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1.
Medicina (Kaunas) ; 60(2)2024 Jan 30.
Artigo em Inglês | MEDLINE | ID: mdl-38399527

RESUMO

Background and Objectives: Surgical guides might impede the flow of coolant to the implant drills during the preparation of the implant bed, potentially contributing to increased temperatures during bone drilling. The objective of this experimental study was to assess the cooling efficiency of various guiding cylinder designs for sleeveless surgical guides used in guided surgery. Materials and Methods: In this experimental study, surgical guides with three different guiding cylinder designs were printed. One group had solid cylinders (control) and two test groups (cylinders with pores and cylinders with windows). Forty customized polyurethane blocks with type III bone characteristics were fitted into the guide and fixed in a vise, and implant bed preparations were completed using a simplified drilling protocol with and without irrigation. An infrared thermographic camera was used to record the temperature changes during drilling at the coronal, middle, and apical areas. ANOVA test and Games-Howell post hoc test were used to determine significant thermal differences among groups. Results: A significant thermal increase was observed at the coronal area in the group without irrigation (39.69 ± 8.82) (p < 0.05). The lowest thermal increase was recorded at the surgical guides with windows (21.451 ± 0.703 °C) compared to solid (25.005 ± 0.586 °C) and porous surgical guides (25.630 ± 1.004) (p < 0.05). In the middle and apical areas, there were no differences between solid and porous cylinders (p > 0.05). Conclusions: 3D-printed sleeveless surgical guides with window openings at the guiding cylinders reduce the temperature elevation at the cortical bone in guided implant surgery.


Assuntos
Osteotomia , Próteses e Implantes , Humanos , Osso Cortical , Microcirurgia , Impressão Tridimensional
2.
Clin Oral Investig ; 27(12): 7841-7849, 2023 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-38010423

RESUMO

OBJECTIVES: Different approaches to prosthodontic consultation, all involving a strong focus on shared decision-making, were analyzed from the perspective of patients by inter-group comparisons. No patient decision aid (PDA) was used in the control group, a paper-based PDA in test group 1, and a software-based PDA in test group 2. MATERIALS AND METHODS: Seventy-five patients were prospectively randomized to the control group or a test group. All patients then rated the consultation on a questionnaire, six key items of which were analyzed, along with the time spent on each consultation. RESULTS: Overall satisfaction was highest in test group 2, with a significant difference from the control group (p = 0.015). Test group 2 showed the most favorable ratings for all six questionnaire items, which invariably was significant compared to the control group (p = 0.032). Test group 1 significantly differed from test group 2 based on two items (consultation was adequately intelligible: p = 0.011; consultation was adequately comprehensive: p = 0.034) but not from the control group based on any item (p = 0.070). CONCLUSIONS: Within the limitations of this study, the use of a software-based PDA, in particular, can be recommended based on patient satisfaction and was associated with the shortest sessions for consultation. CLINICAL RELEVANCE: Patients are routinely faced with a wealth of information in dental offices and may be overwhelmed especially by prosthetic treatment options and decision requirements. Our findings shed some light on the nature of aids that may truly be helpful in the process of shared decision-making. TRIAL REGISTRATION: ClinicalTrials.gov.Identifier: ISRCTN11472465.


Assuntos
Participação do Paciente , Prostodontia , Humanos , Estudos Prospectivos , Encaminhamento e Consulta , Técnicas de Apoio para a Decisão , Tomada de Decisões
3.
J Prosthet Dent ; 129(4): 527-530, 2023 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-34389152

RESUMO

A straightforward, laser-assisted method of extracting the metal housings from an overdenture by using the visible (blue) light of a high-power dental diode laser is presented. This approach produced localized softening of the acrylic resin, allowing the metal housing to be dislodged without damage. This technique minimizes damage to the metal housings during removal, is rapid and conservative, and may help reduce patient costs.


