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1.
Bull Cancer ; 108(12S): S1-S9, 2021 Dec.
Artigo em Francês | MEDLINE | ID: mdl-34176584

RESUMO

Allogeneic hematopoietic cell transplantation (allo-HCT), the only curative therapy for numerous hematological malignancies, carries a significant risk of morbidity and mortality. The patients and families' expectations regarding the procedure, the prognosis uncertainties, as well as the existence of potential new therapeutic possibilities, lead to frequent use of intensive care. Even though the transplant physicians are highly skilled in acute care, their knowledge of palliative approach is limited, making the use of palliative care insufficient and often late. By promoting reflection on the proportionality of care and the patients' quality of life, palliative care may contribute to the allo-HCT patients management. Nevertheless, obstacles to this approach remain. The objective of this work is to propose recommendations to promote the implementation of palliative care into transplant units.


Assuntos
Neoplasias Hematológicas/terapia , Transplante de Células-Tronco Hematopoéticas/efeitos adversos , Cuidados Paliativos , Diretivas Antecipadas , Aloenxertos , Atitude do Pessoal de Saúde , Proteínas de Bactérias , Criança , Tomada de Decisão Clínica , Deterioração Clínica , Glucosiltransferases , Pesquisas sobre Atenção à Saúde/métodos , Pesquisas sobre Atenção à Saúde/estatística & dados numéricos , Transplante de Células-Tronco Hematopoéticas/psicologia , Humanos , Comunicação Interdisciplinar , Relações Interprofissionais , Cuidados Paliativos/organização & administração , Cuidados Paliativos/psicologia , Prognóstico , Pesquisa Qualitativa , Qualidade de Vida , Sociedades Médicas , Assistência Terminal
2.
Bull Cancer ; 107(1S): S94-S103, 2020 Jan.
Artigo em Francês | MEDLINE | ID: mdl-31006487

RESUMO

Since 2010 there has been an exponential increase of the number of transplants performed from related donors. The development of haploidentical transplants increases the resort to related-donation, which presents two main advantages: a less important financial cost and a faster availability of the graft. Standards for mandatory accreditation exist, but the adherence to these recommendations is not optimal: currently, different practices regarding the organizational modalities of care, recruitment criteria, qualification and follow-up of related donors have been observed among French transplant centers. The Francophone Society of Marrow Transplant and Cellular Therapy (SFGM-TC) has developed guidelines for the consent and the non-eligibility criteria for hematopoietic stem cell donors. A multidisciplinary group has devised a booklet as a medium to inform donors about hematopoietic cell donation and transplantation in a clear and accessible language. This paper provides recommendations on post-donation follow-up, taking into account both medical standards and organizational constraints of French centers. Some tools are proposed.


Assuntos
Transplante de Células-Tronco Hematopoéticas , Doadores de Tecidos , Aloenxertos , Família , Haplótipos/genética , Histocompatibilidade , Humanos , Consentimento Livre e Esclarecido , Comunicação Interdisciplinar , Doadores Vivos , Obtenção de Tecidos e Órgãos/métodos , Obtenção de Tecidos e Órgãos/normas
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