Detalhe da pesquisa
1.
The Fitness Effects of Codon Composition of the Horizontally Transferred Antibiotic Resistance Genes Intensify at Sub-lethal Antibiotic Levels.
Mol Biol Evol
; 40(6)2023 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37221009
2.
Genetics' Piece of the PI: Inferring the Origin of Complex Traits and Diseases from Proteome-Wide Protein-Protein Interaction Dynamics.
Bioessays
; 42(2): e1900169, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31854021
3.
Avoidance of protein unfolding constrains protein stability in long-term evolution.
Biophys J
; 120(12): 2413-2424, 2021 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33932438
4.
Protein quality control acts on folding intermediates to shape the effects of mutations on organismal fitness.
Mol Cell
; 49(1): 133-44, 2013 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-23219534
5.
SodaPop: a forward simulation suite for the evolutionary dynamics of asexual populations on protein fitness landscapes.
Bioinformatics
; 35(20): 4053-4062, 2019 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30873519
6.
A functional substitution in the L-aromatic amino acid decarboxylase enzyme worsens somatic symptoms via a serotonergic pathway.
Ann Neurol
; 86(2): 168-180, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31177555
7.
Evolution on the Biophysical Fitness Landscape of an RNA Virus.
Mol Biol Evol
; 35(10): 2390-2400, 2018 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29955873
8.
Estimating the contribution of folding stability to nonspecific epistasis in protein evolution.
Proteins
; 86(12): 1242-1250, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30039542
9.
Protein Homeostasis Imposes a Barrier on Functional Integration of Horizontally Transferred Genes in Bacteria.
PLoS Genet
; 11(10): e1005612, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26484862
10.
Isolation and Analysis of Rare Norovirus Recombinants from Coinfected Mice Using Drop-Based Microfluidics.
J Virol
; 89(15): 7722-34, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25972549
11.
Minimalistic predictor of protein binding energy: contribution of solvation factor to protein binding.
Biophys J
; 108(4): 795-798, 2015 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25692584
12.
Contribution of selection for protein folding stability in shaping the patterns of polymorphisms in coding regions.
Mol Biol Evol
; 31(1): 165-76, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24124208
13.
Positively selected sites in cetacean myoglobins contribute to protein stability.
PLoS Comput Biol
; 9(3): e1002929, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23505347
14.
Highly abundant proteins favor more stable 3D structures in yeast.
Biophys J
; 104(3): L1-3, 2013 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-23442924
15.
The Streptomyces-produced antibiotic fosfomycin is a promiscuous substrate for archaeal isopentenyl phosphate kinase.
Biochemistry
; 51(4): 917-25, 2012 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-22148590
16.
A physical model reveals the mechanochemistry responsible for dynein's processive motion.
Biophys J
; 101(1): 144-50, 2011 Jul 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-21723824
17.
Phenylalanine-508 mediates a cytoplasmic-membrane domain contact in the CFTR 3D structure crucial to assembly and channel function.
Proc Natl Acad Sci U S A
; 105(9): 3256-61, 2008 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-18305154
18.
Mobile Gene Sequence Evolution within Individual Human Gut Microbiomes Is Better Explained by Gene-Specific Than Host-Specific Selective Pressures.
Genome Biol Evol
; 13(8)2021 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34132784
19.
A structural model of the pore-forming region of the skeletal muscle ryanodine receptor (RyR1).
PLoS Comput Biol
; 5(4): e1000367, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19390614
20.
Chromosomal barcoding of E. coli populations reveals lineage diversity dynamics at high resolution.
Nat Ecol Evol
; 4(3): 437-452, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32094541