Assuntos
Revestimento de Dentadura , Lasers Semicondutores , Humanos , Lasers Semicondutores/uso terapêutico , Metais , Resinas Acrílicas
4.
J Oral Implantol ; 49(4): 428-435, 2023 Aug 01.
Artigo em Inglês | MEDLINE | ID: mdl-37527148

RESUMO

The placement of implants in the anterior maxillary and mandibular region requires esthetic proficiency and surgical finesse. It is important to consider the esthetic outcome while avoiding any type of nerve injury for the patient. In this literature review, anatomical structures of the anterior jaw were reviewed from a gross anatomical and radiographic interpretation. A discussion on the frequency of neurosensory complications for patients as a result of nerve damage in this region was evaluated. The purpose of this literature review was to educate the dental surgeon to consider the anterior jaw's neurological structures when performing procedures like implant surgery. The mandibular incisive canal (MIC) presents as an extension of the inferior alveolar canal that runs between the mental foramina. The MIC is a structure that is easily depicted in cone-beam computed tomography (CBCT) imaging and is present in most subjects in gross anatomical studies. The anterior loop of the mental nerve is another structure that is discussed in this paper. Although its structure is accurately depicted in CBCT images, its anatomical variations in patients can make implant treatment planning difficult. The maxilla contains 2 neurovascular structures that were discussed. First, the nasopalatine canal and its relation and impact on implant placement is evaluated. Case reports are reviewed that outline a prophylactic enucleation and bone grafting of the canal prior to implant placement. Second, the canalis sinuosus, which houses the anterior superior alveolar nerve, is of concern during implant placement in the lateral incisor region. Case reports involving nerve damage with follow-up are discussed.


Assuntos
Implantes Dentários , Humanos , Maxila/diagnóstico por imagem , Maxila/cirurgia , Estética Dentária , Mandíbula/diagnóstico por imagem , Mandíbula/cirurgia , Tomografia Computadorizada de Feixe Cônico
5.
J Oral Implantol ; 49(4): 401-406, 2023 Aug 01.
Artigo em Inglês | MEDLINE | ID: mdl-37527174

RESUMO

This study aimed to evaluate temperature changes in titanium and ceramic implants after using a 445-nm diode laser under different in vitro conditions. Titanium (Ti) and ceramic (Zr) dental implants were placed into a bone analog, and an intrabony defect was created at each implant. A 445-nm diode laser was used to irradiate the defects for 30 seconds, noncontact, at 2 W in continuous wave (c.w.) and pulsed mode. The experiment was done at room temperature (21.0 ± 1°C) and in a water bath (37.0 ± 1°C). Two thermocouple probes were used to record real-time temperature changes (°C) at the coronal part of the implant (Tc) and the apex (Ta). The temperature was recorded at time 0 (To) and after 30 seconds of irradiation (Tf). The average temperature change was calculated, and a descriptive analysis was conducted (P < .05). The Ti implant resulted in the highest ΔT values coronally (29.6°C) and apically (6.7°C) using continuous wave at 21°C. The Zr implant increased to 26.4°C coronally and 5.2°C apically. In the water bath, the coronal portion of the Ti and Zr implants rose to 14.2°C and 14.01°C, respectively, using continuous waves. The ΔT values for Ti were 11.9°C coronally and 1.7°C apically when placed in a water bath using pulsed mode. The lowest ΔT occurred on the Zr implant with ΔTc and ΔTa of 4.8°C and 0.78°C, respectively. Under in vitro conditions, the 445-nm diode laser in pulsed mode seems to be safe for use on ceramic implants and should be used with caution on titanium implants.


