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2.
Br J Sports Med ; 49(12): 803-9, 2015 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-25833903

RESUMO

BACKGROUND: The identification of risk factors for groin injury in sport is important to develop and implement injury prevention strategies. OBJECTIVE: To identify and evaluate the evidence examining risk factors for groin injury in sport. MATERIAL AND METHODS: Nine electronic databases were systematically searched to June 2014. Studies selected met the following criteria: original data; analytic design; investigated a risk factor(s); included outcomes for groin injury sustained during sport participation. The Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines were followed and two independent authors assessed the quality and level of evidence with the Downs and Black (DB) criteria and Oxford Centre of Evidence-Based Medicine model, respectively. RESULTS: Of 2521 potentially relevant studies, 29 were included and scored. Heterogeneity in methodology and injury definition precluded meta-analyses. The most common risk factors investigated included age, hip range of motion, hip adductor strength and height. The median DB score across studies was 11/33 (range 6-20). The majority of studies represented level 2 evidence (cohort studies) however few considered the inter-relationships between risk factors. There is level 1 and 2 evidence that previous groin injury, higher-level of play, reduced hip adductor (absolute and relative to the hip abductors) strength and lower levels of sport-specific training are associated with increased risk of groin injury in sport. CONCLUSIONS: We recommended that investigators focus on developing and evaluating preparticipation screening and groin injury prevention programmes through high-quality randomised controlled trials targeting athletes at greater risk of injury.


Assuntos
Traumatismos em Atletas/etiologia , Virilha/lesões , Adolescente , Adulto , Fatores Etários , Traumatismos em Atletas/fisiopatologia , Métodos Epidemiológicos , Feminino , Humanos , Masculino , Força Muscular/fisiologia , Amplitude de Movimento Articular/fisiologia , Adulto Jovem
3.
Am J Speech Lang Pathol ; 32(4): 1644-1664, 2023 07 10.
Artigo em Inglês | MEDLINE | ID: mdl-37379208

RESUMO

PURPOSE: The aim of this study was to explore practicing speech-language pathologists' (SLPs') perceptions of factors that could facilitate or prevent the use of speech-generating devices (SGDs) in bilingual individuals with aphasia. Specifically, this exploratory study sought to identify the facilitators and barriers to SGD use in individuals with culturally and linguistically diverse backgrounds. METHOD: An online survey was distributed to SLPs through an e-mail listserv and social media of an augmentative and alternative communication company. This article focused on the results of the survey items related to (a) the presence of bilingual individuals with aphasia on an SLP's caseload, (b) training related to SGD or bilingual aphasia, and (c) barriers and facilitators to SGD use. A thematic analysis was conducted to analyze the barriers and facilitators to SGD use reported by the respondents. RESULTS: A total of 274 SLPs who met the inclusion criteria had experience in implementing SGD for people with aphasia. Regarding relevant training, our results indicated that very few SLPs received bilingual aphasia intervention training (17.22%) or bilingual SGD training (0.56%) in graduate school. The results from our thematic analysis revealed four major themes of barriers and facilitators to SGD use, including (a) hardware and software, (b) cultural and language content, (c) SLP's cultural and linguistic competency, and (d) resources. CONCLUSIONS: Practicing SLPs reported several barriers to SGD use in bilinguals with aphasia. Most notably, language barriers for monolingual SLPs were seen as the greatest barrier to language recovery in individuals with aphasia whose primary language is not English. Several other barriers were consistent with previous research, such as financial factors and insurance disparities. The top three most important factors that facilitate SGD use in bilinguals with aphasia, as identified by the respondents, include user-friendly symbol organization, personalized words, and ease of programming.


Assuntos
Afasia , Transtornos da Comunicação , Patologia da Fala e Linguagem , Humanos , Fala , Idioma , Barreiras de Comunicação , Inquéritos e Questionários
4.
Knee ; 39: 29-37, 2022 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-36115180

RESUMO

BACKGROUND: Anterior cruciate ligament (ACL) injury and subsequent reconstruction is common and has a profound effect on health-related quality of life. There is currently limited understanding as to which variables are associated with a successful outcome post-ACL reconstruction (ACLR) in recreational athletes. PURPOSE: Explore the association between both patient-reported and performance-based measures, and successful outcome, post-ACLR in recreational athletes. PROCEDURES: We sought to recruit recreational athletes within one month of a primary-ACLR for a prospective cohort study. A dichotomised patient specific functional scale of ≥9 points determined a successful outcome at nine-months post-operative. Secondary patient-reported and performance-based data were collected at baseline, three-, six-, and nine-months post-operative. The association between secondary data and the primary outcome was determined using binomial logistic regression, expressed using odds ratio (OR) and 95% confidence intervals (CI). MAIN RESULTS: 90 participants were recruited (males: 58, females: 32, mean age 32.8 years [±7.9], mean height 173.5 [±10.0], mean body mass 74.0 kg [±15.8]), 87 consented to baseline measures. 47 participants completed full data collection and 21 (45%) reported a successful outcome. Higher knee osteoarthritis outcome score (OR range 1.07-1.12) and anterior cruciate ligament quality of life (ACL-QoL) scores (OR range 1.06-1.10) were associated with a successful outcome post-ACLR at various timepoints. CONCLUSIONS: Patient-reported, rather than performance-based, measures were associated with successful outcome nine-months post-ACLR in recreational athletes. Both patient-reported and performance-based characteristics are advocated to guide optimal return to function in clinical practice.


