Detalhe da pesquisa
1.
Deciphering the LRRK code: LRRK1 and LRRK2 phosphorylate distinct Rab proteins and are regulated by diverse mechanisms.
Biochem J
; 478(3): 553-578, 2021 02 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33459343
2.
Endogenous Rab29 does not impact basal or stimulated LRRK2 pathway activity.
Biochem J
; 477(22): 4397-4423, 2020 11 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33135724
3.
Glycomic and Proteomic Changes in Aging Brain Nigrostriatal Pathway.
Mol Cell Proteomics
; 17(9): 1778-1787, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29915149
4.
Development of phospho-specific Rab protein antibodies to monitor in vivo activity of the LRRK2 Parkinson's disease kinase.
Biochem J
; 475(1): 1-22, 2018 01 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29127256
5.
The Parkinson's disease VPS35[D620N] mutation enhances LRRK2-mediated Rab protein phosphorylation in mouse and human.
Biochem J
; 475(11): 1861-1883, 2018 06 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29743203
6.
Subthalamic Nucleus Deep Brain Stimulation Employs trkB Signaling for Neuroprotection and Functional Restoration.
J Neurosci
; 37(28): 6786-6796, 2017 07 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28607168
7.
Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration.
J Neuroinflammation
; 15(1): 129, 2018 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29716614
8.
Correction to: Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration.
J Neuroinflammation
; 15(1): 169, 2018 May 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-29843738
9.
Galectin-1 in injured rat spinal cord: implications for macrophage phagocytosis and neural repair.
Mol Cell Neurosci
; 64: 84-94, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25542813
10.
Intrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degeneration.
Neurobiol Dis
; 82: 185-199, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26093169
11.
Development and characterization of phospho-ubiquitin antibodies to monitor PINK1-PRKN signaling in cells and tissue.
bioRxiv
; 2024 Jan 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38293125
12.
Development and characterization of phospho-ubiquitin antibodies to monitor PINK1-PRKN signaling in cells and tissue.
Autophagy
; : 1-16, 2024 May 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38802071
13.
The GBA1 D409V mutation exacerbates synuclein pathology to differing extents in two alpha-synuclein models.
Dis Model Mech
; 15(6)2022 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35419585
14.
A Summary of Phenotypes Observed in the In Vivo Rodent Alpha-Synuclein Preformed Fibril Model.
J Parkinsons Dis
; 11(4): 1555-1567, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34486988
15.
Decreased glucocerebrosidase activity and substrate accumulation of glycosphingolipids in a novel GBA1 D409V knock-in mouse model.
PLoS One
; 16(6): e0252325, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34106956
16.
The Michael J. Fox Foundation for Parkinson's Research Strategy to Advance Therapeutic Development of PINK1 and Parkin.
Biomolecules
; 9(8)2019 07 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31344817
17.
Generation of Alpha-Synuclein Preformed Fibrils from Monomers and Use In Vivo.
J Vis Exp
; (148)2019 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31205308
18.
The Michael J. Fox Foundation's quest for a cure for Parkinson's disease: an interview with Nicole Polinski.
Dis Model Mech
; 16(12)2023 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38116678
19.
Best Practices for Generating and Using Alpha-Synuclein Pre-Formed Fibrils to Model Parkinson's Disease in Rodents.
J Parkinsons Dis
; 8(2): 303-322, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29400668
20.
Subthalamic Nucleus Deep Brain Stimulation Does Not Modify the Functional Deficits or Axonopathy Induced by Nigrostriatal α-Synuclein Overexpression.
Sci Rep
; 7(1): 16356, 2017 11 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29180681