Detalhe da pesquisa
1.
Doublecortin-like Kinase 1 Regulates α-Synuclein Levels and Toxicity.
J Neurosci
; 40(2): 459-477, 2020 01 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31748376
2.
An autism-linked missense mutation in SHANK3 reveals the modularity of Shank3 function.
Mol Psychiatry
; 25(10): 2534-2555, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30610205
3.
RAS-MAPK-MSK1 pathway modulates ataxin 1 protein levels and toxicity in SCA1.
Nature
; 498(7454): 325-331, 2013 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-23719381
4.
Fragile X-like behaviors and abnormal cortical dendritic spines in cytoplasmic FMR1-interacting protein 2-mutant mice.
Hum Mol Genet
; 24(7): 1813-23, 2015 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25432536
5.
Duplication of Atxn1l suppresses SCA1 neuropathology by decreasing incorporation of polyglutamine-expanded ataxin-1 into native complexes.
Nat Genet
; 39(3): 373-9, 2007 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-17322884
6.
Polyglutamine disease toxicity is regulated by Nemo-like kinase in spinocerebellar ataxia type 1.
J Neurosci
; 33(22): 9328-36, 2013 May 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-23719801
7.
Opposing effects of polyglutamine expansion on native protein complexes contribute to SCA1.
Nature
; 452(7188): 713-8, 2008 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-18337722
8.
Regional rescue of spinocerebellar ataxia type 1 phenotypes by 14-3-3epsilon haploinsufficiency in mice underscores complex pathogenicity in neurodegeneration.
Proc Natl Acad Sci U S A
; 108(5): 2142-7, 2011 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21245341
9.
Cross-species genetic screens identify transglutaminase 5 as a regulator of polyglutamine-expanded ataxin-1.
J Clin Invest
; 132(9)2022 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35499073
10.
Ronin overexpression induces cerebellar degeneration in a mouse model of ataxia.
Dis Model Mech
; 14(6)2021 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34165550
11.
Autism and other neuropsychiatric symptoms are prevalent in individuals with MeCP2 duplication syndrome.
Ann Neurol
; 66(6): 771-82, 2009 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-20035514
12.
RBM17 Interacts with U2SURP and CHERP to Regulate Expression and Splicing of RNA-Processing Proteins.
Cell Rep
; 25(3): 726-736.e7, 2018 10 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30332651
13.
Lithium therapy improves neurological function and hippocampal dendritic arborization in a spinocerebellar ataxia type 1 mouse model.
PLoS Med
; 4(5): e182, 2007 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-17535104
14.
Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans.
Nat Genet
; 49(4): 527-536, 2017 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-28288114
15.
Ataxin-1 oligomers induce local spread of pathology and decreasing them by passive immunization slows Spinocerebellar ataxia type 1 phenotypes.
Elife
; 42015 Dec 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-26673892
16.
A native interactor scaffolds and stabilizes toxic ATAXIN-1 oligomers in SCA1.
Elife
; 42015 May 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25988806
17.
ATAXIN-1 interacts with the repressor Capicua in its native complex to cause SCA1 neuropathology.
Cell
; 127(7): 1335-47, 2006 Dec 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-17190598
18.
The effects of histones H1o, H5 and HMG proteins on cell division of cultured murine erythroleukemia cells.
Wilehm Roux Arch Dev Biol
; 194(1): 53-55, 1984 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-28305194
19.
Mild overexpression of MeCP2 causes a progressive neurological disorder in mice.
Hum Mol Genet
; 13(21): 2679-89, 2004 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15351775