Detalhe da pesquisa
1.
Loss of MED12 activates the TGFß pathway to promote chemoresistance and replication fork stability in BRCA-deficient cells.
Nucleic Acids Res
; 49(22): 12855-12869, 2021 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34871431
2.
Dual genome-wide CRISPR knockout and CRISPR activation screens identify mechanisms that regulate the resistance to multiple ATR inhibitors.
PLoS Genet
; 16(11): e1009176, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33137164
3.
Genome-wide CRISPR synthetic lethality screen identifies a role for the ADP-ribosyltransferase PARP14 in DNA replication dynamics controlled by ATR.
Nucleic Acids Res
; 48(13): 7252-7264, 2020 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32542389
4.
PARP10 promotes cellular proliferation and tumorigenesis by alleviating replication stress.
Nucleic Acids Res
; 46(17): 8908-8916, 2018 09 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30032250
5.
CRISPR screens guide the way for PARP and ATR inhibitor biomarker discovery.
FEBS J
; 289(24): 7854-7868, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34601817
6.
Lagging strand gap suppression connects BRCA-mediated fork protection to nucleosome assembly through PCNA-dependent CAF-1 recycling.
Nat Commun
; 13(1): 5323, 2022 09 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36085347
7.
The TIP60-ATM axis regulates replication fork stability in BRCA-deficient cells.
Oncogenesis
; 11(1): 33, 2022 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35717336
8.
Complementary CRISPR genome-wide genetic screens in PARP10-knockout and overexpressing cells identify synthetic interactions for PARP10-mediated cellular survival.
Oncotarget
; 13: 1078-1091, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36187556
9.
Interactions between the WEE-1.3 kinase and the PAM-1 aminopeptidase in oocyte maturation and the early C. elegans embryo.
G3 (Bethesda)
; 11(4)2021 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33681968
10.
Identification of regulators of poly-ADP-ribose polymerase inhibitor response through complementary CRISPR knockout and activation screens.
Nat Commun
; 11(1): 6118, 2020 11 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-33257658
11.
Tristetraprolin targets Nos2 expression in the colonic epithelium.
Sci Rep
; 9(1): 14413, 2019 10 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31595002
12.
PARI (PARPBP) suppresses replication stress-induced myeloid differentiation in leukemia cells.
Oncogene
; 38(27): 5530-5540, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30967629