Detalhe da pesquisa
1.
Telomere-to-telomere assembly of a complete human X chromosome.
Nature
; 585(7823): 79-84, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32663838
2.
Ultra-deep mutational landscape in chronic lymphocytic leukemia uncovers dynamics of resistance to targeted therapies.
Haematologica
; 109(3): 835-845, 2024 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37706363
3.
PolyG-DS: An ultrasensitive polyguanine tract-profiling method to detect clonal expansions and trace cell lineage.
Proc Natl Acad Sci U S A
; 118(31)2021 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34330826
4.
Targeted genome fragmentation with CRISPR/Cas9 enables fast and efficient enrichment of small genomic regions and ultra-accurate sequencing with low DNA input (CRISPR-DS).
Genome Res
; 28(10): 1589-1599, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30232196
5.
Characterizing TP53 mutations in ovarian carcinomas with and without concurrent BRCA1 or BRCA2 mutations.
Gynecol Oncol
; 160(3): 786-792, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33375991
6.
Aging and the rise of somatic cancer-associated mutations in normal tissues.
PLoS Genet
; 14(1): e1007108, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29300727
7.
Characterization of TP53 mutations in Pap test DNA of women with and without serous ovarian carcinoma.
Gynecol Oncol
; 156(2): 407-414, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31839337
8.
Ultra-deep sequencing detects ovarian cancer cells in peritoneal fluid and reveals somatic TP53 mutations in noncancerous tissues.
Proc Natl Acad Sci U S A
; 113(21): 6005-10, 2016 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-27152024
9.
Seshat: A Web service for accurate annotation, validation, and analysis of TP53 variants generated by conventional and next-generation sequencing.
Hum Mutat
; 39(7): 925-933, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29696732
10.
Precancer in ulcerative colitis: the role of the field effect and its clinical implications.
Carcinogenesis
; 39(1): 11-20, 2018 01 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29087436
11.
Genetic clonal diversity predicts progression to esophageal adenocarcinoma.
Nat Genet
; 38(4): 468-73, 2006 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-16565718
12.
Clonal expansions in ulcerative colitis identify patients with neoplasia.
Proc Natl Acad Sci U S A
; 106(49): 20871-6, 2009 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-19926851
13.
Colorectal Cancer Is Associated with the Presence of Cancer Driver Mutations in Normal Colon.
Cancer Res
; 82(8): 1492-1502, 2022 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35425963
14.
Antiprogestins reduce epigenetic field cancerization in breast tissue of young healthy women.
Genome Med
; 14(1): 64, 2022 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35701800
15.
Uterine lavage identifies cancer mutations and increased TP53 somatic mutation burden in individuals with ovarian cancer.
Cancer Res Commun
; 2(10): 1282-1292, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36311816
16.
Assessment of gene expression in many samples using vertical arrays.
Nucleic Acids Res
; 36(10): e60, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18474526
17.
Ulcerative colitis is a disease of accelerated colon aging: evidence from telomere attrition and DNA damage.
Gastroenterology
; 135(2): 410-8, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18519043
18.
Cancer-Associated Mutations but No Cancer: Insights into the Early Steps of Carcinogenesis and Implications for Early Cancer Detection.
Trends Cancer
; 5(9): 531-540, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31474358
19.
Mitochondrial DNA Mutations are Associated with Ulcerative Colitis Preneoplasia but Tend to be Negatively Selected in Cancer.
Mol Cancer Res
; 17(2): 488-498, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30446624
20.
Ultra-Sensitive TP53 Sequencing for Cancer Detection Reveals Progressive Clonal Selection in Normal Tissue over a Century of Human Lifespan.
Cell Rep
; 28(1): 132-144.e3, 2019 07 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31269435