Assuntos
Implantes Dentários , Lasers Semicondutores , Titânio , Temperatura , Água
6.
J Prosthodont ; 2023 Aug 15.
Artigo em Inglês | MEDLINE | ID: mdl-37581292

RESUMO

PURPOSE: To evaluate the accuracy of three torque-control devices used on healing abutments in implant prosthodontics. MATERIALS AND METHODS: In this in vitro experiment, three torque controllers, Ankylos friction-based, Straumann spring-based, and Anthogyr pre-calibrated torque control devices were used to tighten the healing abutments of Ankylos and Straumann dental implants to a pre-determined value of 15 Ncm. A digital torque meter (DT), Cedar DID-4A, was used to assess removal torque as a surrogate for the accuracy of the torque controllers to apply a tightening force of 15 Ncm on healing abutments.  One-way analysis of variance (ANOVA) was used to identify differences between each torque controller and the digital torquemeter, a p < 0.05 was considered significant. RESULTS: The torque required to remove the healing abutments was 16.05 ± 0.66 Ncm for the Ankylos ratchet, 12.61 ± 0.90 Ncm for the Straumann ratchet, and 14.37 ± 1.08 Ncm for the Anthogyr torque-control device. Significant statistical differences were observed between Ankylos and the control digital torquemeter (p = 1.84E-8 ; F = 50.3); Anthogyr and control digital torquemeter (p = 0.01; F = 6.79); and Straumann and control digital torquemeter (p = 0.01; F = 141.15). CONCLUSION: Friction-based (Ankylos), spring-based (Straumann), and pre-calibrated (Anthogyr) torque control devices present over-torque and under-torque values when used over healing abutments of Ankylos and Straumann implant systems.

7.
Periodontol 2000 ; 88(1): 52-63, 2022 02.
Artigo em Inglês | MEDLINE | ID: mdl-35103318

RESUMO

Implant site preparation is a critical stage of implant surgery that may underpin various complications related to implant surgery. This review discusses the latest available scientific information on risk factors related to implant site preparation. The role of the drilling process in relation to the density of the available alveolar bone, the effects of insertion torque on peri-implant osseous healing, and implant-related variables such as macrodesign and implant-abutment connection are all factors that can influence implant success. Novel information that links osteotomy characteristics (including methods to improve implant initial stability, the impact of drilling speed, and increase of the implant insertion torque modifying the bone-implant interface) with the appropriate instrumentation techniques will be discussed, as well as interactions at the bone-biomaterial interface that may lead to biologic complications mediated by implant dissolution products.


Assuntos
Implantação Dentária Endóssea , Implantes Dentários , Interface Osso-Implante , Implantação Dentária Endóssea/métodos , Implantes Dentários/efeitos adversos , Humanos , Osteotomia/métodos , Torque
8.
Periodontol 2000 ; 90(1): 236-246, 2022 10.
Artigo em Inglês | MEDLINE | ID: mdl-35916776

RESUMO

Every year more and more innovative pharmacological agents are introduced medicine, to treat systemic diseases. Due to these rapid and recent advancements, many patients are receiving treatment with a high variety of drugs, such as selective serotonin reuptake inhibitors, bisphosphonates, tumor necrosis factor (TNF)-α inhibitors, cyclosporine, and steroids. Since implant and osseous surgery are common treatment modalities used, within dentistry, it is of critical important to acknowledge and discuss the potential effects of selective serotonin reuptake inhibitors, bisphosphonates, TNF-α inhibitors, cyclosporine, and steroids, on bone healing. The present paper discusses the possible detrimental ramifications and risks these drug classes may have on bone healing.


Assuntos
Reabsorção Óssea , Ciclosporinas , Implantes Dentários , Reabsorção Óssea/induzido quimicamente , Implantes Dentários/efeitos adversos , Difosfonatos/efeitos adversos , Humanos , Inibidores Seletivos de Recaptação de Serotonina/efeitos adversos , Fator de Necrose Tumoral alfa
9.
Periodontol 2000 ; 88(1): 64-72, 2022 02.
Artigo em Inglês | MEDLINE | ID: mdl-35103317

