Detalhe da pesquisa
1.
Profiling amyloid-ß peptides as biomarkers for cerebral amyloid angiopathy.
J Neurochem
; 2024 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38362804
2.
Genetic Mapping of APP and Amyloid-ß Biology Modulation by Trisomy 21.
J Neurosci
; 42(33): 6453-6468, 2022 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35835549
3.
Cerebrospinal fluid biomarker panel of synaptic dysfunction in Alzheimer's disease and other neurodegenerative disorders.
Alzheimers Dement
; 19(5): 1775-1784, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36239248
4.
γ-Secretase modulators show selectivity for γ-secretase-mediated amyloid precursor protein intramembrane processing.
J Cell Mol Med
; 26(3): 880-892, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34931449
5.
Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain.
Mol Psychiatry
; 26(10): 5766-5788, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32647257
6.
Plasma amyloid-ß ratios in autosomal dominant Alzheimer's disease: the influence of genotype.
Brain
; 144(10): 2964-2970, 2021 11 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-33892504
7.
Population-based blood screening for preclinical Alzheimer's disease in a British birth cohort at age 70.
Brain
; 144(2): 434-449, 2021 03 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33479777
8.
Amyloid pathology and synaptic loss in pathological aging.
J Neurochem
; 159(2): 258-272, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34473357
9.
A multifactorial model of pathology for age of onset heterogeneity in familial Alzheimer's disease.
Acta Neuropathol
; 141(2): 217-233, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33319314
10.
Familial Alzheimer's disease patient-derived neurons reveal distinct mutation-specific effects on amyloid beta.
Mol Psychiatry
; 25(11): 2919-2931, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30980041
11.
Cerebrospinal fluid tau fragment correlates with tau PET: a candidate biomarker for tangle pathology.
Brain
; 143(2): 650-660, 2020 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31834365
12.
Identification of neurotoxic cross-linked amyloid-ß dimers in the Alzheimer's brain.
Brain
; 142(5): 1441-1457, 2019 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31032851
13.
Amyloid polymorphisms constitute distinct clouds of conformational variants in different etiological subtypes of Alzheimer's disease.
Proc Natl Acad Sci U S A
; 114(49): 13018-13023, 2017 12 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29158413
14.
First amyloid ß1-42 certified reference material for re-calibrating commercial immunoassays.
Alzheimers Dement
; 16(11): 1493-1503, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32755010
15.
Fluid-based proteomics targeted on pathophysiological processes and pathologies in neurodegenerative diseases.
J Neurochem
; 151(4): 417-434, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30238462
16.
The intact postsynaptic protein neurogranin is reduced in brain tissue from patients with familial and sporadic Alzheimer's disease.
Acta Neuropathol
; 137(1): 89-102, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30244311
17.
Novel tau fragments in cerebrospinal fluid: relation to tangle pathology and cognitive decline in Alzheimer's disease.
Acta Neuropathol
; 137(2): 279-296, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30547227
18.
Dynamics of extracellular matrix proteins in cerebrospinal fluid and serum and their relation to clinical outcome in human traumatic brain injury.
Clin Chem Lab Med
; 57(10): 1565-1573, 2019 Sep 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-30980710
19.
Trisomy of human chromosome 21 enhances amyloid-ß deposition independently of an extra copy of APP.
Brain
; 141(8): 2457-2474, 2018 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29945247
20.
Elevated CSF GAP-43 is Alzheimer's disease specific and associated with tau and amyloid pathology.
Alzheimers Dement
; 15(1): 55-64, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30321501