Detalhe da pesquisa
1.
The metabolic ER stress sensor IRE1α suppresses alternative activation of macrophages and impairs energy expenditure in obesity.
Nat Immunol
; 18(5): 519-529, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28346409
2.
Modulation of the HIF2α-NCOA4 axis in enterocytes attenuates iron loading in a mouse model of hemochromatosis.
Blood
; 139(16): 2547-2552, 2022 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34990508
3.
Reprogramming of Hepatic Metabolism and Microenvironment in Nonalcoholic Steatohepatitis.
Annu Rev Nutr
; 42: 91-113, 2022 08 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35584814
4.
Dysregulation of intercellular signaling by MOF deletion leads to liver injury.
J Biol Chem
; 296: 100235, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33376138
5.
Medullary thymic epithelial NF-kB-inducing kinase (NIK)/IKKα pathway shapes autoimmunity and liver and lung homeostasis in mice.
Proc Natl Acad Sci U S A
; 116(38): 19090-19097, 2019 09 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31481626
6.
Leptin Induces Epigenetic Regulation of Transient Receptor Potential Melastatin 7 in Rat Adrenal Pheochromocytoma Cells.
Am J Respir Cell Mol Biol
; 65(2): 214-221, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33891828
7.
A critical role for hepatic protein arginine methyltransferase 1 isoform 2 in glycemic control.
FASEB J
; 34(11): 14863-14877, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32918517
8.
Dual role for inositol-requiring enzyme 1α in promoting the development of hepatocellular carcinoma during diet-induced obesity in mice.
Hepatology
; 68(2): 533-546, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29506314
9.
Neural deletion of Sh2b1 results in brain growth retardation and reactive aggression.
FASEB J
; 32(4): 1830-1840, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29180441
10.
A small-molecule inhibitor of NF-κB-inducing kinase (NIK) protects liver from toxin-induced inflammation, oxidative stress, and injury.
FASEB J
; 31(2): 711-718, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27871061
11.
Thymic NF-κB-inducing kinase regulates CD4+ T cell-elicited liver injury and fibrosis in mice.
J Hepatol
; 67(1): 100-109, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28267623
12.
E4BP4 is an insulin-induced stabilizer of nuclear SREBP-1c and promotes SREBP-1c-mediated lipogenesis.
J Lipid Res
; 57(7): 1219-30, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27252523
13.
Carboxyl terminus of HSC70-interacting protein (CHIP) down-regulates NF-κB-inducing kinase (NIK) and suppresses NIK-induced liver injury.
J Biol Chem
; 290(18): 11704-14, 2015 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25792747
14.
Liver clock protein BMAL1 promotes de novo lipogenesis through insulin-mTORC2-AKT signaling.
J Biol Chem
; 289(37): 25925-35, 2014 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25063808
15.
Myeloid cell TRAF3 promotes metabolic inflammation, insulin resistance, and hepatic steatosis in obesity.
Am J Physiol Endocrinol Metab
; 308(6): E460-9, 2015 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25628422
16.
Role for the endoplasmic reticulum stress sensor IRE1α in liver regenerative responses.
J Hepatol
; 62(3): 590-8, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25457211
17.
Mouse hepatocyte overexpression of NF-κB-inducing kinase (NIK) triggers fatal macrophage-dependent liver injury and fibrosis.
Hepatology
; 60(6): 2065-76, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25088600
18.
PKA phosphorylation couples hepatic inositol-requiring enzyme 1alpha to glucagon signaling in glucose metabolism.
Proc Natl Acad Sci U S A
; 108(38): 15852-7, 2011 Sep 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-21911379
19.
Hepatic Snai1 and Snai2 promote liver regeneration and suppress liver fibrosis in mice.
Cell Rep
; 43(3): 113875, 2024 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38451818
20.
Mammalian IRE1α dynamically and functionally coalesces with stress granules.
Nat Cell Biol
; 2024 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38714852