RESUMO

Clinical considerations and treatment criteria in implant placement are constantly evolving. Prosthetically driven implant surgery has become the standard of care to improve short and long-term functional and esthetic outcomes. Therefore, implant position and angulation are planned according to the available bone, anatomical structures, and the requirements of the future prosthetic superstructure. In parallel with these developments, significant progress has been made in data imaging and different software technologies to allow the integration of data within a digital file format. Digitalization in implant surgery enables optimal planning of implant position, as well as the ability to transfer this planning to the surgical field-a process defined as "computer-supported implant planning and guided surgery." The aims of the present review are as follows: (a) to critically appraise the indications and potential "added value" of guided implant surgery, elaborating the main differences between dynamic and static guidance; and (b) to discuss the most important clinical considerations relevant for the different steps of the workflow that might influence the surgical outcome and to offer recommendations on how to avoid or reduce process errors in order to optimize treatment outcomes.


Assuntos
Implantes Dentários , Cirurgia Assistida por Computador , Desenho Assistido por Computador , Implantação Dentária Endóssea/métodos , Humanos , Cirurgia Assistida por Computador/métodos , Resultado do Tratamento , Fluxo de Trabalho
10.
Clin Oral Investig ; 26(3): 2879-2886, 2022 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-34767097

RESUMO

OBJECTIVES: There is no information today about the impact of abutment type on the crestal bone stability. This retrospective study was aimed to evaluate the crestal bone levels (CBL) and failures of implants with prefabricated and customized abutments after the long term. MATERIALS AND METHODS: The mesial and distal CBL around dental implants with prefabricated and custom abutments were recorded. Measures were completed at 5- and 10-year endpoints. RESULTS: Sixty-three patients with 249 implants were included. One hundred twenty-seven implants (51%) were restored with prefabricated and 122 implants (49%) with customized abutments. All the patients received fixed restorations. The results showed that the CBL was higher in patients with custom abutments than the CBL of patients with prefabricated abutments. The mean bone loss around implants with prefabricated abutments was 0.29 mm mesial/0.45 mm distal after 10 years. Meanwhile, the mean bone loss at implants with custom abutments was 1.19 mm mesial/1.27 mm distal (p < 0.05) after 10 years. None of the implants with prefabricated abutments failed up to 10-year follow-up, whereas 4.1% of implants with customized abutments failed. CONCLUSION: Implants with prefabricated abutments present less crestal bone loss compared to customized abutments. CLINICAL RELEVANCE: The selection of abutment type is associated with the crestal bone stability or marginal bone loss.


Assuntos
Perda do Osso Alveolar , Implantes Dentários , Perda do Osso Alveolar/diagnóstico por imagem , Dente Suporte , Implantação Dentária Endóssea/métodos , Prótese Dentária Fixada por Implante , Seguimentos , Humanos , Estudos Retrospectivos
11.
Medicina (Kaunas) ; 58(10)2022 Sep 28.
Artigo em Inglês | MEDLINE | ID: mdl-36295525

RESUMO

This study aims to evaluate the grid of Merz and ImageJ methods for histometric quantification, verifying which is more reliable and defining which is most suitable based on the time required to perform. Thirty histological samples of maxillary sinuses grafted with xenografts were evaluated using an optical light microscope attached to an image capture camera and connected to a microcomputer. The images were digitalized and recorded as a TIFF image, and the new bone formation was evaluated using the grid of Merz and ImageJ. The Bland-Altman analysis was used to identify the agreement between the methods and determine suitable future research options. The timing of the quantification was also performed to identify a possible advantage. The mean value for the quantification analysis timing for the grid of Merz was 194.9 ± 72.0 s and for ImageJ was 871.7 ± 264.4, with statistical significance between the groups (p = 0.0001). The Bland-Altman analysis demonstrated a concordance between the methods, due to the bias being next to the maximum concordance (-1.25) in addition to the graphic showing the scattering points next to the mean of differences and inside of limits of agreement. Thus, it was demonstrated that the grid of Merz presents reliable outcomes and advantages over the ImageJ methodology regarding the time spent to contour the areas of interest.


