Detalhe da pesquisa
1.
Human and mouse granzyme A induce a proinflammatory cytokine response.
Immunity
; 29(5): 720-33, 2008 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-18951048
2.
A kinase inhibitor screen reveals protein kinase C-dependent endocytic recycling of ErbB2 in breast cancer cells.
J Biol Chem
; 289(44): 30443-30458, 2014 Oct 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-25225290
3.
Protein tyrosine kinase regulation by ubiquitination: critical roles of Cbl-family ubiquitin ligases.
Biochim Biophys Acta
; 1833(1): 122-39, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23085373
4.
High-throughput compatible fluorescence resonance energy transfer-based assay to identify small molecule inhibitors of AMSH deubiquitinase activity.
Anal Biochem
; 440(1): 71-7, 2013 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23747283
5.
Negative regulation of EGFR-Vav2 signaling axis by Cbl ubiquitin ligase controls EGF receptor-mediated epithelial cell adherens junction dynamics and cell migration.
J Biol Chem
; 286(1): 620-33, 2011 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-20940296
6.
Distinct roles for Rho versus Rac/Cdc42 GTPases downstream of Vav2 in regulating mammary epithelial acinar architecture.
J Biol Chem
; 285(2): 1555-68, 2010 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-19826000
7.
Mechanisms of Trastuzumab resistance in ErbB2-driven breast cancer and newer opportunities to overcome therapy resistance.
J Carcinog
; 10: 28, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-22190870
8.
Continuous requirement of ErbB2 kinase activity for loss of cell polarity and lumen formation in a novel ErbB2/Neu-driven murine cell line model of metastatic breast cancer.
J Carcinog
; 10: 29, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-22190871
9.
CHIP/STUB1 Ubiquitin Ligase Functions as a Negative Regulator of ErbB2 by Promoting Its Early Post-Biosynthesis Degradation.
Cancers (Basel)
; 13(16)2021 Aug 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34439093
10.
Aberrant trafficking of NSCLC-associated EGFR mutants through the endocytic recycling pathway promotes interaction with Src.
BMC Cell Biol
; 10: 84, 2009 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-19948031
11.
Granzyme B activates procaspase-3 which signals a mitochondrial amplification loop for maximal apoptosis.
J Cell Biol
; 160(6): 875-85, 2003 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-12629051
12.
Cytotoxic granule-mediated apoptosis: unraveling the complex mechanism.
Curr Opin Immunol
; 15(5): 528-32, 2003 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-14499261
13.
Marked enhancement of lysosomal targeting and efficacy of ErbB2-targeted drug delivery by HSP90 inhibition.
Oncotarget
; 7(9): 10522-35, 2016 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26859680
14.
Polypeptide-based nanogels co-encapsulating a synergistic combination of doxorubicin with 17-AAG show potent anti-tumor activity in ErbB2-driven breast cancer models.
J Control Release
; 208: 59-66, 2015 Jun 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-25660204
15.
A comprehensive, multi-scale dynamical model of ErbB receptor signal transduction in human mammary epithelial cells.
PLoS One
; 8(4): e61757, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23637902
16.
Mutant Cbl proteins as oncogenic drivers in myeloproliferative disorders.
Oncotarget
; 2(3): 245-50, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21422499
17.
ESCRT proteins: Double-edged regulators of cellular signaling.
Bioarchitecture
; 1(1): 45-48, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21866262
18.
Anticancer activity of Celastrol in combination with ErbB2-targeted therapeutics for treatment of ErbB2-overexpressing breast cancers.
Cancer Biol Ther
; 11(2): 263-76, 2011 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21088503
19.
Induction of cancer cell death by self-assembling nanostructures incorporating a cytotoxic peptide.
Cancer Res
; 70(8): 3020-6, 2010 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20354185
20.
A combination of Trastuzumab and 17-AAG induces enhanced ubiquitinylation and lysosomal pathway-dependent ErbB2 degradation and cytotoxicity in ErbB2-overexpressing breast cancer cells.
Cancer Biol Ther
; 7(10): 1630-40, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18769124