Detalhe da pesquisa
1.
Structural studies identify angiotensin II receptor blocker-like compounds as branched-chain ketoacid dehydrogenase kinase inhibitors.
J Biol Chem
; 299(3): 102959, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36717078
2.
An assessment of thermoneutral housing conditions on murine cardiometabolic function.
Am J Physiol Heart Circ Physiol
; 322(2): H234-H245, 2022 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34919456
3.
Protein Kinase Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) Promotes Obesity-induced Hyperinsulinemia.
J Biol Chem
; 291(31): 16221-30, 2016 07 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-27226575
4.
Map4k4 impairs energy metabolism in endothelial cells and promotes insulin resistance in obesity.
Am J Physiol Endocrinol Metab
; 313(3): E303-E313, 2017 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28611026
5.
The Lipid Droplet Protein Hypoxia-inducible Gene 2 Promotes Hepatic Triglyceride Deposition by Inhibiting Lipolysis.
J Biol Chem
; 290(24): 15175-84, 2015 Jun 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25922078
6.
ß3-Adrenergic receptor stimulation induces E-selectin-mediated adipose tissue inflammation.
J Biol Chem
; 288(4): 2882-92, 2013 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-23235150
7.
Mixed meal tolerance testing highlights in diabetes altered branched-chain ketoacid metabolism and pathways associated with all-cause mortality.
Am J Clin Nutr
; 117(3): 529-539, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36811472
8.
Branched-chain amino acid catabolism in muscle affects systemic BCAA levels but not insulin resistance.
Nat Metab
; 5(4): 589-606, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37100997
9.
Small molecule branched-chain ketoacid dehydrogenase kinase (BDK) inhibitors with opposing effects on BDK protein levels.
Nat Commun
; 14(1): 4812, 2023 08 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37558654
10.
BDK inhibition acts as a catabolic switch to mimic fasting and improve metabolism in mice.
Mol Metab
; 66: 101611, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36220546
11.
Lymphangiogenic therapy prevents cardiac dysfunction by ameliorating inflammation and hypertension.
Elife
; 92020 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33200983
12.
Myeloperoxidase inhibition in mice alters atherosclerotic lesion composition.
PLoS One
; 14(3): e0214150, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30889221
13.
Endothelial Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 Is Critical for Lymphatic Vascular Development and Function.
Mol Cell Biol
; 36(12): 1740-9, 2016 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27044870
14.
Adipocyte-specific Hypoxia-inducible gene 2 promotes fat deposition and diet-induced insulin resistance.
Mol Metab
; 5(12): 1149-1161, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27900258
15.
Peripartum Cardiomyopathy: Is It All in the Timing?
Hypertension
; 75(1): 33-34, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31707839
16.
NETs and traps delay wound healing in diabetes.
Trends Endocrinol Metab
; 26(9): 451-2, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26239304
17.
Hepatic mitogen-activated protein kinase phosphatase 1 selectively regulates glucose metabolism and energy homeostasis.
Mol Cell Biol
; 35(1): 26-40, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25312648
18.
Endothelial protein kinase MAP4K4 promotes vascular inflammation and atherosclerosis.
Nat Commun
; 6: 8995, 2015 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26688060
19.
IL-1 signaling in obesity-induced hepatic lipogenesis and steatosis.
PLoS One
; 9(9): e107265, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25216251
20.
The conserved misshapen-warts-Yorkie pathway acts in enteroblasts to regulate intestinal stem cells in Drosophila.
Dev Cell
; 31(3): 291-304, 2014 Nov 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-25453828