Assuntos
Osso e Ossos , Humanos , Viés
12.
Clin Oral Investig ; 25(9): 5351-5361, 2021 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-33624200

RESUMO

OBJECTIVE: To evaluate the efficiency of depigmentation, patient perceptions, and the recurrence rates of physiological gingival pigments during a 2-year follow-up after ablative depigmentation using two laser wavelengths: diode 940 nm and Er,Cr:YSGG 2780 nm. MATERIALS AND METHODS: Sixty patients exhibiting physiological melanin hyperpigmentation in the buccal maxillary gingiva were randomly divided into two equal groups treated with an Er,Cr:YSGG laser at 2780 nm, and a 940 nm diode laser, respectively. The depigmentation procedure essentially involves the ablation of epithelial tissue exhibiting melanin pigmentation. The intensity and extensity indices of gingival pigments were evaluated at baseline, 1 month, 1 year, and 2 years. RESULTS: At all time points following depigmentation treatment, oral pigmentation index (OPI) and melanin pigmentation index (MPI) scores were less significantly (p <0.05) compared to the baseline in both groups. Treatment was significantly faster with Er,Cr:YSGG laser and required no anesthesia, with faster healing and less postoperative discomfort after 1-week of treatment, compared to the diode laser treatment (p <0.001). The re-pigmentation intensity and extensity were higher significantly in the Er,Cr:YSGG group than in the diode group at 1 year and 2 years (p <0.05). CONCLUSION: Both lasers efficiently removed gingival pigments with comparable clinical outcomes and overall positive patient experience. Diode laser treatment exhibited better long-term stability of gingival color, with a lower incidence of re-pigmentation. CLINICAL RELEVANCE: The color of the gingiva plays an important role in the esthetics of oral soft tissues and the overall ideal smile. Laser-assisted gingival depigmentation is an effective, comfortable, and reliable technique with good esthetical outcomes. The rate of re-pigmentation was affected by the laser wavelength and the technique used.


Assuntos
Terapia a Laser , Lasers de Estado Sólido , Estética Dentária , Gengiva/cirurgia , Humanos , Lasers de Estado Sólido/uso terapêutico , Percepção , Pigmentação
13.
Clin Oral Investig ; 25(7): 4349-4357, 2021 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-33389135

RESUMO

OBJECTIVES: The purpose of this study was to compare the anti-inflammatory efficacy of sodium chloride- and a 0.12% chlorhexidine mouth rinses in patients undergoing minimal invasive periodontal surgery. MATERIALS AND METHODS: Forty-seven patients with a diagnosis of periodontitis and indication for access flap procedure were randomly selected. Group A: a sodium chloride (salt)water-based mouth rinse (test group) or group B: a 0.12% chlorhexidine mouth rinse (control group) administered after surgery. Gingival Index (GI) were evaluated in the whole mouth and in the surgical site at baseline (T1), a week later (T2), and 12 weeks (T3) after the treatment. Total MMP activity was measured in GCF using a commercial kit and plate reader. Medians of total MMP activity and GI were compared for time intervals T1 vs. T2, T1 vs. T3, and T2 vs T3 using Friedman tests and Wilcoxon signed rank tests, and were also compared between test and control using Mann-WhitneyU tests at each timepoint. RESULTS: The average GI values showed significant differences between baseline and T2 (p = 0.0005) and baseline and T3 (p = 0.003) in the test group. CONCLUSION: The sodium chloride-mouth rinse use after periodontal surgery seems to have similar anti-inflammatory properties as CHX mouth rinse and can be used regularly postoperatively after periodontal surgical procedures. CLINICAL RELEVANCE: The use of salt water mouthwash showed an anti-inflammatory effect similar to CHX 0.12% after minimal invasive periodontal surgery. Salt water mouthwash is accessible to the world population and can contribute on the healing process after periodontal surgery.


