Detalhe da pesquisa
1.
Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma.
Cell
; 181(6): 1329-1345.e24, 2020 06 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32445698
2.
Oncogenic chimeric transcription factors drive tumor-specific transcription, processing, and translation of silent genomic regions.
Mol Cell
; 82(13): 2458-2471.e9, 2022 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35550257
3.
Failure of human rhombic lip differentiation underlies medulloblastoma formation.
Nature
; 609(7929): 1021-1028, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36131014
4.
Author Correction: Failure of human rhombic lip differentiation underlies medulloblastoma formation.
Nature
; 612(7940): E12, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36446943
5.
ERG transcription factors have a splicing regulatory function involving RBFOX2 that is altered in the EWS-FLI1 oncogenic fusion.
Nucleic Acids Res
; 49(9): 5038-5056, 2021 05 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34009296
6.
ZRANB2 and SYF2-mediated splicing programs converging on ECT2 are involved in breast cancer cell resistance to doxorubicin.
Nucleic Acids Res
; 48(5): 2676-2693, 2020 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31943118
7.
A therapeutically targetable positive feedback loop between lnc-HLX-2-7, HLX, and MYC that promotes group 3 medulloblastoma.
Cell Rep
; 43(3): 113938, 2024 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38460130
8.
Lymphatic endothelial-like cells promote glioblastoma stem cell growth through cytokine-driven cholesterol metabolism.
Nat Cancer
; 5(1): 147-166, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38172338
9.
Hedgehog target genes regulate lipid metabolism to drive basal cell carcinoma and medulloblastoma.
Res Sq
; 2023 Aug 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37577529
10.
The LIN28B-let-7-PBK pathway is essential for group 3 medulloblastoma tumor growth and survival.
Mol Oncol
; 17(9): 1784-1802, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37341142
11.
Targeting Microglial Metabolic Rewiring Synergizes with Immune-Checkpoint Blockade Therapy for Glioblastoma.
Cancer Discov
; 13(4): 974-1001, 2023 04 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36649564
12.
miRNA-211 maintains metabolic homeostasis in medulloblastoma through its target gene long-chain acyl-CoA synthetase 4.
Acta Neuropathol Commun
; 11(1): 203, 2023 Dec 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38115140
13.
A neurodevelopmental epigenetic programme mediated by SMARCD3-DAB1-Reelin signalling is hijacked to promote medulloblastoma metastasis.
Nat Cell Biol
; 25(3): 493-507, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36849558
14.
Combined MEK and JAK/STAT3 pathway inhibition effectively decreases SHH medulloblastoma tumor progression.
Commun Biol
; 5(1): 697, 2022 07 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35835937
15.
An OTX2-PAX3 signaling axis regulates Group 3 medulloblastoma cell fate.
Nat Commun
; 11(1): 3627, 2020 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32686664
16.
Transcriptional Programs Define Intratumoral Heterogeneity of Ewing Sarcoma at Single-Cell Resolution.
Cell Rep
; 30(6): 1767-1779.e6, 2020 02 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32049009
17.
scRNA-seq in medulloblastoma shows cellular heterogeneity and lineage expansion support resistance to SHH inhibitor therapy.
Nat Commun
; 10(1): 5829, 2019 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31863004
18.
Author Correction: scRNA-seq in medulloblastoma shows cellular heterogeneity and lineage expansion support resistance to SHH inhibitor therapy.
Nat Commun
; 13(1): 3048, 2022 May 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-35618754
19.
TCF12 is mutated in anaplastic oligodendroglioma.
Nat Commun
; 6: 7207, 2015 Jun 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-26068201
20.
Combined analysis of TERT, EGFR, and IDH status defines distinct prognostic glioblastoma classes.
Neurology
; 83(13): 1200-6, 2014 Sep 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25150284