Detalhe da pesquisa
1.
Chemo-/Regio-Selective Synthesis of Novel Functionalized Spiro[pyrrolidine-2,3'-oxindoles] under Microwave Irradiation and Their Anticancer Activity.
Molecules
; 28(18)2023 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37764279
2.
Novel Neplanocin A Derivatives as Selective Inhibitors of Hepatitis B Virus with a Unique Mechanism of Action.
Antimicrob Agents Chemother
; 66(6): e0207321, 2022 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35604213
3.
Pd-Catalysed [3 + 2]-cycloaddition towards the generation of bioactive bis-heterocycles/identification of COX-2 inhibitors via in silico analysis.
Org Biomol Chem
; 20(23): 4746-4752, 2022 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35612901
4.
Correction: Pd-Catalysed [3 + 2]-cycloaddition towards the generation of bioactive bis-heterocycles/identification of COX-2 inhibitors via in silico analysis.
Org Biomol Chem
; 20(46): 9241, 2022 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-36385579
5.
Synthesis and anti-HIV activity of a new isoxazole containing disubstituted 1,2,4-oxadiazoles analogs.
Bioorg Med Chem
; 56: 116612, 2022 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35026631
6.
Synthesis of 1,4-dihydropyrazolo[4,3-b]indoles via intramolecular C(sp2)-N bond formation involving nitrene insertion, DFT study and their anticancer assessment.
Bioorg Chem
; 114: 105114, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34243073
7.
E-pharmacophore guided discovery of pyrazolo[1,5-c]quinazolines as dual inhibitors of topoisomerase-I and histone deacetylase.
Bioorg Chem
; 94: 103409, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31732194
8.
Sequential Pd(0)/Fe(III) Catalyzed Azide-Isocyanide Coupling/Cyclization Reaction: One-Pot Synthesis of Aminotetrazoles.
J Org Chem
; 83(16): 9530-9537, 2018 Aug 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-30037227
9.
Iodine-catalyzed cross-coupling of isocyanides and thiols for the synthesis of S-thiocarbamates.
Org Biomol Chem
; 16(37): 8263-8266, 2018 09 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30206628
10.
Synthesis and anti-HBV activity of α-stereoisomer of aristeromycin based analogs.
Bioorg Med Chem Lett
; 26(16): 3945-9, 2016 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27426303
11.
The C-terminal calcium-sensitive disordered motifs regulate isoform-specific polymerization characteristics of calsequestrin.
Biopolymers
; 103(1): 15-22, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25091206
12.
Synthesis and anti-HCV determinant motif identification in pyranone carboxamide scaffold.
Bioorg Med Chem Lett
; 25(22): 5224-7, 2015 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26483202
13.
Vitamin D Receptor Antagonist MeTC7 Inhibits PD-L1.
Cancers (Basel)
; 15(13)2023 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37444542
14.
Structure based medicinal chemistry approach to develop 4-methyl-7-deazaadenine carbocyclic nucleosides as anti-HCV agent.
Bioorg Med Chem Lett
; 22(24): 7742-7, 2012 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23122860
15.
Structure based molecular design, synthesis and biological evaluation of α-pyrone analogs as anti-HSV agent.
Bioorg Med Chem Lett
; 22(19): 6261-6, 2012 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22921079
16.
Probing cationic selectivity of cardiac calsequestrin and its CPVT mutants.
Biochem J
; 435(2): 391-9, 2011 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21265816
17.
Structural Basis for the Understanding of Entry Inhibitors against SARS Viruses.
Curr Med Chem
; 29(4): 666-681, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-33992054
18.
Identification of a Vitamin-D Receptor Antagonist, MeTC7, which Inhibits the Growth of Xenograft and Transgenic Tumors In Vivo.
J Med Chem
; 65(8): 6039-6055, 2022 04 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35404047
19.
The catecholaminergic polymorphic ventricular tachycardia mutation R33Q disrupts the N-terminal structural motif that regulates reversible calsequestrin polymerization.
J Biol Chem
; 285(22): 17188-96, 2010 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-20353949
20.
Synthesis and antiviral activity of cyclopropyl-spirocarbocyclic adenosine, (4R,5S,6R,7R)-4-(6-amino-9H-purin-9-yl)-7-(hydroxymethyl)spiro[2.4]heptane-5,6-diol against hepatitis C virus.
Bioorg Med Chem Lett
; 21(13): 3982-5, 2011 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21621997