Detalhe da pesquisa
1.
Systematic comparison of family history and polygenic risk across 24 common diseases.
Am J Hum Genet
; 109(12): 2152-2162, 2022 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36347255
2.
Integrating transcriptomics, metabolomics, and GWAS helps reveal molecular mechanisms for metabolite levels and disease risk.
Am J Hum Genet
; 109(10): 1727-1741, 2022 10 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36055244
3.
Author Correction: Exome sequencing of Finnish isolates enhances rare-variant association power.
Nature
; 575(7783): E4, 2019 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-31686056
4.
Exome sequencing of Finnish isolates enhances rare-variant association power.
Nature
; 572(7769): 323-328, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31367044
5.
Imputation of missing values in lipidomic datasets.
Proteomics
; : e2300606, 2024 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38602226
6.
High-Resolution Genotyping of Formalin-Fixed Tissue Accurately Estimates Polygenic Risk Scores in Human Diseases.
Lab Invest
; 104(4): 100325, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38220043
7.
Genome-wide polygenic risk scores for colorectal cancer have implications for risk-based screening.
Br J Cancer
; 130(4): 651-659, 2024 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38172535
8.
Association of structural variation with cardiometabolic traits in Finns.
Am J Hum Genet
; 108(4): 583-596, 2021 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33798444
9.
Patterns of reproductive health in inflammatory rheumatic diseases and other immune-mediated diseases: a nationwide registry study.
Rheumatology (Oxford)
; 2024 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38503536
10.
ANGPTL8 protein-truncating variant associated with lower serum triglycerides and risk of coronary disease.
PLoS Genet
; 17(4): e1009501, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33909604
11.
Changes in the fine-scale genetic structure of Finland through the 20th century.
PLoS Genet
; 17(3): e1009347, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33661898
12.
Exploring machine learning strategies for predicting cardiovascular disease risk factors from multi-omic data.
BMC Med Inform Decis Mak
; 24(1): 116, 2024 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38698395
13.
Longitudinal multi-omics study reveals common etiology underlying association between plasma proteome and BMI trajectories in adolescent and young adult twins.
BMC Med
; 21(1): 508, 2023 12 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38129841
14.
Polygenic scores in biomedical research.
Nat Rev Genet
; 23(9): 524-532, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35354965
15.
Geographic Variation and Bias in the Polygenic Scores of Complex Diseases and Traits in Finland.
Am J Hum Genet
; 104(6): 1169-1181, 2019 06 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31155286
16.
Multivariate Genome-wide Association Analysis of a Cytokine Network Reveals Variants with Widespread Immune, Haematological, and Cardiometabolic Pleiotropy.
Am J Hum Genet
; 105(6): 1076-1090, 2019 12 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31679650
17.
Effects of PNPLA3 I148M on hepatic lipid and very-low-density lipoprotein metabolism in humans.
J Intern Med
; 291(2): 218-223, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34411351
18.
Mitochondrial genome copy number measured by DNA sequencing in human blood is strongly associated with metabolic traits via cell-type composition differences.
Hum Genomics
; 15(1): 34, 2021 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34099068
19.
Genome-wide association meta-analysis of nicotine metabolism and cigarette consumption measures in smokers of European descent.
Mol Psychiatry
; 26(6): 2212-2223, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32157176
20.
Polygenic burden has broader impact on health, cognition, and socioeconomic outcomes than most rare and high-risk copy number variants.
Mol Psychiatry
; 26(9): 4884-4895, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33526825