The biomechanical role of the lacertus fibrosus of the biceps brachii Muscle.

PURPOSE: The lacertus fibrosus (LF) is involved in various surgeries. However, the biomechanical contribution of the LF remains unclear. The aim of this study was to determine the role of the lacertus fibrosus on the elbow and forearm kinematics and on the biceps brachii muscle lever arms. METHODS: This biomechanical study was performed on seven fresh-frozen upper limbs of cadavers. Elbow flexion, forearm supination, and biceps brachii muscle lever arms were analyzed in the intact conditions (I) and after superficial (R) and deep part (R2) of the lacertus fibrosus release, respectively. RESULTS: Elbow flexion shows a significant difference (p < 0.0001) between I, R, R2. Abduction/adduction shows a significant difference between I-R (p < 0.0001) and I-R2 (p < 0.0001). Supination does not show a significant difference in mean maximum amplitude, but between 40 and 70%, there are significant differences. There is a significant mean decrease of lever arm in flexion (28%) and supination (50%) after superficial and deep part of the lacertus fibrosus release. CONCLUSION: The results of this study show that the lacertus fibrosus increases the lever arm during flexion and supination. It limits the flexion and abduction of the elbow and supination of the forearm. Lacertus fibrosus maintains the rhythmicity between the elbow flexion and supination of the forearm. LEVEL OF EVIDENCE: Basic science study, biomechanics.

Three-Corner Arthrodesis (lunate - hamate - capitate) : clinical and kinematical evaluation.

In the absence of prosthetic arthroplasty offering good results for the treatment of wrist osteoarthritis, we studied the arthrodesis of three carpal bones (lunate - hamate - capitate) completed by triquetrum and scaphoid excision in the presence of Scapholunate Advanced Collapse (SLAC) or Scaphoid Nonunion Advanced Collapse (SNAC) stage II or III. Clinical data on eight patients between the ages of 32 and 61 years at an average of 29 months after surgery was analyzed. Seven patients reached fusion with a carpal height ratio of 0.39. These arc of dorsal-palmar flexion (DPF) attended 54° and the arc of radio-ulnar deviation (RUD) 29° using the optoelectronic stereophotogrammetry system. The mean polar radius (R) was 14.5° and the envelope shape coefficient (K) was 1.66. This operation could be considered as an alternative for the treatment of patients suffering of SNAC or SLAC stage II and III. Type of study/level of evidence : Therapeutic IV.

Head-trunk kinematics during high-velocity-low-amplitude manipulation of the cervical spine in asymptomatic subjects: helical axis computation and anatomic motion modeling.

OBJECTIVE: This study aimed to analyze the in vivo 3-dimensional kinematics of the head during cervical manipulation including helical axis (HA) computation and anatomic motion representation. METHODS: Twelve asymptomatic volunteers were included in this study. An osteopathic practitioner performed 1 to 3 manipulations (high-velocity and low-amplitude [HVLA] multiple component technique) of the cervical spine (between C2 and C5) with the patient in the sitting position. During manipulation, head motion was collected using an optoelectronic system and expressed relative to the thorax. Motion data were processed to analyze primary and coupled motions and HA parameters. Anatomic motion representation including HA was obtained. RESULTS: During manipulation, average maximal range of motion was 39° (SD, 6°), 21° (SD, 7°), and 8° (SD, 5°) for lateral bending (LB), axial rotation (AR), and flexion extension, respectively. For the impulse period, magnitude averaged of 8° (SD, 2°), 5° (SD, 2°), and 3° (SD, 2°), for LB, AR, and flexion extension, respectively. Mean impulse velocity was 139°/s (SD, 39°/s). Concerning AR/LB ratios, an average of 0.6 (SD, 0.3) was observed for global motion, premanipulation positioning, and impulse. Mean HA was mostly located ipsilateral to the impulse side and displayed an oblique orientation. CONCLUSION: This study demonstrated limited range of AR during cervical spine manipulation and provided new perspectives for the development of visualization tools, which might be helpful for practitioners and for the analysis of cervical manipulation using HA computation and anatomic representation of motion.

