Detalhe da pesquisa
1.
Center of Biomedical Research Excellence in Matrix Biology: Building Research Infrastructure, Supporting Young Researchers, and Fostering Collaboration.
Int J Mol Sci
; 21(6)2020 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32244989
2.
Intranasal delivery of shRNA to knockdown the 5HT-2A receptor enhances memory and alleviates anxiety.
Transl Psychiatry
; 14(1): 154, 2024 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38509093
3.
Proteolytic cleavage of apolipoprotein E4 as the keystone for the heightened risk associated with Alzheimer's disease.
Int J Mol Sci
; 14(7): 14908-22, 2013 Jul 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-23867607
4.
Genetic modulation of the HTR2A gene reduces anxiety-related behavior in mice.
PNAS Nexus
; 2(6): pgad170, 2023 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-37346271
5.
An amino-terminal fragment of apolipoprotein E4 leads to behavioral deficits, increased PHF-1 immunoreactivity, and mortality in zebrafish.
PLoS One
; 17(12): e0271707, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36520946
6.
Depletion of Beclin-1 due to proteolytic cleavage by caspases in the Alzheimer's disease brain.
Neurobiol Dis
; 43(1): 68-78, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21081164
7.
Fragmentation of Apolipoprotein E4 is Required for Differential Expression of Inflammation and Activation Related Genes in Microglia Cells.
Int J Neurodegener Dis
; 4(1)2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34693295
8.
The role of caspases in Alzheimer's disease; potential novel therapeutic opportunities.
Apoptosis
; 15(11): 1403-9, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20127416
9.
Caspase-cleaved transactivation response DNA-binding protein 43 in Parkinson's disease and dementia with Lewy bodies.
Neurodegener Dis
; 7(4): 243-50, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20551689
10.
Clinical Trials in Alzheimer's Disease: A Hurdle in the Path of Remedy.
Int J Alzheimers Dis
; 2020: 5380346, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32308993
11.
Transcriptome Analyses in BV2 Microglial Cells Following Treatment With Amino-Terminal Fragments of Apolipoprotein E.
Front Aging Neurosci
; 12: 256, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32922284
12.
Lack of pathology in a triple transgenic mouse model of Alzheimer's disease after overexpression of the anti-apoptotic protein Bcl-2.
J Neurosci
; 28(12): 3051-9, 2008 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-18354008
13.
A Fragment of Apolipoprotein E4 Leads to the Downregulation of a CXorf56 Homologue, a Novel ER-Associated Protein, and Activation of BV2 Microglial Cells.
Oxid Med Cell Longev
; 2019: 5123565, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31198491
14.
Caspase activation in Alzheimer's disease: early to rise and late to bed.
Rev Neurosci
; 19(6): 383-93, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-19317178
15.
Caspase-cleaved TAR DNA-binding protein-43 is a major pathological finding in Alzheimer's disease.
Brain Res
; 1228: 189-98, 2008 Sep 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-18634762
16.
Apolipoprotein E Fragmentation within Lewy Bodies of the Human Parkinson's Disease Brain.
Int J Neurodegener Dis
; 1(1)2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30272057
17.
The Potential of CRISPR/Cas9 Gene Editing as a Treatment Strategy for Alzheimer's Disease.
J Alzheimers Dis Parkinsonism
; 8(3)2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30090689
18.
Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology.
J Clin Invest
; 114(1): 121-30, 2004 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-15232619
19.
Nuclear Localization of Apolipoprotein E4: A New Trick for an Old Protein.
Int J Neurol Neurother
; 4(2)2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29264400
20.
Nuclear uptake of an amino-terminal fragment of apolipoprotein E4 promotes cell death and localizes within microglia of the Alzheimer's disease brain.
Int J Physiol Pathophysiol Pharmacol
; 9(2): 40-57, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28533891