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1.
World J Urol ; 42(1): 145, 2024 Mar 13.
Artigo em Inglês | MEDLINE | ID: mdl-38478094

RESUMO

INTRODUCTION AND OBJECTIVES: Medical device companies have introduced new TFL machines, including Soltive (Olympus, Japan), Fiber Dust (Quanta System, Italy), and TFLDrive (Coloplast, France). The primary objective of this study is to compare our initial clinical experiences with TFL using those devices. Through this historical comparison of Thulium Fiber Laser systems for stone lithotripsy, we aim to advance our understanding and approach toward achieving safe and effective TFL parameters. MATERIALS AND METHODS: The data for this comparative analysis were extracted from three distinct prospective series that were previously published, outlining our initial clinical experience with the Soltive (Olympus, Japan), FiberDust laser (Quanta System, Italy), and TFLDrive laser (Coloplast, France). Parameters such as stone size, stone density, laser-on time (LOT), and laser settings were meticulously recorded. Additionally, we assessed critical variables such as ablation speed (expressed in mm3/s) and Joules/mm3 for each lithotripsy procedure. RESULTS: A total of 149 patients were enrolled in this study. Among them, 120 patients were subjected to analysis concerning renal stones. Statistically significant differences were observed in the median (IQR) stone volume: 650 (127-6027) mm3 for TFLDrive, 1800 (682.8-2760) mm3 for Soltive, and 1125 (294-4000) mm3 for FiberDust (p: 0.007); while there were no differences regarding stone density among the groups. Significant variations were identified in median (IQR) pulse energy, frequency, and total power. The Soltive group exhibited lower energy levels (0.3 J vs. 0.6 J, p: 0.002) but significantly higher pulse frequency (100 Hz vs. 17.5 Hz, p: 0.003) and total power (24 W vs. 11W, p: 0.001) compared to the other groups. Laser-on time showed no substantial differences across all three groups. Additionally, a statistically significant difference was observed in median J/mm3, with the TFLDrive group using higher values (24 J/mm3, p: 0.001), while the Soltive group demonstrated a higher median ablation speed of 1.16 mm3/s (p: 0.001). The overall complication rate remained low for all groups, with comparable stone-free rates. CONCLUSION: By reducing pulsed frequency, we improved laser efficiency, but smaller volumes lead to decreased efficiency due to increased retropulsion and fragment movement. Further studies are needed to identify and establish the appropriate laser settings for this new technology.


Assuntos
Cálculos Renais , Lasers de Estado Sólido , Litotripsia a Laser , Litotripsia , Humanos , Túlio/uso terapêutico , Litotripsia a Laser/métodos , Cálculos Renais/cirurgia
2.
World J Urol ; 42(1): 57, 2024 Jan 27.
Artigo em Inglês | MEDLINE | ID: mdl-38280001

RESUMO

INTRODUCTION: Both Holmium:yttrium-aluminium-garnet (Ho:YAG) laser and Thulium Fiber Laser (TFL) can effectively treat all urinary stone types. This in vitro study evaluated the ablation volume per pulse (AVP) and required energy needed to ablate 1mm3 (RE, J/mm3) of various stone types at different laser settings with TFL. METHODS: 272-µm core-diameter laser fibers (Boston Scientific©) were connected to a 50 Watts TFL generator (IPG®). An experimental setup immerged human stones of calcium oxalate monohydrate (COM), uric acid (UA), and cystine (CYS) with a single pulse lasing emission (0.5/0.8/1 J), in contact mode. Stones were dried out before three-dimensional scanning to measure AVP and deduce from the pulse energy (PE) and AVP the RE. A direct comparison with known Ho:YAG's AVP and RE was then carried out. RESULTS: AVP for COM stones was significantly greater than those for CYS stones and similar to UA stones (p = 0.02 and p = 0.06, respectively). If AVP increased with PE against COM and UA stones, AVP decreased against CYS stones. 1 J PE resulted in a threefold lower RE compared with other PE for COM stones. On the contrary, RE for CYS increased with PE, whereas PE did not had influence on RE for UA. TFL was associated with greater AVP for COM, but lower for UA and CYS stones compared to Ho:YAG laser. CONCLUSION: This in vitro study firstly describes the ablation volume per pulse and required energy to treat a cubic millimeter of three frequent human stone types, and suggest TFL could not be suited for cystine. Therefore, stone composition could be considered when choosing the laser source for lithotripsy.