Influence of movement speed on cervical range of motion.

PURPOSE: Cervical range of motion (RoM) has been the subject of many studies. However, only very few of these studies have considered the influence of movement execution speed on the cervical kinematics. The aim of this study is to evaluate the influence of movement speed on cervical RoM. METHOD: Cervical RoM was recorded using an optoelectronic system; 32 healthy subjects performed movements in two modes: the best possible and as fast as possible. OUTCOME MEASURES: The primary movements (flexion-extension, lateral bending, axial rotation) and coupled movements were studied. Paired Student's tests were performed to compare the two modes of movement. RESULTS: The results showed that cervical RoM differed significantly between movement speeds. Amplitudes were higher for each movement (p < 0.001 for flexion-extension, p < 0.001 for lateral flexion, p = 0.008 for axial rotations) when movements were performed as quickly as possible. The range of movements carried out the best possible reached only 95% of those during movements carried out as fast as possible. Concerning coupled movements, an increase in rotational movements coupled to lateral flexion during fast movements was observed. CONCLUSION: The range of motion reported in the literature corresponds to movement carried out in a mode resembling the best possible of our study. Movements made as quickly as possible can display larger motion ranges.

[A technological platform for cerebral palsy - the ICT4Rehab project]. / Une plate-forme technologique liée à la paralysie cérébrale - le projet ICT4Rehab.

The musculoskeletal system (MSS) is essential to allow us performing every-day tasks, being able to have a professional life or developing social interactions with our entourage. MSS pathologies have a significant impact on our daily life. It is therefore not surprising to find MSS-related health problems at the top of global statistics on professional absenteeism or societal health costs. The MSS is also involved in central nervous conditions, such as cerebral palsy (CP). Such conditions show complex etiology that complicates the interpretation of the observable clinical signs and the establishment of a wide consensus on the best practices to adopt for clinical monitoring and patient follow-up. These elements justify the organization of fundamental and applied research projects aiming to develop new methods to help clinicians to cope with the complexity of some MSS disorders. The ICT4Rehab project (www.ict4rehab.org) developed an integrated platform providing tools that enable easier management and visualization of clinical information related to the MSS of CP patients. This platform is opened to every interested clinical centre.

In vitro biomechanical study of femoral torsion disorders: effect on tibial proximal epiphyseal cancellous bone deformation.

PURPOSE: Osteoarthritis (OA) of the knee is a degenerative disease mainly found in elderly population. Valgus deformity seems to be directly related to lateralised gonarthrosis. Contradictory outcomes of surgical series are published in the literature and report satisfactory and unsatisfactory long-term results. Lower limb torsions disorders have been considered as being another factor inducing gonarthrosis. This paper presents an in vitro study aiming at quantifying the relationships between experimental femoral torsion disorders (medial and lateral) and the deformation of the cancellous bone of the proximal tibial epiphysis (CB(TPE)). METHODS: Five left fresh-frozen lower limbs were used. Specimens were mounted on an experimental jig and muscles were loaded. Six measurement elements, including strain gages, were introduced into CB(TPE) to measure relative deformation. Experimental osteotomy control was performed using a specially devised system allowing various amplitudes of medial and lateral torsion. CB(TPE) deformations were measured during knee flexion movement. RESULTS: Intra-observer reproducibility of CB(TPE) deformations showed a mean coefficient of multiple correlation of 0.93 and a mean coefficient of variation of 9% for flexion. Intra-specimen repeatability showed a mean RMS difference ranging from 7 to 10% and a mean ICC of 0.98. CB(TPE) deformations were significantly influenced by femoral torsion disorder conditions and range-of-motion (ROM) for most measurement elements. No interaction between torsion condition and ROM was observed. Globally, CB(TPE) deformation in the lateral compartment increased during experimental lateral torsion disorder simulation and decreased during medial torsion simulation. The opposite behaviour was observed in the medial compartment. The decrease and/or increase were not always proportional to the degree of femoral torsional disorder simulated. CONCLUSION: Experimental results from this study do not fully agree with previously published clinical observations on the femoral torsion disorder. The present quantified results do not support that medial femoral torsion disorder induces an increased lateral tibial deformation, which could be linked to gonarthrosis observed in this compartment. In summary, our results showed that medial and lateral femoral torsion disorder conditions applied in normally aligned lower limb induced a deformation increase in the medial and in the lateral compartment, respectively.