Assuntos
Anti-Infecciosos Locais , Placa Dentária , Clorexidina , Índice de Placa Dentária , Método Duplo-Cego , Humanos , Antissépticos Bucais , Estudos Prospectivos , Água
14.
Int J Mol Sci ; 22(3)2021 Jan 21.
Artigo em Inglês | MEDLINE | ID: mdl-33494539

RESUMO

The objective of this review was to analyze the process of wear of implants leading to the shedding of titanium particles into the peri-implant hard and soft tissues. Titanium is considered highly biocompatible with low corrosion and toxicity, but recent studies indicate that this understanding may be misleading as the properties of the material change drastically when titanium nanoparticles (NPs) are shed from implant surfaces. These NPs are immunogenic and are associated with a macrophage-mediated inflammatory response by the host. The literature discussed in this review indicates that titanium NPs may be shed from implant surfaces at the time of implant placement, under loading conditions, and during implant maintenance procedures. We also discuss the significance of the micro-gap at the implant-abutment interface and the effect of size of the titanium particles on their toxicology. These findings are significant as the titanium particles can have adverse effects on local soft and hard tissues surrounding implants, implant health and prognosis, and even the health of systemic tissues and organs.


Assuntos
Implantes Dentários , Titânio , Desgaste dos Dentes , Força de Mordida , Implantação Dentária/instrumentação , Implantação Dentária/métodos , Humanos , Nanopartículas Metálicas , Fatores de Tempo , Dente Artificial
15.
Medicina (Kaunas) ; 57(9)2021 Sep 06.
Artigo em Inglês | MEDLINE | ID: mdl-34577863

RESUMO

Background and Objectives: To evaluate the condensation and the microarchitecture of implant bed walls of sites prepared with counterclockwise drilling with tapered implant drills using optical coherence tomography. Materials and Methods: Four drill designs with different wall and tip angles were used. Polyurethane laminas resembling type IV bone microarchitecture were superimposed and clamped with a vice to simulate the coronal, middle, and apical aspects of the implant site. Twenty implant beds were prepared at 1200 rpm in clockwise (control) and counterclockwise (test) directions (N = 160). Optical coherence tomography (OCT) was used to evaluate the condensation and microarchitecture characteristics of the implant bed walls. The relative condensation was calculated using the Image J software Bone application. The microarchitecture was evaluated in reconstructed 3D volumes in XY, XZ, and YZ sections. Statistical analysis was performed using one-way ANOVA. Dunnet test was applied to determine differences between groups. Significance was set as p < 0.05. Results: Counterclockwise drilling (Test) condensed and changed the microarchitecture of the apical regions for all the implant beds in all of the groups when compared to clockwise drilling (control). The apical region of test groups showed the highest relative bone condensation (p = 0.026) when compared to controls. Conclusions: The direction of rotation (counterclockwise drilling) and not the design of tapered drills (tip and wall angles) is responsible for the condensation at the apical area observed in polyurethane blocks. The OCT method can be used for the evaluation of changes in density and microstructure of polyurethane blocks.


Assuntos
Osteotomia , Tomografia de Coerência Óptica , Análise de Variância , Humanos , Próteses e Implantes
16.
J Contemp Dent Pract ; 22(4): 327-334, 2021 Apr 01.
Artigo em Inglês | MEDLINE | ID: mdl-34266998

RESUMO

AIM AND OBJECTIVE: Coronally advanced flap (CAF) with connective tissue graft (CTG) has been considered the gold standard for obtaining complete root coverage. However, some limitations have been reported with the use of CTG, especially because it increases morbidity and leads to postoperative pain and bleeding. Recently, platelet-rich fibrin (PRF) has been used in periodontal plastic surgery for the treatment of gingival recessions (GRs). The aim of this study was to evaluate the outcome of PRF combined with a CAF (test) compared to de-epithelialized connective tissue graft (DeCTG) + CAF (control) for GR coverage. MATERIALS AND METHODS: Ten healthy patients exhibiting mandibular or maxillary Miller class I and II were treated with PRF + CAF or DeCTG + CAF. GR, probing depth (PD), and gingival thickness (GT) were evaluated at baseline, 6 weeks, and 28 weeks postoperatively. RESULTS: GR, PD, and GT differences between the test and control groups at 28 weeks were not statistically significant. GR was 3.30 ± 1.25 mm and 3.00 ± 1.63 mm (control vs test) group (baseline) and -0.10 ± 0.32 vs -0.20 ± 0.42 mm (7 months), respectively. CONCLUSION: Within the limitations of the present study, it can be concluded that localized gingival recessions could be successfully treated with CAF + PRF or CAF + DeCTG. CLINICAL SIGNIFICANCE: This study suggests that PRF membrane may be an alternative and valid graft material for treating localized gingival recessions Miller class I and II.


