mutated hematopoietic stem and progenitor cells induced by IFNα in myeloproliferative neoplasms.
Blood
; 138(22): 2231-2243, 2021 12 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34407546
9.
ANKRD26 is a new regulator of type I cytokine receptor signaling in normal and pathological hematopoiesis.
Haematologica
; 108(8): 2130-2145, 2023 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36794499
10.
An inherited gain-of-function risk allele in EPOR predisposes to familial JAK2V617F myeloproliferative neoplasms.
Br J Haematol
; 198(1): 131-136, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35355248
11.
Defective interaction of mutant calreticulin and SOCE in megakaryocytes from patients with myeloproliferative neoplasms.
Blood
; 135(2): 133-144, 2020 01 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31697806
12.
Description of a knock-in mouse model of JAK2V617F MPN emerging from a minority of mutated hematopoietic stem cells.
Blood
; 134(26): 2383-2387, 2019 12 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31697834
13.
Calreticulin mutants as oncogenic rogue chaperones for TpoR and traffic-defective pathogenic TpoR mutants.
Blood
; 133(25): 2669-2681, 2019 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30902807
14.
Disrupted filamin A/αIIbß3 interaction induces macrothrombocytopenia by increasing RhoA activity.
Blood
; 133(16): 1778-1788, 2019 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30602618
15.
Mutations in the SRP54 gene cause severe congenital neutropenia as well as Shwachman-Diamond-like syndrome.
Blood
; 132(12): 1318-1331, 2018 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29914977
16.
The double-edged sword of adenosine.
Haematologica
; 109(1): 13-15, 2024 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37470140
17.
Association of MPL K39N and R102P heterozygous germline mutations lead to hereditary thrombocytosis.
Am J Hematol
; 2024 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38752375
18.
IFN: Jekyll and Hyde.
Blood
; 137(3): 291-293, 2021 01 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33475740
19.
Calreticulin mutants in mice induce an MPL-dependent thrombocytosis with frequent progression to myelofibrosis.
Blood
; 127(10): 1317-24, 2016 Mar 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26608331
20.
Thrombopoietin receptor activation by myeloproliferative neoplasm associated calreticulin mutants.
Blood
; 127(10): 1325-35, 2016 Mar 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26668133