Assuntos
Terapia a Laser , Lasers de Estado Sólido , Litotripsia a Laser , Nefrolitíase , Cálculos Urinários , Humanos , Litotripsia a Laser/métodos , Túlio , Cistina , Cálculos Urinários/cirurgia , Lasers de Estado Sólido/uso terapêutico , Hólmio
3.
World J Urol ; 42(1): 233, 2024 Apr 13.
Artigo em Inglês | MEDLINE | ID: mdl-38613608

RESUMO

PURPOSE: This study aimed to evaluate the ability of Kidney Stone Calculator (KSC), a flexible ureteroscopy surgical planning software, to predict the lithotripsy duration with both holmium:YAG (Ho:YAG) and thulium fiber laser (TFL). METHODS: A multicenter prospective study was conducted from January 2020 to April 2023. Patients with kidney or ureteral stones confirmed at non-contrast computed tomography and treated by flexible ureteroscopy with laser lithotripsy were enrolled. "Kidney Stone Calculator" provided stone volume and subsequent lithotripsy duration estimation using three-dimensional segmentation of the stone on computed tomography and the graphical user interface for laser settings. The primary endpoint was the quantitative and qualitative comparison between estimated and effective lithotripsy durations. Secondary endpoints included subgroup analysis (Ho:YAG-TFL) of differences between estimated and effective lithotripsy durations and intraoperative outcomes. Multivariate analysis assessed the association between pre- and intraoperative variables and these differences according to laser source. RESULTS: 89 patients were included in this study, 43 and 46 in Ho:YAG and TFL groups, respectively. No significant difference was found between estimated and effective lithotripsy durations (27.37 vs 28.36 min, p = 0.43) with a significant correlation (r = + 0.89, p < 0.001). Among groups, this difference did not differ (p = 0.68 and 0.07, respectively), with a higher correlation between estimated and effective lithotripsy durations for TFL compared to Ho:YAG (r = + 0.95, p < 0.001 vs r = + 0.81, p < 0.001, respectively). At multivariate analysis, the difference was correlated with preoperative (volume > 2000 mm3 (Ho:YAG), 500-750 mm3 SV and calyceal diverticulum (TFL)), operative (fragmentation setting (p > 0.001), and basket utilization (p = 0.05) (Ho:YAG)) variables. CONCLUSION: KSC is a reliable tool for predicting the lithotripsy duration estimation during flexible ureteroscopy for both Ho:YAG and TFL. However, some variables not including laser source may lead to underestimating this estimation.


Assuntos
Cálculos Renais , Litotripsia , Cálculos Ureterais , Humanos , Hólmio , Túlio , Ureteroscopia , Estudos Prospectivos , Cálculos Renais/cirurgia , Lasers
4.
World J Urol ; 42(1): 362, 2024 May 30.
Artigo em Inglês | MEDLINE | ID: mdl-38814457

RESUMO

OBJECTIVE: To evaluate long-term surgical and functional outcomes of cystinuric patients exclusively treated with Ureteroscopy (URS). METHODS: Data from patients treated for cystine stones at a single academic center were retrospectively analyzed. The management protocol consisted of (i) treating symptomatic or > 7 mm stones, (ii) multi-staged URS for voluminous stones, (iii) referring patients to a dedicated nephrological clinic. The eGFR was calculated according to the MDRD formula. CKD category was assessed according to the NKF classification. Relevant CKD was defined as CKD category ≥ 3a. Descriptive statistics were used to analyze the cohort data. RESULTS: Data from 46 cystinuric patients treated with 332 URS were available. Median age at diagnosis and at first URS in our center were 18 and 32 years, respectively. Median follow-up was 101 months. Median number of URS and recurrences per patient were 6 and 2, respectively. The median interval between the first and the last available creatinine level was 64 months. Median first and last eGFR were 72 and 74 mL/min, respectively. Overall, 83% of patients had stable or improved renal function within the study period. Ureteral stricture occurred in 3 (6.5%) patients. CONCLUSIONS: Cystinuria requires intensive endoscopic management. Most patients treated with URS have stable or improved renal function within a long-term follow-up. CKD is a not neglectable event that potentially occurs at an early stage of life. Current findings should be considered for the surgical management of cystinuric patients.


