Detalhe da pesquisa
1.
Sequence selectivity of the cleavage sites induced by topoisomerase I inhibitors: a molecular dynamics study.
Nucleic Acids Res
; 41(22): 10010-9, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24021629
2.
A novel mechanism of XIAP degradation induced by timosaponin AIII in hepatocellular carcinoma.
Biochim Biophys Acta
; 1833(12): 2890-2899, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23906794
3.
Diastereoselective ruthenium porphyrin-catalyzed tandem nitrone formation/1,3-dipolar cycloaddition for isoxazolidines. Synthesis, in silico docking study and in vitro biological activities.
Org Biomol Chem
; 10(46): 9165-74, 2012 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-22964756
4.
Highly regio-, diastereo- and enantioselective one-pot gold/chiral Brønsted acid-catalysed cascade synthesis of bioactive diversely substituted tetrahydroquinolines.
Org Biomol Chem
; 10(35): 7208-19, 2012 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-22785458
5.
Anticancer auranofin engages 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) as a target.
Metallomics
; 11(11): 1925-1936, 2019 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31631207
6.
Proteomic and transcriptomic study on the action of a cytotoxic saponin (Polyphyllin D): induction of endoplasmic reticulum stress and mitochondria-mediated apoptotic pathways.
Proteomics
; 8(15): 3105-17, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18615425
7.
Persistence of camptothecin analog-topoisomerase I-DNA ternary complexes: a molecular dynamics study.
J Am Chem Soc
; 130(52): 17928-37, 2008 Dec 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-19035632
8.
Fluorophore-labeled beta-lactamase as a biosensor for beta-lactam antibiotics: a study of the biosensing process.
J Am Chem Soc
; 130(20): 6351-61, 2008 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-18429614
9.
Selective overexpression of human SIRT1 in adipose tissue enhances energy homeostasis and prevents the deterioration of insulin sensitivity with ageing in mice.
Am J Transl Res
; 5(4): 412-26, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23724165
10.
Akt blocks the tumor suppressor activity of LKB1 by promoting phosphorylation-dependent nuclear retention through 14-3-3 proteins.
Am J Transl Res
; 4(2): 175-86, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22611470
11.
Anticancer gold(I)-phosphine complexes as potent autophagy-inducing agents.
Chem Commun (Camb)
; 47(33): 9318-20, 2011 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-21584293
12.
Metal complexes in medicine with a focus on enzyme inhibition.
Curr Opin Chem Biol
; 14(2): 255-61, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20018553
13.
DNA binding and cytotoxicity of ruthenium(II) and rhenium(I) complexes of 2-amino-4-phenylamino-6-(2-pyridyl)-1,3,5-triazine.
Inorg Chem
; 46(3): 740-9, 2007 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-17257015
14.
Quantitative structure-activity (affinity) relationship (QSAR) study on protonation and cationization of alpha-amino acids.
J Phys Chem A
; 110(44): 12348-54, 2006 Nov 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-17078635
15.
Competition between pi and non-pi cation-binding sites in aromatic amino acids: a theoretical study of alkali metal cation (Li+, Na+, K+)-phenylalanine complexes.
Chemistry
; 10(8): 1966-76, 2004 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-15079836
16.
Experimental validation of theoretical potassium and sodium cation affinities of amides by mass spectrometric kinetic method measurements.
Rapid Commun Mass Spectrom
; 18(3): 345-55, 2004.
Artigo
em Inglês
| MEDLINE | ID: mdl-14755622
17.
Experimental validation of Gaussian-3 lithium cation affinities of amides: implications for the gas-phase lithium cation basicity scale.
Rapid Commun Mass Spectrom
; 16(3): 229-37, 2002.
Artigo
em Inglês
| MEDLINE | ID: mdl-11803545
18.
Absolute potassium cation affinities (PCAs) in the gas phase.
Chemistry
; 9(14): 3383-96, 2003 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-12866082