[Urologic neoplasms in patients with renal transplantation. Experience and review of the literature]. / Neoplasias urológicas en pacientes con trasplante renal. Experiencia y revisión de la literatura.

The presence of neoplasms in patients with renal transplant in a higher frequency than in general people is known since a long time. The most frequent tumours were the skin tumours, followed by other tumours common in immunosuppressed patients. The ain of this work has been study the frequency, type, diagnosis, treatment and evolution of the urinary system tumours in patients with renal transplant and an exhaustive review of literature. We have found 11 tumours of the urinary system over 57 tumours in 41 patients, with a frequency 26.8%. 6 were kidney tumours, 3 of prostate and 3 of the bladder. We have analyzed the incidence, diagnosis, treatment and evolution of tumour and its effects on the graft. We believe that the posttransplant follow-up of the patient, overcoat in males, who have tumours in more frequency, is important for the early diagnosis.

[Incidence of tumors in renal transplant patients. Is there a changing tumor pattern in these patients?]. / Incidencia de neoplasias en pacientes con trasplante renal. Está cambiando el patrón de neoplasias en estos pacientes?

OBJECTIVE: To analyze the incidence of tumors in renal graft recipients, the course, treatment and its effect on the graft and patient. METHODS: We conducted a retrospective and prospective study on 477 renal transplants performed at our hospital from 1980 to 1996. The tumor type, course and possible tumor-related factors (immunosuppression, age, sex, graft rejection, virus) were analyzed. RESULTS: 57 tumors were found; 41 patients had at least one tumor. The most common were skin, renal and lung cancer. Age, sex and immunosuppression were found to be tumor-related factors in renal transplant recipients. CONCLUSIONS: Patients undergoing renal transplantation are at a higher risk for developing a tumor, above all in the older male patients. A relationship was found for immunosuppression, the number of drugs received and the number of rejection episodes. Furthermore, the tumor pattern in these patients is different from the usual pattern.