Assuntos
Cistinúria , Centros de Atenção Terciária , Ureteroscopia , Humanos , Masculino , Estudos Retrospectivos , Adulto , Feminino , Adolescente , Cistinúria/complicações , Adulto Jovem , Resultado do Tratamento , Fatores de Tempo , Cálculos Renais/cirurgia , Pessoa de Meia-Idade , Criança
5.
World J Urol ; 41(10): 2627-2636, 2023 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-37468656

RESUMO

BACKGROUND: The management of urolithiasis has undergone significant advancements with the introduction of pulsed lasers, particularly the holmium:yttrium-aluminum-garnet (Ho:YAG) laser, which is currently considered the gold standard in endourology. However, the Ho:YAG laser has certain limitations, such as the inability to support small laser fibers (150 µm) and the requirement of a heavy water cooling system, making it challenging to transfer between operating rooms. These limitations have led to the emergence of new laser technologies, including the thulium fiber laser (TFL) and the thulium:yttrium-aluminum-garnet laser (Tm:YAG), as potential alternatives to the Ho:YAG laser. METHODS: In this review, we aimed to evaluate the effectiveness and safety of TFL, Ho:YAG, and Tm:YAG lasers in real-life scenarios by comparing clinical trial data with laboratory findings. A literature review was conducted, and relevant in vitro studies and clinical trials until March 2023 were analyzed. RESULTS: The findings indicate that TFL has demonstrated high ablation efficiency for stones of any composition, size, and location, superior the capabilities of Ho:YAG lasers. TFL has shown superior dusting and fragmentation abilities, lower retropulsion, and increased patient safety. The laser parameters, such as ablation efficiency, speed, operative time, dust quality, retropulsion, visibility, temperature safety, and stone-free rate, were compared between laboratory studies and clinical outcomes. CONCLUSION: Although the number of studies on TFL is limited, the available evidence suggests that TFL represents a significant advancement in laser technology for lithotripsy. However, further research is needed to fully explore the implications and limitations of TFL and Tm:YAG lasers.


Assuntos
Lasers de Estado Sólido , Litotripsia a Laser , Urolitíase , Humanos , Lasers de Estado Sólido/uso terapêutico , Túlio/uso terapêutico , Hólmio , Urolitíase/cirurgia
6.
World J Urol ; 41(12): 3765-3771, 2023 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-37833547

RESUMO

BACKGROUND AND OBJECTIVE: We aimed to evaluate the concordance between the pre-settings ranges of thulium fibre laser (TFL) (Coloplast TFL Drive, Denmark) with easy-to-use graphical user interface and the laser settings used by a high-volume endo-urologist during surgical procedures. MATERIALS AND METHODS: In October 2022, we prospectively collected data of 67 patients who underwent TFL Drive (Coloplast, Denmark) for the management of urinary stones. Urothelial tumour (upper tract urinary cancer (UTUC) and bladder) 200 and 150 µm laser fibres were used for procedures. Stones characteristics (size and density) tumours and stenosis localizations, laser-on time (LOT), and laser settings were recorded. We also assessed the ablation speed (mm3/s), laser power (W), and Joules/mm3 values for each lithotripsy. RESULTS: A total 67 patients took part in the study. Median age was 52 (15-81) years. 55 (82%), 8 (12%), and 4 (6%) patients presented urinary stones, urothelial tumour, and stenosis, respectively. Median stone volume was 438 (36-6027) mm3 and median density was 988 (376-2000) HU. Median pulse energy was 0.6 (0.3-1.2), 0.8 (0.5-1) and 1 J for urinary stones, urothelial tumour and stenosis respectably. Endoscopically stone-free rate was 89%. Graphical user interface and surgeon accordance with the safety range were observed in 93.2%, 100% and 100% for urinary stones, UTUC and stenosis, respectively. CONCLUSION: During endoscopic procedures for urinary stones treatment, it is frequently needed to change laser parameters. These new TFL and GUI technology parameters remained in the pre-set security range in 94.1% of procedures.


