Detalhe da pesquisa
1.
Pharmacological Activation of Nrf2 Enhances Functional Liver Regeneration.
Hepatology
; 74(2): 973-986, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33872408
2.
Cellular Uptake of the Atypical Antipsychotic Clozapine Is a Carrier-Mediated Process.
Mol Pharm
; 15(8): 3557-3572, 2018 08 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29944835
3.
Innovative organotypic in vitro models for safety assessment: aligning with regulatory requirements and understanding models of the heart, skin, and liver as paradigms.
Arch Toxicol
; 92(2): 557-569, 2018 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-29362863
4.
A multicenter assessment of single-cell models aligned to standard measures of cell health for prediction of acute hepatotoxicity.
Arch Toxicol
; 91(3): 1385-1400, 2017 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-27344343
5.
Donor-Dependent and Other Nondefined Factors Have Greater Influence on the Hepatic Phenotype Than the Starting Cell Type in Induced Pluripotent Stem Cell Derived Hepatocyte-Like Cells.
Stem Cells Transl Med
; 6(5): 1321-1331, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28456008
6.
Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease.
Sci Rep
; 6: 25187, 2016 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27143246
7.
Comparative Proteomic Characterization of 4 Human Liver-Derived Single Cell Culture Models Reveals Significant Variation in the Capacity for Drug Disposition, Bioactivation, and Detoxication.
Toxicol Sci
; 147(2): 412-24, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26160117
8.
MicroRNA-122: a novel hepatocyte-enriched in vitro marker of drug-induced cellular toxicity.
Toxicol Sci
; 144(1): 173-85, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25527335
9.
Donor-Dependent and Other Nondefined Factors have Greater Influence on the Hepatic Phenotype than the Starting Cell Type in Induced Pluripotent Stem Cell Derived Hepatocyte-Like Cells.
Stem Cells Transl Med
; 6(8): 1751, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28749066