In vitro 3D-kinematics of the upper cervical spine: helical axis and simulation for axial rotation and flexion extension.

PURPOSE: Registration of 3D-anatomical model and kinematics data is reported to be an accurate method to provide 3D-joint simulation. We applied this approach to discrete kinematics analysis of upper cervical spine (UCS) during axial rotation (AR) and flexion extension (FE) to create anatomical models with movement simulation including helical axis. METHODS: Kinematics and CT imaging data were sampled in ten anatomical specimens. Using technical and anatomical marker digitizing, spatial position of segments was computed for five discrete positions of AR and FE using a 3D-digitizer. Computerized tomography was used to create anatomical models and to assure kinematics and imaging data registration for simulation. Kinematics was processed using orientation vector and helical axis (HA) computation. RESULTS: Maximal standard error on marker digitizing was 0.47 mm. Range of motion and coupled movement during AR was in agreement with previous in vitro studies. HA location and orientation have shown low variation at the occipitoaxial and atlantoaxial levels for FE and AR, respectively. CONCLUSIONS: We developed a protocol to create UCS anatomical model simulations including three-dimensional discrete kinematics, using previously validated methods. In this study, simultaneous segmental movement simulation and display of HA variations was shown to be feasible. Although partially confirming previous results, helical axis computation showed variations of motion patterns dependent on movement, level and specimen. Further in vivo investigations are needed to confirm relevance of this method in the clinical field.

Neck movement speed in cervical dystonia.

Clinical scales of patients with cervical dystonia do not rate neck movement velocity. We prospectively measured range of neck movements and movement velocities in 35 consecutive patients with cervical dystonia (CD) and 29 normal controls. Reduction of peak velocities in patients with CD was the most robust abnormality and was correlated to TWSTRS. Coupled movements out of attempted movement plane were increased in the patient group. Movement range was moderately though significantly reduced. We conclude that slowing of voluntary neck movements is a frequent and hitherto unrecognized feature in CD.

Metatarsal arch deformation and forefoot kinematics during gait in asymptomatic subjects.

This study aimed to investigate both foot arch-shaped architecture and forefoot kinematics during gait. Using a dedicated three-compartment forefoot subdivision, we studied asymptomatic subjects and quantified disorders related to the metatarsal arch. Foot motion and arch shape were measured in 30 healthy subjects with a motion-capture system and force plates. Kinematic results were expressed using a novel model, which anatomically divides the forefoot into three parts. This model integrated the medial longitudinal arch angle and the metatarsal arch height and width. During the first part of stance phase, the medial longitudinal arch flattens and all foot segments move toward dorsiflexion. During terminal stance and preswing phase, medial longitudinal and metatarsal arch restoration was noted with plantarflexion of all segments, an eversion and abduction of the medial forefoot, and an inversion and adduction of the lateral forefoot. Kinematics obtained with the proposed forefoot model corroborates metatarsal arch restoration in late stance. This observation supports the fact that foot architecture is supple until midstance and subsequently creates a rigid lever arm with restored arches to support propulsion. This study's results and methods highlight the potential of the three-compartment model for use in clinical decision-making.

Double-step registration of in vivo stereophotogrammetry with both in vitro 6-DOFs electrogoniometry and CT medical imaging.

