RESUMO
Neurofibromatosis type 1 (NF1) is an inherited disorder often associated with optic nerve gliomas, low-grade brain tumors, and readily visible signs. Though these features are frequently emphasized, the psychosocial and emotional morbidities are often overlooked. We present a patient with depressive disorder resulting in suicide in a patient with NF1.
Assuntos
Astrocitoma/patologia , Transtorno Depressivo/patologia , Neoplasias Hipotalâmicas/patologia , Neurofibromatose 1/patologia , Neoplasias do Nervo Óptico/patologia , Suicídio , Adolescente , Astrocitoma/diagnóstico por imagem , Transtorno Depressivo/diagnóstico , Feminino , Humanos , Neoplasias Hipotalâmicas/diagnóstico por imagem , Imageamento por Ressonância Magnética , Neurofibromatose 1/diagnóstico por imagem , Neoplasias do Nervo Óptico/diagnóstico por imagemRESUMO
The aim of this study is to report a case of bilateral primary mucinous carcinoma of the eyelids. This is a case report and literature review. A 71-year-old female presented with primary mucinous carcinoma of the left upper eyelid, which was excised with Mohs surgery. One year later, she developed primary mucinous carcinoma of the right upper eyelid, which was also treated Mohs surgery. Extensive workup was negative for evidence of an unknown primary carcinoma or metastasis. Primary mucinous carcinoma of the eyelids may occur as multifocal tumors, and bilateral disease is not necessarily indicative of metastatic disease.
Assuntos
Adenocarcinoma Mucinoso/diagnóstico , Neoplasias Palpebrais/diagnóstico , Pálpebras/patologia , Adenocarcinoma Mucinoso/cirurgia , Idoso , Neoplasias Palpebrais/cirurgia , Pálpebras/cirurgia , Feminino , Humanos , Cirurgia de Mohs/métodosRESUMO
A 45-year-old woman with a history of depression and anxiety, treated with selective serotonin reuptake inhibitors (SSRIs), experienced acute, recurrent, and severe bifrontal headaches. Over time, she developed a left homonymous hemianopia and mental status changes. MRA revealed segmental vasoconstriction of cerebral arteries in multiple vascular distributions. She was treated with a calcium-channel blocker and magnesium, and there was resolution of her symptoms and cerebrovascular changes. Her clinical course and neuroimaging findings were consistent with reversible cerebral vasoconstriction syndrome. Although rare, this disorder frequently manifests with visual complaints. Although the prognosis is generally favorable, patients with this syndrome require prompt diagnosis and care directed to avoid complications including stroke, seizure, and subarachnoid hemorrhage.