Assuntos
Retração Gengival , Fibrina Rica em Plaquetas , Tecido Conjuntivo , Gengiva , Retração Gengival/cirurgia , Humanos , Raiz Dentária , Resultado do Tratamento
17.
J Mater Sci Mater Med ; 31(10): 85, 2020 Sep 30.
Artigo em Inglês | MEDLINE | ID: mdl-33000320

RESUMO

The purpose of this study was to produce and characterize Hydroxyapatite/Zinc Oxide/Palladium (HA/0.05 wt% ZnO/0.1 wt% Pd) nanocomposite scaffolds and study their mechanical and antibacterial properties, biocompatibility and bioactivity. The initial materials were developed using sol-gel and precipitation methods. Scaffolds were characterized using atomic absorption analysis (AA), scanning electron microcopy (SEM), energy dispersive spectroscopy (EDS) and transmission electron microscopy (TEM), atomic force microscopy (AFM) and Brunauer-EmmeS-Teller (BET) method. Furthermore, the bioactivity of scaffolds in simulated body fluid (SBF) and the interaction of dental pulp stem cells (DPSCs) with the nanocomposite scaffolds were assessed. Our results showed that the HA/ZnO/Pd (H1), HA/ZnO/Pd coated by 0.125 g chitosan (H2) and HA/ZnO/Pd coated by 0.25 g chitosan (H3) scaffolds possess higher compressive strength and toughness and lower microhardness and density compared to the pure HA (H0) scaffolds. Immersion of samples in SBF showed the deposition of apatite on the surface of the scaffolds. The biocompatibility assay indicated lower cell proliferation on the H1, H2 and H3 in comparison to the H0. The antibacterial results obtained show a significant impact by loading Pd/ZnO on HA in the deactivation of microorganisms in vitro.


Assuntos
Substitutos Ósseos/química , Osso e Ossos , Durapatita/química , Nanocompostos/química , Paládio/química , Engenharia Tecidual/métodos , Óxido de Zinco/química , Antibacterianos/química , Materiais Biocompatíveis/química , Líquidos Corporais , Proliferação de Células , Quitosana/química , Força Compressiva , Humanos , Técnicas In Vitro , Concentração Inibidora 50 , Teste de Materiais , Microscopia de Força Atômica , Microscopia Eletrônica de Varredura , Nanopartículas , Nitritos/química , Porosidade , Pós , Pseudomonas aeruginosa , Alicerces Teciduais , Zinco
18.
Nutr Health ; 26(2): 135-139, 2020 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-32241225

RESUMO

BACKGROUND: It was hypothesized that pathological bleeding (PB) during and/or after oral surgical procedures is higher in systemically healthy patients who have a history of garlic intake compared to controls (patients without a history of garlic consumption). AIM: The aim of the present review article was to identify studies in which garlic consumption was included as a patient management protocol before and after oral and maxillofacial surgery (OMFS). METHODS: A review of pertinent indexed literature was performed. The focused question that was addressed was "Has diet (garlic consumption) been considered as a patient management protocol before and after OMFS?" The inclusion criteria were: (a) studies published in indexed databases, (b) original studies, (c) studies on OMFS, and (d) studies that considered diet (garlic consumption) as a patient management protocol before and after OMFS. Literature review, commentaries, letters to the editor, and studies published in non-indexed resources were excluded. The pattern of the present review was customized to summarize the pertinent information. RESULTS: The initial search using the terms "oral," maxillofacial," "protocol," and "surgery" yielded 1478 studies. The addition of the term "diet" to this search strategy reduced the number of studies to five. Further filtration of these studies using the terms "garlic" and/or "Allium sativum" showed no studies. CONCLUSIONS: Garlic intake predisposes patients to PB. However, there are no studies in the indexed literature that have considered the inclusion of garlic consumption in patient management protocols before and after OMFS.