Standard registration techniques of bone morphology to motion analysis data often lead to unsatisfactory motion simulation because of discrepancies during the location of anatomical landmarks in the datasets. This paper describes an iterative registration method of a three-dimensional (3D) skeletal model with both 6 degrees-of-freedom joint kinematics and standard motion analysis data. The method is demonstrated in this paper on the lower limb. The method includes two steps. A primary registration allowed synchronization of in vitro kinematics of the knee and ankle joints using flexion/extension angles from in vivo gait analysis. Results from primary registration were then improved by a so-called advanced registration, which integrated external constraints obtained from experimental gait pre-knowledge. One cadaver specimen was analyzed to obtain both joint kinematics of knee and ankle joints using 3D electrogoniometry, and 3D bone morphology from medical imaging data. These data were registered with motion analysis data from a volunteer during the execution of locomotor tasks. Computer graphics output was implemented to visualize the results for a motion of sitting on a chair. Final registration results allowed the observation of both in vivo motion data and joint kinematics from the synchronized specimen data. The method improved interpretation of gait analysis data, thanks to the combination of realistic 3D bone models and joint mechanism. This method should be of interest both for research in gait analysis and medical education. Validation of the overall method was performed using RMS of the differences between bone poses estimated after registration and original data from motion analysis.

In vivo registration of both electrogoniometry and medical imaging: development and application on the ankle joint complex.

An in vivo method for joint kinematics visualization and analysis is described. Low-dose computed tomography allowed three-dimensional joint modeling, and electrogoniometry collected joint kinematic data. Data registration occurred using palpated anatomical landmarks to obtain interactive computer joint simulation. The method was applied on one volunteer's ankle, and reproducibility was tested (maximal discrepancy: 3.6 deg and 5.5 mm for rotation and translation respectively).

Clinical and goniometric evaluation of patients with spasmodic torticollis.

BACKGROUND: Patients with cervical dystonia have been evaluated prospectively by the Toronto Western Spasmodic Torticollis Rating Scale and by cervical electrogoniometry. METHODS: Nineteen patients with cervical dystonia were studied. The Toronto Scale interobserver reliability was evaluated by two observers. An electrogoniometer was used to quantify cervical range of motion and velocity. The correlation between goniometric measurements and clinical evaluation was calculated. FINDINGS: The interobserver reliability was excellent for the total score (r(s) = 99) and good for the disability and the pain score (r > 0.88). However, global severity scale was shown to have a moderate reliability (r = 0.63) with r ranging from 0.37 to 0.98 for the individual items. The average loss of range of motion for flexion and extension, lateral bending and rotation was 18%, 12% and 21% respectively. For the velocity of movement, the average loss was proportionately greater than for the range of motion. (41%, 43% and 52% respectively). Correlation between the severity scale and range of motion was moderate but significant (r(s) = -0.52 to -0.67). Correlation between the Toronto severity score and the sum of movement velocities was significant for flexion-extension and lateral bending velocity sums (r(s) = -0.51; r(s) = -0.61). The lateral bending and rotation velocities were significantly correlated with pain and total scores (r(s) = -0.51). No significant correlation was observed for the disability score. INTERPRETATION: Three-dimensional electrogoniometry is helpful to quantify the velocity of neck movements and range of motion in patients with cervical dystonia.

Low-dose computed tomography: a solution for in vivo medical imaging and accurate patient-specific 3D bone modeling?

BACKGROUND: The number of in vivo clinical biomedical experiments based on computed tomography is increasing. International radiation-protection bodies are promoting the use of low-dose computed tomography to reduce radiation absorption by the subject undergoing imaging. On the other hand no data exist in the literature to quantify whether or not low-dose computed tomography would lead to a decrease of result quality when used for three-dimensional bone modeling and related measurements. METHODS: This paper aimed at finding a consensus between minimal X-ray radiation of the subject, and satisfactory image data quality, especially for accurate three-dimensional bone modeling. Several standard computed tomography and low-dose computed tomography sequences were analyzed in three tests and statistically compared. FINDINGS: Absence of significant difference between standard and low-dose computed sequences indicated that the low-dose setting would not produce less accurate three-dimensional models, while it decreased the effective X-ray dose up to 90% compared to standard settings. INTERPRETATION: Low-dose computed tomography seems suitable for accurate three-dimensional bone modeling, while the related effective X-ray radiation is low. Such setting is therefore advised for any in vivo medical imaging aiming to collect bone data.

