Detalhe da pesquisa
1.
Nicardipine is a putative EED inhibitor and has high selectivity and potency against chemoresistant prostate cancer in preclinical models.
Br J Cancer
; 129(5): 884-894, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37474721
2.
Constitutively Synergistic Multiagent Drug Formulations Targeting MERTK, FLT3, and BCL-2 for Treatment of AML.
Pharm Res
; 40(9): 2133-2146, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37704893
3.
Small molecule antagonist reveals seizure-induced mediation of neuronal injury by prostaglandin E2 receptor subtype EP2.
Proc Natl Acad Sci U S A
; 109(8): 3149-54, 2012 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-22323596
4.
Reversing chemoresistance by small molecule inhibition of the translation initiation complex eIF4F.
Proc Natl Acad Sci U S A
; 108(3): 1046-51, 2011 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-21191102
5.
Neuroprotection by selective allosteric potentiators of the EP2 prostaglandin receptor.
Proc Natl Acad Sci U S A
; 107(5): 2307-12, 2010 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-20080612
6.
A multiplexed time-resolved fluorescence resonance energy transfer ultrahigh-throughput screening assay for targeting SMAD4-SMAD3-DNA complex.
bioRxiv
; 2023 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37503208
7.
A multiplexed time-resolved fluorescence resonance energy transfer ultrahigh-throughput screening assay for targeting the SMAD4-SMAD3-DNA complex.
J Mol Cell Biol
; 2023 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37968137
8.
TMPRSS2 and SARS-CoV-2 SPIKE interaction assay for uHTS.
J Mol Cell Biol
; 15(3)2023 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36921991
9.
Bromocriptine monotherapy overcomes prostate cancer chemoresistance in preclinical models.
Transl Oncol
; 34: 101707, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37271121
10.
A Novel 7H-[1,2,4]Triazolo[3,4-b]thiadiazine-based Cystic Fibrosis Transmembrane Conductance Regulator Potentiator Directed toward Treatment of Cystic Fibrosis.
ACS Med Chem Lett
; 14(10): 1338-1343, 2023 Oct 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37849531
11.
Constitutively synergistic multiagent drug formulations targeting MERTK, FLT3, and BCL-2 for treatment of AML.
bioRxiv
; 2023 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36993676
12.
Development of constitutively synergistic nanoformulations to enhance chemosensitivity in T-cell leukemia.
J Control Release
; 361: 470-482, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37543290
13.
Sodium pyruvate modulates cell death pathways in HaCaT keratinocytes exposed to half-mustard gas.
Int J Toxicol
; 30(2): 197-206, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21300769
14.
Hypomorph mutation-directed small-molecule protein-protein interaction inducers to restore mutant SMAD4-suppressed TGF-ß signaling.
Cell Chem Biol
; 28(5): 636-647.e5, 2021 05 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33326750
15.
Implementation of a fluorescence-based screening assay identifies histamine H3 receptor antagonists clobenpropit and iodophenpropit as subunit-selective N-methyl-D-aspartate receptor antagonists.
J Pharmacol Exp Ther
; 333(3): 650-62, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20197375
16.
Development of a miniaturized 3D organoid culture platform for ultra-high-throughput screening.
J Mol Cell Biol
; 12(8): 630-643, 2020 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32678871
17.
Cyclosporine A as a Cardioprotective Agent During Donor Heart Retrieval, Storage, or Transportation: Benefits and Limitations.
Transplantation
; 103(6): 1140-1151, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30801551
18.
The influence of N-acetyl-L-cysteine on oxidative stress and nitric oxide synthesis in stimulated macrophages treated with a mustard gas analogue.
BMC Cell Biol
; 9: 33, 2008 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-18570648
19.
Functional recovery after dantrolene-supplementation of cold stored hearts using an ex vivo isolated working rat heart model.
PLoS One
; 13(10): e0205850, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30312353
20.
Development of a Time-Resolved Fluorescence Resonance Energy Transfer Ultrahigh-Throughput Screening Assay for Targeting the NSD3 and MYC Interaction.
Assay Drug Dev Technol
; 16(2): 96-106, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29634317