Assuntos
Lesões do Ligamento Cruzado Anterior , Reconstrução do Ligamento Cruzado Anterior , Masculino , Feminino , Humanos , Adulto , Qualidade de Vida , Volta ao Esporte , Estudos Prospectivos , Lesões do Ligamento Cruzado Anterior/cirurgia , Atletas
5.
Surgeon ; 9(5): 284-91, 2011 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-21843824

RESUMO

We review the available literature on the use of motion analysis as an outcome measure following total hip arthroplasty. Several studies have investigated spatio-temporal parameters of gait, kinematics, kinetics and electromyographic outputs following hip arthroplasty. We undertook to review all these studies to evaluate the value of motion analysis as an outcome measure. The search of the literature yielded eight studies. Motion analysis demonstrates functional improvement in patients post-operatively, but the values of the variables measured do not reach the same levels as control subjects. Motion analysis does not show much difference post-operatively between patients operated on by different technique or incision. Furthermore, motion analysis can identify subtle functional limitations which may not be detectable with conventional outcome measures.


Assuntos
Artroplastia de Quadril , Articulação do Quadril/fisiopatologia , Destreza Motora , Fenômenos Biomecânicos , Articulação do Quadril/cirurgia , Humanos , Movimento (Física) , Avaliação de Resultados em Cuidados de Saúde , Amplitude de Movimento Articular
6.
Sports Med ; 46(12): 1847-1867, 2016 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-27142535

RESUMO

BACKGROUND: Sports-related groin pain (SRGP) is a common entity in rotational sports such as football, rugby and hockey, accounting for 12-18 % of injuries each year, with high recurrence rates and often prolonged time away from sport. OBJECTIVE: This systematic review synthesises movement and muscle function findings to better understand deficits and guide rehabilitation. STUDY SELECTION: Prospective and retrospective cross-sectional studies investigating muscle strength, flexibility, cross-sectional area, electromyographic activation onset and magnitude in patients with SRGP were included. SEARCH METHODS: Four databases (MEDLINE, Web of Knowledge, EBSCOhost and EMBASE) were searched in June 2014. Studies were critiqued using a modified version of the Downs and Black Quality Index, and a meta-analysis was performed. RESULTS: Seventeen studies (14 high quality, 3 low quality; 8 prospective and 9 retrospective) were identified. Prospective findings: moderate evidence indicated decreased hip abduction flexibility as a risk factor for SRGP. Limited or very limited evidence suggested that decreased hip adduction strength during isokinetic testing at ~119°/s was a risk factor for SRGP, but no associations were found at ~30°/s or ~210°/s, or with peak torque angle. Decreased hip abductor strength in angular velocity in ~30°/s but not in ~119°/s and ~210°/s was found as a risk factor for SRGP. No relationships were found with hip internal or external rotation range of movement, nor isokinetic knee extension strength. Decreased isokinetic knee flexion strength also was a potential risk factor for SRGP, at a speed ~60°/s. Retrospective findings: there was strong evidence of decreased hip adductor muscle strength during a squeeze test at 45°, and decreased total hip external rotation range of movement (sum of both legs) being associated with SRGP. There was strong evidence of no relationship to abductor muscle strength nor unilateral hip internal and external rotation range of movement. Moderate evidence suggested that increased abduction flexibility and no change in total hip internal rotation range of movement (sum of both legs) were retrospectively associated with SRGP. Limited or very limited evidence (significant findings only) indicated decreased hip adductor muscle strength during 0° and 30° squeeze tests and during an eccentric hip adduction test, but a decrease in the isometric adductors-to-abductors strength ratio at speed 120°/s; decreased abductors-to-adductors activation ratio in the early phase in the moving leg as well as in all three phases in the weight-bearing leg during standing hip flexion; and increased hip flexors strength during isokinetic and decrease in transversus abdominis muscle resting thickness associated with SRGP. CONCLUSIONS: There were a number of significant movement and muscle function associations observed in athletes both prior to and following the onset of SRGP. The strength of findings was hampered by the lack of consistent terminology and diagnostic criteria, with there being clear guides for future research. Nonetheless, these findings should be considered in rehabilitation and prevention planning.