Physiologically corrected coupled motion during gait analysis using a model-based approach.

Gait analysis is used in daily clinics for patients' evaluation and follow-up. Stereophotogrammetric devices are the most used tool to perform these analyses. Although these devices are accurate results must be analyzed carefully due to relatively poor reproducibility. One of the major issues is related to skin displacement artifacts. Motion representation is recognized reliable for the main plane of motion displacement, but secondary motions, or combined, are less reliable because of the above artifacts. Model-based approach (MBA) combining accurate joint kinematics and motion data was previously developed based on a double-step registration method. This study presents an extensive validation of this MBA method by comparing results with a conventional motion representation model. Thirty five healthy subjects participated to this study. Gait motion data were obtained from a stereophotogrammetric system. Plug-in Gait model (PiG) and MBA were applied to raw data, results were then compared. Range-of-motion, were computed for pelvis, hip, knee and ankle joints. Differences between PiG and MBA were then computed. Paired-sample t-tests were used to compare both methods. Normalized root-mean square errors were also computed. Shapes of the curves were compared using coefficient of multiple correlations. The MBA and PiG approaches shows similar results for the main plane of motion displacement but statistically significative discrepancies appear for the combined motions. MBA appear to be usable in applications (such as musculoskeletal modeling) requesting better approximations of the joints-of-interest thanks to the integration of validated joint mechanisms.

Effect of anatomical landmark perturbation on mean helical axis parameters of in vivo upper costovertebral joints.

The literature concerning quantification of costovertebral joint (CVJ) motion under in vivo conditions is scarce. Most papers concerning this topic are related to ex vivo loading conditions. In vivo protocols are available from the literature to determine rib and vertebra kinematics but new developments are needed to improve data processing concerning CVJ behaviour obtained from discrete breathing positions showing limiting ranges-of-motion and sensitive to noise. Data from previous work were used to implement a method analyzing mean helical axis (MHA) and pivot point parameters of the CVJ complexes. Several levels of noises were estimated within Monte-Carlo simulations to optimize MHA results. MHA parameters were then used to transform and define a CVJ-specific local coordinate system. This study proposes an improvement for CVJ kinematics processing and description from in vivo data obtained from computed tomography. This methodology emphasizes the possibility to work with variability of MHA parameters using Monte-Carlo procedures on anatomical landmark coordinates and to define a local coordinate system from this particular joint behaviour. Results from the CVJ joint model are closer to a hinge joint (secondary motions inferior to 3°) when anatomical frames are expressed from MHA orientation. MHA orientation and position data obtained from the proposed method are relevant according to angular dispersion obtained (from 7.5° to 13.9°) and therefore relevant to define behaviour of CVJ.

Development of multimedia learning modules for teaching human anatomy: application to osteology and functional anatomy.

Computer-assisted learning (CAL) is growing quickly within academic programs. Although the anatomical commercial packages that are available for this learning have attractive advantages, they also have drawbacks: they are frequently not in the local language of the students, they do not perfectly answer the needs of the local academic program, and their cost is frequently more than students can afford. This study describes a relatively inexpensive method to create CAL tutorials, whose content can be fully customized to local academic needs in terms of both program and language. The study describes its use in creating multimedia learning modules (MLMs) about Osteology and joint kinematics. The pedagogical content in these modules was collected from objective experiments to give students the opportunity to access new scientific knowledge during their education. It can be replaced, as desired, by almost any content due to the flexibility of the production method. Each MLM consists of two complementary subelements: a multimedia theoretical lecture and a three-dimensional interactive laboratory. Such MLMs are in use at both the University of Brussels (ULB) and the National University of Rwanda (NUR). The development of this work was part of the VAKHUM project, and the pedagogical validation is currently being performed as part of the MULTIMOD project.

Data representation for joint kinematics simulation of the lower limb within an educational context.

