Detalhe da pesquisa
1.
Bromodomain inhibition overcomes treatment resistance in distinct molecular subtypes of melanoma.
Proc Natl Acad Sci U S A
; 119(34): e2206824119, 2022 08 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35969744
2.
PHIP drives glioblastoma motility and invasion by regulating the focal adhesion complex.
Proc Natl Acad Sci U S A
; 117(16): 9064-9073, 2020 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32273388
3.
PHIP as a therapeutic target for driver-negative subtypes of melanoma, breast, and lung cancer.
Proc Natl Acad Sci U S A
; 115(25): E5766-E5775, 2018 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29866840
4.
Drug responses are conserved across patient-derived xenograft models of melanoma leading to identification of novel drug combination therapies.
Br J Cancer
; 122(5): 648-657, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31857724
5.
Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis.
Cancer Cell
; 9(3): 157-73, 2006 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-16530701
6.
Platelet-derived growth factor-alpha receptor activation is required for human cytomegalovirus infection.
Nature
; 455(7211): 391-5, 2008 Sep 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-18701889
7.
The Irreversible FGFR Inhibitor KIN-3248 Overcomes FGFR2 Kinase Domain Mutations.
Clin Cancer Res
; 30(10): 2181-2192, 2024 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38437671
8.
Discovery of KIN-3248, An Irreversible, Next Generation FGFR Inhibitor for the Treatment of Advanced Tumors Harboring FGFR2 and/or FGFR3 Gene Alterations.
J Med Chem
; 67(3): 1734-1746, 2024 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38267212
9.
Dual Targeting of EGFR and MTOR Pathways Inhibits Glioblastoma Growth by Modulating the Tumor Microenvironment.
Cells
; 12(4)2023 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36831214
10.
Functional genomic analysis of adult and pediatric brain tumor isolates.
bioRxiv
; 2023 Jan 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36711964
11.
Pan-Cancer Pharmacogenomic Analysis of Patient-Derived Tumor Cells Using Clinically Relevant Drug Exposures.
Mol Cancer Ther
; 22(9): 1100-1111, 2023 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37440705
12.
Cannabidiol inhibits RAD51 and sensitizes glioblastoma to temozolomide in multiple orthotopic tumor models.
Neurooncol Adv
; 4(1): vdac019, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35356807
13.
Pitfalls and Rewards of Setting Up a Liquid Biopsy Approach for the Detection of Driver Mutations in Circulating Tumor DNAs: Our Institutional Experience.
J Pers Med
; 12(11)2022 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36579573
14.
Cannabidiol Treatment Results in a Common Gene Expression Response Across Aggressive Cancer Cells from Various Origins.
Cannabis Cannabinoid Res
; 6(2): 148-155, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33912679
15.
Niraparib Suppresses Cholangiocarcinoma Tumor Growth by Inducing Oxidative and Replication Stress.
Cancers (Basel)
; 13(17)2021 Aug 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-34503215
16.
Nuclear Receptor Coactivator NCOA3 Regulates UV Radiation-Induced DNA Damage and Melanoma Susceptibility.
Cancer Res
; 81(11): 2956-2969, 2021 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33766890
17.
Prevalence of Homologous Recombination Pathway Gene Mutations in Melanoma: Rationale for a New Targeted Therapeutic Approach.
J Invest Dermatol
; 141(8): 2028-2036.e2, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33610559
18.
Dinaciclib, a cyclin-dependent kinase inhibitor, suppresses cholangiocarcinoma growth by targeting CDK2/5/9.
Sci Rep
; 10(1): 18489, 2020 10 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33116269
19.
Tissues Harvested Using an Automated Surgical Approach Confirm Molecular Heterogeneity of Glioblastoma and Enhance Specimen's Translational Research Value.
Front Oncol
; 9: 1119, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31750239
20.
Novel tumor suppressor role of miRNA-876 in cholangiocarcinoma.
Oncogenesis
; 8(8): 42, 2019 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31409772