Assuntos
Dor Abdominal/etiologia , Virilha , Articulação do Quadril/fisiologia , Músculo Esquelético/fisiologia , Dor/fisiopatologia , Dor Abdominal/fisiopatologia , Artralgia , Virilha/lesões , Humanos , Amplitude de Movimento Articular
7.
Man Ther ; 17(2): 145-9, 2012 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-22306511

RESUMO

BACKGROUND: Groin pain arising from adductor muscle injury is common amongst football code athletes and can result in significant time lost from sporting participation. The associated motor control deficits are not well understood. AIMS: The aim of this study was to better understand the coronal plane muscle activation patterns associated with chronic adductor injury. METHODOLOGY: Measures of muscle activation at various stages of the standing hip flexion manoeuvre were made with surface electromyography and motion capture in 9 male football code subjects with chronic adductor injury, and 9 matched controls. RESULTS: The gluteus medius to adductor longus activation ratio was significantly reduced in subjects with groin pain when the injured leg was either moving (F = 64.3, p < 0.001) or in stance phase (F = 32.4, p < 0.001) when compared to activity-matched uninjured subjects, equating to a difference varying between 20 and 40% depending on phase of movement. These differences were particularly due to decreased abductor muscle activation. No significant differences between the uninjured and injured side of patients was found. CONCLUSION: Football code athletes with groin pain exhibit significantly altered coronal plane muscle activation with comparison to uninjured subjects. These findings need to be taken into account when planning rehabilitation for these athletes.


Assuntos
Traumatismos em Atletas/fisiopatologia , Futebol Americano/lesões , Virilha/lesões , Virilha/fisiopatologia , Força Muscular/fisiologia , Músculo Esquelético/lesões , Músculo Esquelético/fisiopatologia , Entorses e Distensões/fisiopatologia , Adulto , Fenômenos Biomecânicos , Estudos de Casos e Controles , Doença Crônica , Eletromiografia , Humanos , Masculino , Medição da Dor
8.
Neurobiol Dis ; 19(3): 400-6, 2005 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-16023582

RESUMO

The processing of the amyloid precursor protein (APP) by the secretase family of protease enzymes can be influenced by a variety of diverse factors, including elements of the immune response. In this study, we have investigated the effect of the pro-inflammatory lipopolysaccharide (LPS) on APP processing in rat glial cell cultures derived from both cortex and cerebellum. LPS activation of the cells, as monitored by the induction of the pro-inflammatory nitric oxide synthase (iNOS) enzyme, elicited no change in the overall cellular expression levels of APP, although there was a marked concentration-related increase in the secretion of the soluble APPs following both short- (4 h) and long-term (18 h) drug treatment times. The stimulation of APPs secretion was blocked by the protein kinase C (PKC) inhibitor GF109203x, suggesting that LPS may act via a PKC-mediated pathway to increase APPs secretion.


Assuntos
Precursor de Proteína beta-Amiloide/metabolismo , Lipopolissacarídeos/farmacologia , Neuroglia/efeitos dos fármacos , Proteína Quinase C/efeitos dos fármacos , Proteína Quinase C/metabolismo , Animais , Cerebelo/efeitos dos fármacos , Córtex Cerebral/efeitos dos fármacos , Relação Dose-Resposta a Droga , Immunoblotting , Indóis/farmacologia , Maleimidas/farmacologia , Neuroglia/metabolismo , Óxido Nítrico Sintase/efeitos dos fármacos , Óxido Nítrico Sintase/metabolismo , Óxido Nítrico Sintase Tipo II , Inibidores de Proteínas Quinases/farmacologia , Ratos , Ratos Wistar , Fatores de Tempo
9.
Neurobiol Dis ; 17(1): 70-6, 2004 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-15350967

RESUMO

The inducible form of nitric oxide synthase (iNOS) is an essential element of the immune response, which is expressed primarily in microglial cells within the CNS. Exposure of rat cortical neuronal cells to the pro-inflammatory bacterial endotoxin lipopolysaccharide (LPS) resulted in a significant increase in the expression of the cellular iNOS protein expression and NO generation (which serves as an indirect measure of NOS catalytic activity). These effects were potentiated by costimulation with interferon-gamma (IFNgamma) and the increase in NO generation was abolished by the iNOS selective inhibitor 1400W, although this did not attenuate the toxin-induced increase in the enzyme expression. As the cortex is one of the principal areas to be targeted in Alzheimer's disease (AD), the present findings may help to further our understanding of the biochemical events associated with the neurodegenerative process.


Assuntos
Córtex Cerebral/enzimologia , Regulação Enzimológica da Expressão Gênica/fisiologia , Neurônios/enzimologia , Óxido Nítrico Sintase/biossíntese , Animais , Células Cultivadas , Córtex Cerebral/efeitos dos fármacos , Regulação Enzimológica da Expressão Gênica/efeitos dos fármacos , Lipopolissacarídeos/farmacologia , Neurônios/efeitos dos fármacos , Óxido Nítrico/biossíntese , Óxido Nítrico/genética , Óxido Nítrico Sintase/genética , Óxido Nítrico Sintase Tipo II , Ratos
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