Detalhe da pesquisa
1.
Discovery of Novel Acetylcholinesterase Inhibitors as Potential Candidates for the Treatment of Alzheimer's Disease.
Int J Mol Sci
; 20(4)2019 Feb 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-30823604
2.
Discovery of Non-Peptidic Compounds against Chagas Disease Applying Pharmacophore Guided Molecular Modelling Approaches.
Molecules
; 23(12)2018 Nov 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30469538
3.
Competitive protein tyrosine phosphatase 1B (PTP1B) inhibitors, prenylated caged xanthones from Garcinia hanburyi and their inhibitory mechanism.
Bioorg Med Chem
; 25(8): 2498-2506, 2017 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28318895
4.
MP-V1 from the Venom of Social Wasp Vespula vulgaris Is a de Novo Type of Mastoparan that Displays Superior Antimicrobial Activities.
Molecules
; 21(4): 512, 2016 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27104500
5.
Structural importance of the C-terminal region in pig aldo-keto reductase family 1 member C1 and their effects on enzymatic activity.
BMC Struct Biol
; 15: 1, 2015 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-25583233
6.
Novel chemical scaffolds of the tumor marker AKR1B10 inhibitors discovered by 3D QSAR pharmacophore modeling.
Acta Pharmacol Sin
; 36(8): 998-1012, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26051108
7.
New insights in the activation of human cholesterol esterase to design potent anti-cholesterol drugs.
Mol Divers
; 18(1): 119-31, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24173651
8.
Discovery of Lonafarnib-Like Compounds: Pharmacophore Modeling and Molecular Dynamics Studies.
ACS Omega
; 5(4): 1773-1781, 2020 Feb 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32039312
9.
A Computational Approach with Biological Evaluation: Combinatorial Treatment of Curcumin and Exemestane Synergistically Regulates DDX3 Expression in Cancer Cell Lines.
Biomolecules
; 10(6)2020 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32512851
10.
Structure-Based Drug Designing Recommends HDAC6 Inhibitors To Attenuate Microtubule-Associated Tau-Pathogenesis.
ACS Chem Neurosci
; 10(3): 1326-1335, 2019 03 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30407786
11.
Computational Simulations Identified Two Candidate Inhibitors of Cdk5/p25 to Abrogate Tau-associated Neurological Disorders.
Comput Struct Biotechnol J
; 17: 579-590, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31073393
12.
Natural compounds as potential Hsp90 inhibitors for breast cancer-Pharmacophore guided molecular modelling studies.
Comput Biol Chem
; 83: 107113, 2019 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-31493740
13.
Pharmacotherapeutics and Molecular Mechanism of Phytochemicals in Alleviating Hormone-Responsive Breast Cancer.
Oxid Med Cell Longev
; 2019: 5189490, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31089409
14.
In Silico Study Probes Potential Inhibitors of Human Dihydrofolate Reductase for Cancer Therapeutics.
J Clin Med
; 8(2)2019 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30754680
15.
Identification of Novel Scaffolds with Dual Role as Antiepileptic and Anti-Breast Cancer.
IEEE/ACM Trans Comput Biol Bioinform
; 16(5): 1663-1674, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30334765
16.
Investigation of novel chemical scaffolds targeting prolyl oligopeptidase for neurological therapeutics.
J Mol Graph Model
; 88: 92-103, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30665156
17.
Computational Simulations Identify Pyrrolidine-2,3-Dione Derivatives as Novel Inhibitors of Cdk5/p25 Complex to Attenuate Alzheimer's Pathology.
J Clin Med
; 8(5)2019 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31137734
18.
Discovery of Potential Plant-Derived Peptide Deformylase (PDF) Inhibitors for Multidrug-Resistant Bacteria Using Computational Studies.
J Clin Med
; 7(12)2018 Dec 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-30563019
19.
Investigation of non-hydroxamate scaffolds against HDAC6 inhibition: A pharmacophore modeling, molecular docking, and molecular dynamics simulation approach.
J Bioinform Comput Biol
; 16(3): 1840015, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29945500
20.
Targeting natural compounds against HER2 kinase domain as potential anticancer drugs applying pharmacophore based molecular modelling approaches.
Comput Biol Chem
; 74: 327-338, 2018 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-29702367