Assuntos
Lasers de Estado Sólido , Litotripsia a Laser , Neoplasias , Cálculos Urinários , Humanos , Pessoa de Meia-Idade , Túlio , Litotripsia a Laser/métodos , Constrição Patológica , Cálculos Urinários/cirurgia , Lasers de Estado Sólido/uso terapêutico
7.
World J Urol ; 41(8): 2119-2125, 2023 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-37414942

RESUMO

INTRODUCTION: Holmium:yttrium-aluminium-garnet (Ho:YAG) and thulium fiber (TFL) lasers are currently the two laser sources recommended for endocorporeal laser lithotripsy (ELL). Recently, the pulsed-thulium:YAG (Tm:YAG) laser was also proposed for ELL, as an answer to both Ho:YAG and TFL limitations. We aimed to evaluate the efficiency, safety, and laser settings of Tm:YAG laser in ELL during retrograde intrarenal surgery (RIRS). METHODS: A prospective study of the first 25 patients with ureteral and renal stones who underwent RIRS using the Thulio (pulsed-Tm:YAG, Dornier©, Germany) was performed in a single center. 272 µm laser fibers were used. Stone size, stone density, laser-on time (LOT) and laser settings were recorded. We also assessed the ablation speed (mm3/s), Joules/mm3 and laser power (W) values for each procedure. Postoperative results, such as stone-free rate (SFR) and zero fragments rate (ZFR) were also recorded. RESULTS: A total of 25 patients were analyzed (Table 1). The median (IQR) age was 55 (44-72) years old. Median (IQR) stone volume was 2849 (916-9153)mm3. Median (IQR) stone density was 1000 (600-1174)HU. Median (IQR) pulse energy, pulse rate and total power were 0.6 (0.6-0,8)J, 15(15-20)Hz and 12(9-16)W, respectively. All procedures used "Captive Fragmenting" pulse modulation (Table 2). The median (IQR) J/mm3 was 14,8 (6-21). The median (IQR) ablation rate was 0,75 (0,46-2)mm3/s. One postoperative complications occurred (streinstrasse). SFR and ZFR were 95% and 55%, respectively. CONCLUSION: The pulsed-Tm:YAG laser is a safe and effective laser source for lithotripsy during RIRS, using low pulse energy and low pulse frequency.


Assuntos
Cálculos Renais , Lasers de Estado Sólido , Litotripsia a Laser , Humanos , Pessoa de Meia-Idade , Idoso , Lasers de Estado Sólido/uso terapêutico , Túlio/uso terapêutico , Estudos Prospectivos , Litotripsia a Laser/métodos , Cálculos Renais/cirurgia , Hólmio
8.
World J Urol ; 41(12): 3437-3447, 2023 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-37932561

RESUMO

PURPOSE: To provide a technological description of the new pulsed solid-state Thulium:YAG laser (Tm:YAG). In addition, current available literature on Tm:YAG lithotripsy is also reviewed. MATERIALS AND METHODS: Medline, Scopus, Embase, and Web of Science databases were used to search for Tm:YAG operating mode articles. RESULTS: Tm:YAG technology works with a laser cavity with thulium-doped YAG crystal, pumped by laser diodes. Laser beam operates at 2013 nm, with an adjustable peak power (≥ 1000 W) and the minimal fiber laser diameter is of 200 µm. It has an intermediate water absorption coefficient and peak power-pulse duration. Various pulse modulations are proposed, aiming to minimize stone retropulsion. Multiple comparative in vitro studies suggest that Tm:YAG's ability to fragment stones is similar to the one of the Ho:YAG laser; on the contrary, its ability to dust all stone types is similar to the one of the TFL, with a low retropulsion. A single in vivo study assessed Tm:YAG lithotripsy feasibility. CONCLUSIONS: The new pulsed solid-state thulium:YAG laser could represent a safe and effective compromise between Ho:YAG laser and TFL for endoscopic lithotripsy, either in retrograde intra-renal surgeries or in percutaneous nephrolithotomy.


Assuntos
Lasers de Estado Sólido , Litotripsia a Laser , Litotripsia , Humanos , Lasers de Estado Sólido/uso terapêutico , Túlio , Hólmio
12.
J Endourol ; 2024 Jul 03.
Artigo em Inglês | MEDLINE | ID: mdl-38874270

