Detalhe da pesquisa
1.
Cytochrome P450 1A1/2, 2B6 and 3A4 HepaRG Cell-Based Biosensors to Monitor Hepatocyte Differentiation, Drug Metabolism and Toxicity.
Sensors (Basel)
; 19(10)2019 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31096615
2.
Thymoquinone protects rat liver after partial hepatectomy under ischaemia/reperfusion through oxidative stress and endoplasmic reticulum stress prevention.
Clin Exp Pharmacol Physiol
; 2018 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29733120
3.
IL-1ß production is dependent on the activation of purinergic receptors and NLRP3 pathway in human macrophages.
FASEB J
; 29(10): 4162-73, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26116704
4.
Low concentrations of ethylene bisdithiocarbamate pesticides maneb and mancozeb impair manganese and zinc homeostasis to induce oxidative stress and caspase-dependent apoptosis in human hepatocytes.
Chemosphere
; 346: 140535, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37923018
5.
The RNA binding motif protein 15B (RBM15B/OTT3) is a functional competitor of serine-arginine (SR) proteins and antagonizes the positive effect of the CDK11p110-cyclin L2α complex on splicing.
J Biol Chem
; 286(1): 147-59, 2011 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-21044963
6.
Carbon tetrachloride-mediated lipid peroxidation induces early mitochondrial alterations in mouse liver.
Lab Invest
; 92(3): 396-410, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22157718
7.
Differences in early acetaminophen hepatotoxicity between obese ob/ob and db/db mice.
J Pharmacol Exp Ther
; 342(3): 676-87, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22647274
8.
Circumsporozoite Protein of Plasmodium berghei- and George Baker Virus A-Derived Peptides Trigger Efficient Cell Internalization of Bioconjugates and Functionalized Poly(ethylene glycol)-b-poly(benzyl malate)-Based Nanoparticles in Human Hepatoma Cells.
Pharmaceutics
; 14(4)2022 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35456637
9.
In vivo and in vitro α-amanitin metabolism studies using molecular networking.
Toxicol Lett
; 346: 1-6, 2021 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33872745
10.
A therapeutic oxygen carrier isolated from Arenicola marina decreases amanitin-induced hepatotoxicity.
Toxicon
; 200: 87-91, 2021 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-34274377
11.
Synthesis of Poly(Malic Acid) Derivatives End-Functionalized with Peptides and Preparation of Biocompatible Nanoparticles to Target Hepatoma Cells.
Nanomaterials (Basel)
; 11(4)2021 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33918663
12.
Reperfusion stress induced during intermittent selective clamping accelerates rat liver regeneration through JNK pathway.
J Hepatol
; 52(4): 560-9, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20207439
13.
Cyclin-dependent kinase 1 plays a critical role in DNA replication control during rat liver regeneration.
Hepatology
; 50(6): 1946-56, 2009 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19821535
14.
Synthesis of Poly(Dimethylmalic Acid) Homo- and Copolymers to Produce Biodegradable Nanoparticles for Drug Delivery: Cell Uptake and Biocompatibility Evaluation in Human Heparg Hepatoma Cells.
Polymers (Basel)
; 12(8)2020 Jul 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-32751402
15.
Cell Uptake and Biocompatibility of Nanoparticles Prepared from Poly(benzyl malate) (Co)polymers Obtained through Chemical and Enzymatic Polymerization in Human HepaRG Cells and Primary Macrophages.
Polymers (Basel)
; 10(11)2018 Nov 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30961169
16.
Thymoquinone prevents endoplasmic reticulum stress and mitochondria-induced apoptosis in a rat model of partial hepatic warm ischemia reperfusion.
Biomed Pharmacother
; 94: 964-973, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28810534
17.
Opsonisation of nanoparticles prepared from poly(ß-hydroxybutyrate) and poly(trimethylene carbonate)-b-poly(malic acid) amphiphilic diblock copolymers: Impact on the in vitro cell uptake by primary human macrophages and HepaRG hepatoma cells.
Int J Pharm
; 513(1-2): 438-452, 2016 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27640247
18.
Pretreatment with mangafodipir improves liver graft tolerance to ischemia/reperfusion injury in rat.
PLoS One
; 7(11): e50235, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23226251
19.
Combined Stimulation with the Tumor Necrosis Factor α and the Epidermal Growth Factor Promotes the Proliferation of Hepatocytes in Rat Liver Cultured Slices.
Int J Hepatol
; 2012: 785786, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23119170
20.
Highly efficient gene transfer into hepatocyte-like HepaRG cells: new means for drug metabolism and toxicity studies.
Biotechnol J
; 5(3): 314-20, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-20213646