Detalhe da pesquisa
1.
Human bronchopulmonary disposition and plasma pharmacokinetics of oral bemnifosbuvir (AT-527), an experimental guanosine nucleotide prodrug for COVID-19.
J Antimicrob Chemother
; 79(6): 1423-1431, 2024 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38708557
2.
Ensovibep, a SARS-CoV-2 antiviral designed ankyrin repeat protein, is safe and well tolerated in healthy volunteers: Results of a first-in-human, ascending single-dose Phase 1 study.
Br J Clin Pharmacol
; 89(7): 2295-2303, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37057679
3.
First-Time-in-Human Study and Prediction of Early Bactericidal Activity for GSK3036656, a Potent Leucyl-tRNA Synthetase Inhibitor for Tuberculosis Treatment.
Antimicrob Agents Chemother
; 63(8)2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31182528
4.
Pharmacokinetics, safety, tolerability and immunogenicity of FKB327, a new biosimilar medicine of adalimumab/Humira, in healthy subjects.
Br J Clin Pharmacol
; 83(7): 1405-1415, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28133772
5.
Long-Term Clinical Safety of the Ad26.ZEBOV and MVA-BN-Filo Ebola Vaccines: A Prospective, Multi-Country, Observational Study.
Vaccines (Basel)
; 12(2)2024 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38400193
6.
A randomized, double-blind, single-dose study (LAVENDER) to assess the safety, tolerability, pharmacokinetics, and immunogenicity of a combined infusion of ABP 980 and pertuzumab in healthy subjects.
Cancer Chemother Pharmacol
; 88(5): 879-886, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34355250
7.
A Phase I Study to Show the Relative Bioavailability and Bioequivalence of Fixed-Dose Combinations of Ambrisentan and Tadalafil in Healthy Subjects.
Clin Ther
; 41(6): 1110-1127, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31060740
8.
Open-Label, Crossover Study to Determine the Pharmacokinetics of Fluticasone Furoate and Batefenterol When Administered Alone, in Combination, or Concurrently.
Clin Pharmacol Drug Dev
; 8(2): 188-197, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30070770
9.
Amenamevir: Studies of Potential CYP2C8- and CYP2B6-Mediated Pharmacokinetic Interactions With Montelukast and Bupropion in Healthy Volunteers.
Clin Pharmacol Drug Dev
; 7(8): 860-870, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29870591
10.
Amenamevir: Studies of Potential CYP3A-Mediated Pharmacokinetic Interactions With Midazolam, Cyclosporine, and Ritonavir in Healthy Volunteers.
Clin Pharmacol Drug Dev
; 7(8): 844-859, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30044899