RESUMO

Background: Among emerging AI technologies, Chat-Generative Pre-Trained Transformer (ChatGPT) emerges as a notable language model, uniquely developed through artificial intelligence research. Its proven versatility across various domains, from language translation to healthcare data processing, underscores its promise within medical documentation, diagnostics, research, and education. The current comprehensive review aimed to investigate the utility of ChatGPT in urology education and practice and to highlight its potential limitations. Methods: The authors conducted a comprehensive literature review of the use of ChatGPT and its applications in urology education, research, and practice. Through a systematic review of the literature, with a search strategy using databases, such as PubMed and Embase, we analyzed the advantages and limitations of using ChatGPT in urology and evaluated its potential impact. Results: A total of 78 records were eligible for inclusion. The benefits of ChatGPT were frequently cited across various contexts. In educational/academic benefits mentioned in 21 records (87.5%), ChatGPT showed the ability to assist urologists by offering precise information and responding to inquiries derived from patient data analysis, thereby supporting decision making; in 18 records (75%), advantages comprised personalized medicine, predictive capabilities for disease risks and outcomes, streamlining clinical workflows and improved diagnostics. Nevertheless, apprehensions were expressed regarding potential misinformation, underscoring the necessity for human supervision to guarantee patient safety and address ethical concerns. Conclusion: The potential applications of ChatGPT hold the capacity to bring about transformative changes in urology education, research, and practice. AI technology can serve as a useful tool to augment human intelligence; however, it is essential to use it in a responsible and ethical manner.

13.
J Endourol ; 38(5): 488-498, 2024 May.
Artigo em Inglês | MEDLINE | ID: mdl-38429915

RESUMO

Urothelial carcinoma (UC) affecting the urinary tract is recognized as one of the prevalent types of cancer, ranking fifth in terms of incidence. However, it is important to note that upper tract urothelial carcinoma (UTUC), in comparison to bladder cancer, is relatively uncommon and represents a minority of UC cases, accounting for ∼5% to 10%. It is worth emphasizing that as much as 60% of UTUC cases are invasive at the time of diagnosis, in contrast to 25% of bladder cancer cases. These statistics highlight the urgent need for well-designed, multidisciplinary strategies to guide optimal management for this vulnerable patient population, aiming to control treatment variability and minimize the risks associated with undertreatment and overtreatment. Methods: In this study, we present a comparative analysis of the contemporary guidelines on UTUC management from the European Association of Urology (EAU) and the American Urological Association/Society of Urologic Oncology (AUA/SUO) released in 2023. Our objective is to contrast the different guidelines and examine the evidence on which their recommendations are based. Results: By thoroughly reviewing the guidelines from both organizations, we observed substantial agreement on the management of UTUC. However, we also identified noticeable differences among these guidelines, leading to a wide range of recommendations. These disparities might stem from variations in clinical practices, regional preferences, and the availability of resources. It is crucial to acknowledge that both the EAU and AUA/SUO base their guidelines on the latest scientific evidence and expert consensus within their respective regions. Conclusions: These findings underscore the importance of ongoing collaboration, knowledge exchange, and harmonization of guidelines to improve the standard of care for UTUC globally. Future research should focus on identifying areas of consensus and bridging the gaps between different international guidelines to enhance the management outcomes for this challenging disease.


Assuntos
Guias de Prática Clínica como Assunto , Humanos , Europa (Continente) , Estados Unidos , Carcinoma de Células de Transição/terapia , Carcinoma de Células de Transição/diagnóstico , Carcinoma de Células de Transição/patologia , Neoplasias Urológicas/terapia
14.
Fr J Urol ; 34(7-8): 102644, 2024 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-38759842

RESUMO

OBJECTIVES: To characterize and compare in vitro the surfaces of ureteral stents (STENTS) before utilization. METHODS: Our in vitro experiment included six unused STENTS models: three double-pigtail with side orifices (ImaJin and Stenostent [Coloplast©,France], TriaSoft [BostonScientific©,USA]), two double-pigtail without side orifice (Vortek-TumorStent [Coloplast©,France], Urosoft-TumorStent [Bard-Angiomed©,Germany]) and one single-pigtail (J-Fil [Rocamed©,Monaco]). STENTS were made of polyurethane except for ImaJin (silicone). For all STENTS, four parts of the stent were specifically analyzed under high-resolution scanning electron microscopy (HR-SEM,FEI-XL40 [Philips©,France]): surface core, lateral orifice, ureteral loop, and black marking surface. Each experiment was repeated with three different samples from three different stents. STENTS analysis included multiple imperfection searches, defined as irregularities>10µm. RESULTS: All STENTS presented imperfections with no discernible differences. Imperfections were mainly located on the stent loop and on the lateral orifice. For STENTS without side orifice (J-Fil, Urosoft) imperfections were also reported, on the beveled cut as well as the distal loop orifice. Marking surfaces examinations found defects in the Urosoft and imperfections in the ImaJin and Stenostent. The Triasoft presented a better smoothness on marking surfaces compared to other STENTS. Additional matter was reported on the loop distal orifice for J-Fil and ImaJin but all STENTS presented irregular cross-sectional aeras. CONCLUSION: All ureteral stents are not perfectly smooth even before utilization. Imperfections were noticed regardless to stent composition or shape, and could play a role in the incrustation phenomenon, is association with inner irregularities, infection, and urine composition. Both manufacturing and material could have an impact on the stent external surface's smoothness.


