Detalhe da pesquisa
1.
The adenylate cyclase toxin RTX domain follows a series templated folding mechanism with implications for toxin activity.
J Biol Chem
; 299(9): 105150, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37567473
2.
A conserved tryptophan in the acylated segment of RTX toxins controls their ß2 integrin-independent cell penetration.
J Biol Chem
; 299(8): 104978, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37390987
3.
The Fim and FhaB adhesins play a crucial role in nasal cavity infection and Bordetella pertussis transmission in a novel mouse catarrhal infection model.
PLoS Pathog
; 18(4): e1010402, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35395059
4.
Pertussis toxin suppresses dendritic cell-mediated delivery of B. pertussis into lung-draining lymph nodes.
PLoS Pathog
; 18(6): e1010577, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35666769
5.
Calcium-Driven Folding of RTX Domain ß-Rolls Ratchets Translocation of RTX Proteins through Type I Secretion Ducts.
Mol Cell
; 62(1): 47-62, 2016 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27058787
6.
Almost half of the RTX domain is dispensable for complement receptor 3 binding and cell-invasive activity of the Bordetella adenylate cyclase toxin.
J Biol Chem
; 297(1): 100833, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34051233
7.
Cytotoxicity of the effector protein BteA was attenuated in Bordetella pertussis by insertion of an alanine residue.
PLoS Pathog
; 16(8): e1008512, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32776984
8.
Overcoming Waning Immunity in Pertussis Vaccines: Workshop of the National Institute of Allergy and Infectious Diseases.
J Immunol
; 205(4): 877-882, 2020 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32769142
9.
Filamentous Hemagglutinin of Bordetella pertussis Does Not Interact with the ß2 Integrin CD11b/CD18.
Int J Mol Sci
; 23(20)2022 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36293453
10.
Retargeting from the CR3 to the LFA-1 receptor uncovers the adenylyl cyclase enzyme-translocating segment of Bordetella adenylate cyclase toxin.
J Biol Chem
; 295(28): 9349-9365, 2020 07 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32393579
11.
Acyltransferase-mediated selection of the length of the fatty acyl chain and of the acylation site governs activation of bacterial RTX toxins.
J Biol Chem
; 295(28): 9268-9280, 2020 07 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32461253
12.
Bacterial RTX toxins and host immunity.
Curr Opin Infect Dis
; 34(3): 187-196, 2021 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33899753
13.
Selective Enhancement of the Cell-Permeabilizing Activity of Adenylate Cyclase Toxin Does Not Increase Virulence of Bordetella pertussis.
Int J Mol Sci
; 22(21)2021 Oct 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34769101
14.
Bordetella Adenylate Cyclase Toxin Elicits Airway Mucin Secretion through Activation of the cAMP Response Element Binding Protein.
Int J Mol Sci
; 22(16)2021 Aug 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34445770
15.
Bordetellapertussis Acetylome is Shaped by Lysine Deacetylase Bkd1.
J Proteome Res
; 19(9): 3680-3696, 2020 09 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32674575
16.
Intrinsically disordered proteins drive enamel formation via an evolutionarily conserved self-assembly motif.
Proc Natl Acad Sci U S A
; 114(9): E1641-E1650, 2017 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28196895
17.
cAMP Signaling of Adenylate Cyclase Toxin Blocks the Oxidative Burst of Neutrophils through Epac-Mediated Inhibition of Phospholipase C Activity.
J Immunol
; 198(3): 1285-1296, 2017 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28039302
18.
Bordetella pertussis Adenylate Cyclase Toxin Disrupts Functional Integrity of Bronchial Epithelial Layers.
Infect Immun
; 86(3)2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29203545
19.
Cyclic AMP-Elevating Capacity of Adenylate Cyclase Toxin-Hemolysin Is Sufficient for Lung Infection but Not for Full Virulence of Bordetella pertussis.
Infect Immun
; 85(6)2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28396322
20.
cAMP signalling of Bordetella adenylate cyclase toxin through the SHP-1 phosphatase activates the BimEL-Bax pro-apoptotic cascade in phagocytes.
Cell Microbiol
; 18(3): 384-98, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26334669