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Travel Med Infect Dis ; 59: 102714, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38490400

RESUMO

BACKGROUND: Tick- and louse-borne relapsing fever are highly-neglected, vector-borne diseases caused by diverse Borrelia species. Presently, there are no data available on the endemicity of tick- and louse-borne relapsing fever spirochetes in Kenya. Here, we present data of a retrospective study on the seroprevalence of louse-borne relapsing fever (LBRF) in northern Kenya. METHODS: A novel immunoassay, recently established for the diagnosis of LBRF was utilized to screen 2005 blood samples collected from individuals with fever without a source in Turkana County, Kenya between May 2009 and November 2010 for anti-LBRF antibodies. RESULTS: Out of the 2005 sera analyzed, 287 samples (14.3 %) were considered anti-LBRF IgG positive. Subsequent analyses revealed that 87 out of 152 sera randomly selected from these 2005 samples were tested positive (57.2 %) for anti-LBRF IgM antibodies. Most of the IgG and IgM positive samples were from individuals living in northern regions of Turkana County. CONCLUSION: Our serological finding provides strong evidence for the occurrence of LBRF in Kenya.


Assuntos
Anticorpos Antibacterianos , Borrelia , Imunoglobulina G , Imunoglobulina M , Febre Recorrente , Quênia/epidemiologia , Febre Recorrente/epidemiologia , Febre Recorrente/diagnóstico , Febre Recorrente/microbiologia , Febre Recorrente/sangue , Humanos , Estudos Soroepidemiológicos , Estudos Retrospectivos , Masculino , Feminino , Anticorpos Antibacterianos/sangue , Imunoglobulina G/sangue , Borrelia/imunologia , Imunoglobulina M/sangue , Adulto , Animais , Adolescente , Pessoa de Meia-Idade , Adulto Jovem , Criança , Pré-Escolar
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