Assuntos
Microscopia Eletrônica de Varredura , Stents , Ureter , Técnicas In Vitro , Teste de Materiais , Poliuretanos/química , Desenho de Prótese , Stents/efeitos adversos , Propriedades de Superfície , Ureter/cirurgia
15.
J Clin Med ; 12(8)2023 Apr 11.
Artigo em Inglês | MEDLINE | ID: mdl-37109152

RESUMO

OBJECTIVE: The aim of this review is to summarize the existing suction systems in flexible ureteroscopy (fURS) and to evaluate their effectiveness and safety. METHODS: A narrative review was performed using the Pubmed and Web of Science Core Collection (WoSCC) databases. Additionally, we conducted a search on the Twitter platform. Studies including suctions systems in fURS were included. Editorials, letters and studies reporting intervention with semirigid ureteroscopy, PCNL and mPCNL were excluded. RESULTS: A total of 12 studies were included in this review. These studies comprised one in vitro study, one ex vivo study, one experimental study and eight cohort studies. The Pubmed and WoSCC searches identified three suction techniques (Irrigation/Suctioning system with control of pressure, suction ureteral access sheath (sUAS) and direct in scope suction (DISS)), and the Twitter search identified four of them. The overall results showed that suction is an effective and safe technique that improves stone-free rates, reduces operative time and limits complication rates after fURS. CONCLUSIONS: The use of suctioning during common endourological procedures has been shown to improve safety and efficacy in several indications. However, randomized controlled trials are needed to confirm this.

16.
J Clin Med ; 12(15)2023 Jul 26.
Artigo em Inglês | MEDLINE | ID: mdl-37568309

RESUMO

INTRODUCTION: Thulium lasers (TLs), namely the Thulium fiber laser (TFL) and the Thulium:YAG (Tm:YAG), are being increasingly adopted for the conservative treatment of upper urinary tract urothelial carcinoma (UTUC). However, to date, the real clinical impact of TLs on UTUC management remains not well-characterized. We performed a review of the literature to summarize the current evidence on TLs for UTUC treatment. MATERIALS AND METHODS: We performed a systematic review in January 2023 using the Embase and Medline online databases, according to the PRISMA recommendations and using the PICO criteria. Outcomes of interest were: (i) to assess the safety and feasibility of TLs in the treatment of UTUC, and (ii) to evaluate the oncological outcomes in terms of tumor recurrence and conservative treatment failure. Moreover, we described TL characteristics and its interaction with soft tissue. RESULTS: a total of 458 articles were screened, and six full texts including 273 patients were identified. All the included studies were retrospective series. Mean patient age ranged from 66 to 73 years. The indication of a conservative treatment was elective and imperative in 21.7-85% and 15-76% of cases, respectively. Laser power settings varied from 5 to 50 W. No intraoperative complications were reported, and all the procedures were successfully performed. The tumor recurrence rate was 17.7-44%, and the indication to radical nephroureterectomy was 3.7-44% during a follow-up of 6-50 months. Most of the postoperative complications were mild and transient, and ureteral strictures were reported in two studies. Major limitations were the retrospective nature of the studies, the small sample sizes, and the short follow-up. CONCLUSIONS: TL is an effective and safe technology for endoscopic UTUC treatment. However, current available literature lacks prospective and multicentric studies with large population sizes and long-term follow-up.

