Detalhe da pesquisa
1.
Crystal structure of the HLA-DM-HLA-DR1 complex defines mechanisms for rapid peptide selection.
Cell
; 151(7): 1557-68, 2012 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-23260142
2.
HLA-DM captures partially empty HLA-DR molecules for catalyzed removal of peptide.
Nat Immunol
; 12(1): 54-61, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21131964
3.
Identification of ß-Glucocerebrosidase Activators for Glucosylceramide hydrolysis.
ChemMedChem
; 19(7): e202300548, 2024 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38381042
4.
Discovery of ginisortamab, a potent and novel anti-gremlin-1 antibody in clinical development for the treatment of cancer.
MAbs
; 15(1): 2289681, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38084840
5.
Modulation of IL-17 backbone dynamics reduces receptor affinity and reveals a new inhibitory mechanism.
Chem Sci
; 14(27): 7524-7536, 2023 Jul 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37449080
6.
Designing Out PXR Activity on Drug Discovery Projects: A Review of Structure-Based Methods, Empirical and Computational Approaches.
J Med Chem
; 64(10): 6413-6522, 2021 05 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34003642
7.
The Chemical Synthesis of Knob Domain Antibody Fragments.
ACS Chem Biol
; 16(9): 1757-1769, 2021 09 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34406751
8.
Optimization of 8-Hydroxyquinolines as Inhibitors of Catechol O-Methyltransferase.
J Med Chem
; 61(21): 9647-9665, 2018 11 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30272964
9.
Disruption of hydrogen bonds between major histocompatibility complex class II and the peptide N-terminus is not sufficient to form a human leukocyte antigen-DM receptive state of major histocompatibility complex class II.
PLoS One
; 8(7): e69228, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23976922
10.
The mechanism of HLA-DM induced peptide exchange in the MHC class II antigen presentation pathway.
Curr Opin Immunol
; 24(1): 105-11, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22138314