Three-dimensional (3D) visualization is becoming increasingly frequent in both qualitative and quantitative biomechanical studies of anatomical structures involving multiple data sources (e.g. morphological data and kinematics data). For many years, this kind of experiment was limited to the use of bi-dimensional images due to a lack of accurate 3D data. However, recent progress in medical imaging and computer graphics has forged new perspectives. Indeed, new techniques allow the development of an interactive interface for the simulation of human motions combining data from both medical imaging (i.e., morphology) and biomechanical studies (i.e., kinematics). Fields of application include medical education, biomechanical research and clinical research. This paper presents an experimental protocol for the development of anatomically realistic joint simulation within a pedagogical context. Results are shown for the lower limb. Extension to other joints is straightforward. This work is part of the Virtual Animation of the Kinematics of the Human project (VAKHUM) (http://www.ulb.ac.be/project/vakhum).

Calibration and validation of 6 DOFs instrumented spatial linkage for biomechanical applications. A practical approach.

A method for both calibration and validation of a 6 DOF electrogoniometer is presented. A 6 Revolute Instrumented Spatial Linkage (6R-ISL) and a three-dimensional digitizer (3DD) were used simultaneously to collect both static and continuous poses of unconstrained or constrained motions. Validation occurred using a calibrated ball-and-socket joint. A parametrical model of the 6R-ISL (i.e. Virtual Goniometer or VG) was designed using a standard multibody system geometry. Two approaches were used to adjust the VG parameters: a parametrical adjustment of the VG linkage geometry, and a functional adjustment of the potentiometer calibration curves (angle-voltage) in a predefined range of motion. After calibration, 6R-ISL accuracy was better than 1 mm and 1 degrees for translation and orientation, respectively. The functional method presented in this paper can be suggested as a practical approach, which allows on-line checking and calibration of 6R-ISL within the specific range of interest of a particular anatomical joint. In addition, improving the potentiometer calibration curves was less time consuming than the parametrical adjustment.

Development of kinematics tests for the evaluation of lumbar proprioception and equilibration.

OBJECTIVE: This study aimed at developing lumbar repositioning and seated equilibration tests. DESIGN: 3D-electrogoniometric study of trunk repositioning and equilibration in seated position. BACKGROUND: Postural equilibrium and lumbar proprioception alterations have been shown in patients with low-back pain. METHODS: In 21 healthy volunteers, pure flexion and flexion+rotation repositioning error was measured using 3D-electrogoniometry. Lumbar kinematics was analysed (time and frequency domain) during antero-posterior and lateral equilibration tests in seated position. Reproducibility and stability of the protocol were evaluated. RESULTS: Reproducibility and stability were good. Pure flexion repositioning error was similar to previous reports. For flexion+rotation tests, repositioning error was 3 degrees for flexion and 1 degrees for rotation. Amplitude, imbalance time and power spectrum were significantly larger in lateral than in antero-posterior equilibration tests. CONCLUSIONS: The feasibility of kinematic analysis of lumbar repositioning and equilibration was shown. Repositioning error values were in agreement with previous studies. New tests and parameters were proposed. Lateral equilibration tests appeared more demanding than antero-posterior tests. RELEVANCE: In patients with low-back pain, lumbar repositioning and equilibration tests may be of use to define rehabilitation strategies and to evaluate treatment outcome.

The use of medical imaging-based kinematic analysis in the evaluation of wrist function and outcome.

The authors developed a 3D CT technique to analyze in vivo variations in carpal bone position based on 3D reconstruction of transverse CT data in 5 wrist positions. The subject groups analyzed consisted of 40 asymptomatic volunteers and 30 patients with various wrist disorders (fractures, instabilities). In 11 anatomic specimens, this kinematic analysis was completed by a radiographic morphologic study and an investigation of capsular ligament anatomy. Clinical applications showed that carpal bone motion in the injured wrist was not significantly different from contralateral, asymptomatic wrist motion. In both wrists of patients with unilateral pathology, however, significant differences were observed as compared with asymptomatic volunteers. Scaphoid motion was bilaterally altered, suggesting the existence of anatomic or kinematic factors predisposing to certain carpal pathologies.