17.
Artigo em Inglês | MEDLINE | ID: mdl-37906131

RESUMO

BACKGROUND: The aim of this study was to evaluate thulium fiber laser (TFL) safety and efficacy compared to high-power (HP) Holmium:YAG laser in pediatric patients who have undergone retrograde intrarenal surgery (RIRS) for kidney stones. METHODS: We retrospectively reviewed data from pediatric patients who underwent RIRS for kidney stones between 2018 and 2020. Complications were assessed 4-6 weeks postoperatively. Stone-free (SF) was defined as the absence of visible fragments or as the presence of a single residual fragment ≤2 mm at 3 months postoperative imaging. Student's t-test for continuous variables, and χ2 and Fisher's Exact Test for categorical variables were used to compare outcomes between patients treated with HP Holmium:YAG (group 1) and TFL (group 2). Univariate (UVA) and multivariate (MVA) logistic regression analyses were performed to predict SF-associated factors. RESULTS: Data from 126 pediatric patients were analyzed, 97 in group 1 and 29 in group 2. Preoperative characteristics were similar between cohorts. No major complication occurred in both groups. Group 2 had a shorter operative time (mean time 49.5 vs. 64.3 min, P=0.024). SF rate was 81.4% and 89.7% (P=0.45) and reintervention rate was 14.4% and 6.89% (P=0.046) in group 1 and 2, respectively. At UVA and MVA, the type of laser did not influence SF rate. However, prestenting and single stones were positively associated with SR rate. CONCLUSIONS: Both laser technologies are safe and effective and showed similar SF rates. TFL showed less operative time and lower re-intervention rate compared to HP Holmium:YAG. Further prospective studies are needed to corroborate our findings.

18.
urol. colomb. (Bogotá. En línea) ; 31(1): 12-13, 15/03/2022. graf, mapas
Artigo em Espanhol | LILACS, COLNAL | ID: biblio-1368866

RESUMO

Objetivos La cantidad de mujeres en especialidades médico-quirúrgicas ha aumentado. Para nuestro conocimiento, no existen políticas que reglamenten las licencias parentales en nuestro país, que permitan a lasmujeres que se desempeñan en esas especialidades vivir dicho periodo digna y equiparablemente con quienes han elegido otras carreras. Nuestro objetivo, es evaluar las publicaciones con respecto a la regulación y al apoyo a los procesos de maternidad y lactancia de los médicos. Metodos Se realizó una revisión de la literatura, de los últimos 35 años en Medline a través de Fabumed, PubReminer y Scopus, utilizando los términos Mesh: "parental leave" y "physicians". Se incluyeron todas las publicaciones sobre licencia de maternidad en médicos, de 1984 a 2019. Se hizo un análisis bibliométrico descriptivo retrospectivo de dichos artículos y un análisis de mapeo bibliométrico utilizando el programa de software: VOSviewer. Se realizó un análisis estadístico descriptivo de los datos obtenidos. Resultados Encontramos 182 publicaciones desde 1984 hasta 2019. Detectamos dos picos de publicación, en los años 1992 y 2018. El 39,6% de las publicaciones está concentrado en 20 revistas, nueve con factor de impacto mayor a 3. La mayoría de las publicaciones (85%) se encontraron en inglés y se originaron en 12 países. Conclusiones Aún no hay suficientes publicaciones para generar consenso en cuanto a aspectos relacionados con la reglamentación de la licencia de maternidad y lactancia en cirujanas. La estandarización de políticas, optimiza el ejercicio de la especialidad al mejorar el grado de satisfacción de los involucrados.


Objectives the number of women in a surgical medical specialty has increased over time. To our knowledge, there are no politics that rule parental leave in our country, with the goal of allowing women who work in these specialties to live through this period in a dignifying and comparable way as their equals who have made other career choices. The aim of this study is to assess the publications about regulation and support of maternity and breastfeeding for female doctors during their training and professional lives. Methods A literature search using Mesh terms "parental leave" and "physicians", including articles published in the last 35 years, was performed through Medline, Fabumed, PubReminer and Scopus. Every publication regarding parental leave in medical doctors from 1984 to 2019 was included. Descriptive retrospective bibliometric analysis and bibliometric mapping analysis were performed of the above-mentioned articles using VOSviewer software. Finally, a statistical descriptive analysis was performed with the obtained data. Results 184 publications from 1984 to 2019 were found. 2 Publication peaks were identified, in 1992 and 2018. 39.6% of publications are concentrated in 20 journals, 9 of which have an Impact Factor greater than 3. Most of the publications (85%) were found in English language and originated in 12 countries. Conclusions There are not enough publications to generate consensus related to the ruling of parental leave and breastfeeding in female surgeons. The standardization of politics for a specialty, optimizes its performance, as it improves the satisfaction degree of those involved.


