Detalhe da pesquisa
1.
Nonmetastatic, Castration-Resistant Prostate Cancer and Survival with Darolutamide.
N Engl J Med
; 383(11): 1040-1049, 2020 09 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32905676
2.
Darolutamide in Nonmetastatic, Castration-Resistant Prostate Cancer.
N Engl J Med
; 380(13): 1235-1246, 2019 03 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30763142
3.
Efficacy and safety of darolutamide in Japanese patients with nonmetastatic castration-resistant prostate cancer: a sub-group analysis of the phase III ARAMIS trial.
Int J Clin Oncol
; 26(3): 578-590, 2021 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-33226524
4.
First-in-human Phase 1 open label study of the BET inhibitor ODM-207 in patients with selected solid tumours.
Br J Cancer
; 123(12): 1730-1736, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32989226
5.
Prediction and impact of attacks of Raynaud's phenomenon, as judged by patient perception.
Rheumatology (Oxford)
; 54(8): 1443-7, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25752312
6.
A double-blind, randomized, placebo-controlled crossover trial of the α2C-adrenoceptor antagonist ORM-12741 for prevention of cold-induced vasospasm in patients with systemic sclerosis.
Rheumatology (Oxford)
; 53(5): 948-52, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24489014
7.
A polymorphism in the protein kinase C gene PRKCB is associated with α2-adrenoceptor-mediated vasoconstriction.
Pharmacogenet Genomics
; 23(3): 127-134, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23337848
8.
The effects of sympathectomy on finger photoplethysmography and temperature measurements in healthy subjects.
Anesth Analg
; 113(1): 78-83, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21519049
9.
Darolutamide and health-related quality of life in patients with non-metastatic castration-resistant prostate cancer: An analysis of the phase III ARAMIS trial.
Eur J Cancer
; 154: 138-146, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34273811
10.
Pharmacokinetics, Antitumor Activity, and Safety of ODM-201 in Patients with Chemotherapy-naive Metastatic Castration-resistant Prostate Cancer: An Open-label Phase 1 Study.
Eur Urol
; 69(5): 834-40, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26463318
11.
Variation in the alpha2B-adrenoceptor gene as a risk factor for prehospital fatal myocardial infarction and sudden cardiac death.
J Am Coll Cardiol
; 41(2): 190-4, 2003 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12535806
12.
Cloning, characterisation and identification of several polymorphisms in the promoter region of the human alpha2B-adrenergic receptor gene.
Biochem Pharmacol
; 67(3): 469-78, 2004 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15037199
13.
The insertion/deletion variation in the alpha2B-adrenoceptor does not seem to modify the risk for acute myocardial infarction, but may modify the risk for hypertension in sib-pairs from families with type 2 diabetes.
Cardiovasc Diabetol
; 2: 15, 2003 Nov 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-14633283
14.
Dorsal hand vein responses to the α1-adrenoceptor agonist phenylephrine do not predict responses to the α2-adrenoceptor agonist dexmedetomidine.
Eur J Pharmacol
; 653(1-3): 70-4, 2011 Feb 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-21147097
15.
Prospective-retrospective biomarker analysis for regulatory consideration: white paper from the industry pharmacogenomics working group.
Pharmacogenomics
; 12(7): 939-51, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21787188
16.
Identification of a novel 12-nucleotide insertion polymorphism in the promoter region of ADRA2B: full linkage with the 9-nucleotide deletion in the coding region and influence on transcriptional activity.
Biochem Pharmacol
; 79(3): 407-12, 2010 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19728989
17.
Estimation of cardiac output in a pharmacological trial using a simple method based on arterial blood pressure signal waveform: a comparison with pulmonary thermodilution and echocardiographic methods.
Eur J Clin Pharmacol
; 62(6): 401-7, 2006 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-16570186
18.
Effects of low and high plasma concentrations of dexmedetomidine on myocardial perfusion and cardiac function in healthy male subjects.
Anesthesiology
; 105(5): 902-10; quiz 1069-70, 2006 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-17065883
19.
Determinants of coronary flow velocity reserve in healthy young men.
Am J Physiol Heart Circ Physiol
; 291(2): H564-9, 2006 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-16501023
20.
Effect of alpha2B-adrenoceptor polymorphism on peripheral vasoconstriction in healthy volunteers.
Anesthesiology
; 102(3): 536-42, 2005 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-15731590