Assuntos
Dieta/métodos , Alho/efeitos adversos , Hemorragia/epidemiologia , Cirurgia Bucal/métodos , Animais , Feminino , Hemorragia/prevenção & controle , Humanos , Masculino , Agregação Plaquetária , Hemorragia Pós-Operatória/epidemiologia , Guias de Prática Clínica como Assunto , Fatores de Risco
19.
J Relig Health ; 59(6): 2928-2934, 2020 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-31154591

RESUMO

The aim of the present review was to assess randomized controlled trials (RCTs) on bone grafting procedures that included religious belief as an eligibility criterion. Indexed databases were searched up to and including February 2019 using different search strategies. In strategy 1, the following terms were used: (a) belief; (b) bone graft; (c) faith; (d) inclusion; (e) exclusion; (f) eligibility; (g) criteria; (h) randomized clinical trial; (i) religion; and (j) xenograft. In strategy 2, the following terms were used in addition to those used in strategy 1: Xenografts AND oral surgery OR xenografts AND maxillofacial OR xenografts AND dental implants. These searches were filtered using the terms "Randomized clinical trial" and "human studies". The initial search yielded 3932 studies. Filtration of results using the terms "Randomized clinical trial" and "human studies" showed 0 studies. Evaluation of patients' religious beliefs seems to be undervalued in RCTs related to the placement of xenografts. This is an essential and ethical criterion that should be taken into consideration prior to inclusion of participants and signing the informed consent form for RCTs related to the placement of bone grafts.


Assuntos
Transplante Ósseo , Ensaios Clínicos Controlados Aleatórios como Assunto , Religião , Transplante Ósseo/ética , Transplante Ósseo/psicologia , Humanos , Princípios Morais
20.
Periodontol 2000 ; 81(1): 57-63, 2019 10.
Artigo em Inglês | MEDLINE | ID: mdl-31407442

RESUMO

It has been estimated that by 2030, the number of patients with diabetes aged > 64 years will be > 82 million in underdeveloped countries, and > 48 million in developed countries. Chronic hyperglycemia delays wound healing by reducing the expression of growth factors in the wound fluid and re-epithelialization. Impaired wound healing in patients with diabetes has also been associated with inhibition of the production of stromal cell-derived factor-1alpha by several tissues including bone marrow, brain, heart, spleen, and gingivae. Chronic hyperglycemia interferes with the osseointegration of implants by deferring the expression of fibronectin and integrins. Results from experimental studies have shown a significantly higher bone-to-implant contact around implants placed in healthy animals compared with animals with streptozotocin-induced diabetes. Moreover, persistent hyperglycemia plays a role in abnormal differentiation of osteoclasts, thereby making bone tissue more susceptible to resorption. Furthermore, persistent hyperglycemia has also been associated with increased peri-implant soft tissue inflammation (increased peri-implant bleeding on probing and probing depth) and crestal bone loss. Clinical studies have shown that under optimal glycemic control dental implants can show success and survival rates of up to 100% in patients diagnosed with diabetes. Although patients with diabetes can undergo dental implant therapy and can exhibit implant survival similar to those in systemically healthy individuals, the contribution of glycemic control and regular oral hygiene maintenance cannot be disregarded.


Assuntos
Perda do Osso Alveolar , Implantes Dentários , Hiperglicemia , Idoso , Animais , Implantação Dentária Endóssea , Seguimentos , Humanos , Osseointegração , Fatores de Risco
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