Assuntos
Humanos , Controle Social Formal , Bibliometria , Licença Parental , Publicações Periódicas como Assunto , Escolha da Profissão , Poder Familiar , Licenciamento
19.
urol. colomb. (Bogotá. En línea) ; 29(4): 180-181, 2020.
Artigo em Inglês | LILACS, COLNAL | ID: biblio-1410616

RESUMO

"Destiny guides our fortunes more favorably than we could have expected" wrote Miguel de Cervantes Saavedra, author of the legendary novel Don Quixote of La Mancha. These words describe exactly what has happened to us over the past year. We met by chance at a urology congress last August in the City of Barranquilla. We took the opportunity to sit down unsuspectingly with coffee in hand and started talking about the big picture of urology in the world and especially in Latin America. We soon realized that despite being born in two countries as different as the United States and Colombia, we both shared similar barriers as women urologists. The truth is that despite the increase in the number of women in careers such as medicine, the growth in terms of medical and surgical specialties is still very low. According to the latest census of the American Urological Association (AUA), female urologists currently make up only 9.9% of the total membership in the US academy.[1] What is contradictory is that many studies have evaluated the change in the workforce that has been occurring in this branch of medicine for a few years, since it is assumed that by 2060 there will be a growth in the number of women of 3.7% versus 1.3% compared to men.[2] These two surprising facts forced us to think about the need to find solutions.


"El destino guía nuestra suerte más favorablemente de lo que podíamos esperar", escribió Miguel de Cervantes Saavedra, autor de la legendaria novela Don Quijote de la Mancha. Estas palabras describen exactamente lo que nos ha ocurrido en el último año. Nos conocimos por casualidad en un congreso de urología el pasado mes de agosto en la ciudad de Barranquilla. Aprovechamos la oportunidad para sentarnos desprevenidamente con un café en la mano y empezamos a hablar sobre el gran panorama de la urología en el mundo y especialmente en Latinoamérica. Pronto nos dimos cuenta que a pesar de haber nacido en dos países tan diferentes como Estados Unidos y Colombia, ambas compartíamos barreras similares como mujeres urólogas. Lo cierto es que a pesar del aumento del número de mujeres en carreras como medicina, el crecimiento en cuanto a especialidades médicas y quirúrgicas es aún muy bajo. Según el último censo de la Asociación Americana de Urología (AUA), en la actualidad las mujeres urólogas representan sólo el 9,9% del total de miembros de la academia estadounidense[1] Lo contradictorio es que muchos estudios han evaluado el cambio en la fuerza laboral que se viene dando en esta rama de la medicina desde hace algunos años, pues se presume que para el año 2060 habrá un crecimiento en el número de mujeres del 3,7% frente al 1,3% de los hombres[2] Estos dos sorprendentes datos nos obligaron a pensar en la necesidad de encontrar soluciones.


Assuntos
Humanos , Feminino , Especialidades Cirúrgicas , Mulheres , Urologistas , Trabalho , Academias e Institutos , Recursos Humanos
20.
urol. colomb. (Bogotá. En línea) ; 29(4): 245-246, 2020. ilus
Artigo em Inglês | LILACS, COLNAL | ID: biblio-1411082

RESUMO

The presence of women in medicine and urology has been increasing. However, there is a large disparity in leadership positions. In 2017, women constituted 3.3% of chairs, 4.5% of vice-chairs, and 7.9% of division directors in the United States,[1] similar positions in Colombia. It is unclear why this deep gender gap exists in urology. Multifactorial and specialty-specific factors may include lack of mentorship, sponsorship, and limited female role models in leadership positions.[2] According to the Association of Medical Colleges (AAMC), many women do not find mentors in surgical specialties. This lack of mentorship may limit women from accessing similar opportunities to their male counterparts.


La presencia de mujeres en la medicina y la urología ha ido en aumento. Sin embargo, existe una gran disparidad en los puestos de liderazgo. En 2017, las mujeres constituían el 3,3% de las cátedras, el 4,5% de las vicepresidencias y el 7,9% de los directores de división en Estados Unidos,[1] cargos similares en Colombia. No está claro por qué existe esta profunda brecha de género en urología. Según la Asociación de Facultades de Medicina (AAMC), muchas mujeres no encuentran mentores en las especialidades quirúrgicas. Esta falta de mentores puede limitar el acceso de las mujeres a oportunidades similares a las de sus homólogos masculinos.


Assuntos
Humanos , Feminino , Especialidades Cirúrgicas , Identidade de Gênero , Liderança , Associação , Faculdades de Medicina
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